Results 91 to 100 of about 936,897 (362)

Postoperative and Postpartum Onset of Chronic Parkinsonism: Four Case Reports

International Journal of Medical Students, 2014
Background: Certain environmental exposures have been linked to the development of parkinsonism. We report four cases in which the onset of chronic parkinsonism occurred immediately or soon after surgery or childbirth.
Manish Ramani B., Marcie Rabin L., Roger Kurlan   +2 more
doaj   +3 more sources

Adaptive Brain Stimulation for Movement Disorders [PDF]

, 2018
Deep brain stimulation (DBS) has markedly changed how we treat movement disorders including Parkinson's disease (PD), dystonia, and essential tremor (ET).
Beudel, M, Cagnan, H, Little, S
core   +3 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Automatic Posture and Movement Tracking of Infants with Wearable Movement Sensors [PDF]

arXiv, 2019
Infants' spontaneous and voluntary movements mirror developmental integrity of brain networks since they require coordinated activation of multiple sites in the central nervous system. Accordingly, early detection of infants with atypical motor development holds promise for recognizing those infants who are at risk for a wide range of ...
arxiv  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Disorders of the Oral Cavity in Parkinson’s Disease and Parkinsonian Syndromes

Parkinson's Disease, 2015
Awareness of nonmotor symptoms of Parkinson’s disease is growing during the last decade. Among these, oral cavity disorders are, although prevalent, often neglected by the patients, their caregivers, and physicians.
Yair Zlotnik, Yacov Balash, Amos D. Korczyn, Nir Giladi, Tanya Gurevich   +4 more
doaj   +1 more source

Takayasu's Arteritis in a Patient with Sydenham's Chorea: Is There an Association?

Tremor and Other Hyperkinetic Movements, 2012
Background: Takayasu's arteritis (TA) has been associated with many conditions. Herein described is a case of TA in a patient with rheumatic fever complicated with Sydenham's chorea.Case Report: A 17-year-old female presented at age 6 with ...
Thiago C. Vale, Ricardo O. Maciel, Débora P. Maia, Rogério Beato, Francisco Cardoso   +4 more
doaj   +1 more source

Antipsychotic-Induced Movement Disorders in Long-Stay Psychiatric Patients and 45 Tag SNPs in 7 Candidate Genes: A Prospective Study [PDF]

, 2012
Objective: Four types of antipsychotic-induced movement disorders: tardive dyskinesia (TD), parkinsonism, akathisia and tardive dystonia, subtypes of TD (orofacial and limb truncal dyskinesia), subtypes of parkinsonism (rest tremor, rigidity, and ...
Al Hadithy, A.F.Y. (Asmar), Amin, N. (Najaf), Bakker, P.R. (Roberto), Duijn, C.M. (Cornelia) van, Harten, P.N. (Peter) van, Os, J. (Jim) van   +5 more
core   +2 more sources

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

How do eyes and brain search a randomly structured uninformative scene? Exploiting a basic interplay of attention and memory [PDF]

Eye Movement: Developmental Perspectives, Dysfunctions and Disorders in Humans, Ed. L. C. Stewart, Chapter 1, pp. 1-48, 2013. NOVA Science Publisher, Inc., ISBN: 978-1-62808-601-0, 2020
We tracked the eye movements of seven young and seven older adults performing a conjunctive visual search task similar to that performed by two highly trained monkeys in an original influential study of Motter and Belky (1998a, 1998b). We obtained results consistent with theirs regarding elements of perception, selection, attention and object ...
arxiv