Results 111 to 120 of about 936,897 (362)

Exercise enhances motor skill learning by neurotransmitter switching in the adult midbrain. [PDF]

, 2020
Physical exercise promotes motor skill learning in normal individuals and those with neurological disorders but its mechanism of action is unclear. We find that one week of voluntary wheel running enhances the acquisition of motor skills in normal adult ...
Li, Hui-Quan, Spitzer, Nicholas C
core  

Emergencies in movement disorders [PDF]

, 2021
Movement disorders constitute a large group of diseases that affect the control of voluntary motor activity without a direct impact on sensation and strength. Usual clinical course is slow, progressive and can be treated in an outpatient clinic. However,
Hero, Mario, Rački, Valentino, Vuletić, Vladimira   +2 more
core   +1 more source

From 2D to 3D gamma passing rate tolerance and action limits for patient‐specific quality assurance in volumetric‐modulated arc therapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Volumetric modulated arc therapy (VMAT) requires an accurate patient‐specific quality assurance (PSQA) program. In clinical practice, this is usually performed using the γ‐index and the two‐dimensional gamma passing rate (2D %GP). A three‐dimensional (3D) index incorporating the patient anatomy could be more useful for the 3D dose ...
Christos Zarros, George Patatoukas, Nikos Kollaros, Marina Chalkia, Andromachi Kougioumtzopoulou, Vasilios Kouloulias, Kalliopi Platoni   +6 more
wiley   +1 more source

A translational approach to capture gait signatures of neurological disorders in mice and humans

Scientific Reports, 2017
A method for capturing gait signatures in neurological conditions that allows comparison of human gait with animal models would be of great value in translational research.
Lauren Broom, Brian A. Ellison, Audrey Worley, Lara Wagenaar, Elina Sörberg, Christine Ashton, David A. Bennett, Aron S. Buchman, Clifford B. Saper, Ludy C. Shih, Jeffrey M. Hausdorff, Veronique G. VanderHorst   +11 more
doaj   +1 more source

The burden of burnout: Understanding its prevalence and organizational drivers in medical physics

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Burnout is a work‐related syndrome characterized by increased levels of emotional exhaustion (EE) and depersonalization (DP) along with decreased levels of personal achievement. In the healthcare setting, higher burnout levels have been associated with negative impacts on personnel, an increased risk of errors, and a decrease in the
Deborah Schofield, C. Lynn Chevalier, Laurence Court, William Harmsen, Akiva Turner   +4 more
wiley   +1 more source

Stiff person syndrome and other immune-mediated movement disorders - new insights [PDF]

, 2016
PURPOSE OF REVIEW: This review highlights the recent developments in immune-mediated movement disorders and how they reflect on clinical practice and our understanding of the underlying pathophysiological mechanisms.
Balint, B, Bhatia, KP
core   +1 more source

Dosimetric evaluation and clinical application of collimated apertures with proton beam line scanning in stereotactic radiotherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Stereotactic radiotherapy (SRT) is a highly effective treatment with precision for small, localized lesions. Proton therapy, characterized by the Bragg peak, offers superior dose conformity compared to photon‐based approaches. However, challenges remain in minimizing lateral penumbra and optimizing dose delivery, particularly for small
Chen‐Yu Chou, Hsiao‐Chieh Huang, Shen‐Hao Lee, Shih‐Ming Hsu   +3 more
wiley   +1 more source

Long-Term Real-World Experience with Safinamide in Patients with Parkinson’s Disease

Brain Sciences
Introduction: Randomized clinical trials should be complemented with data from real-world studies. We report our long-term experience with safinamide in a movement disorders unit.
Anna Planas-Ballvé, Núria Caballol Pons, Alejandro Peral Quirós, Isabel Gómez Ruiz, Marta Balagué Marmaña, Alexander J. Velázquez Ballester, Dolors Lozano Moreno, Asunción Ávila Rivera   +7 more
doaj   +1 more source

Functional movement disorders: Five new things. [PDF]

, 2017
Purpose of review: Functional movement disorders (FMD) are commonly seen in neurologic practice, but are associated with poor outcomes. Recent years have seen a resurgence of interest in this area, with new developments in pathophysiologic understanding ...
Edwards, M, Pringsheim, T
core   +1 more source

Mitochondrial DNA disorders in neuromuscular diseases in diverse populations

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao, Katherine R Schon, Jana Vandrovcova, Özlem Yayıcı Köken, Sharika Raga, Kireshnee Naidu, Maryke Schoonen, Nimita Rani, Pedro Tomaselli, Dipti Baskar, Musambo Kapapa, Ipek Polat, Lindsay A Wilson, Kumarasamy Thangaraj, Uluç Yiş, Bevinahalli N Nandeesh, David Bearden, Michelle Kvalsund, Franclo Henning, Seena Vengalil, Atchayaram Nalini, Claudia F. R. Sobreira, Wilson Marques, Haluk Topoloğlu, Michael G Hanna, Sireesha Yareeda, Venugopalan Y Vishnu, Francois H van der Westhuizen, Izelle Smuts, Surita Meldau, Jo Wilmshurst, Büşranur Çavdarlı, Jeannine Heckmann, Patrick F Chinnery, Rita Horvath   +34 more
wiley   +1 more source