Results 51 to 60 of about 974,805 (252)

Association of Cumulative Lead Exposure with Parkinson's Disease [PDF]

, 2010
BACKGROUND. Research using reconstructed exposure histories has suggested an association between heavy metal exposures, including lead, and Parkinson's disease (PD), but the only study that used bone lead, a biomarker of cumulative lead exposure, found a
Hersh, Bonnie, Hu, Howard, Nie, Huiling, Saint-Hilaire, Marie-Helene, Schwartz, Joel, Simon, David K., Sudarsky, Lewis, Weisskopf, Marc G., Weuve, Jennifer, Wright, Robert O.   +9 more
core   +3 more sources

Functional movement disorders [PDF]

Current Opinion in Neurology, 2017
Purpose of review The review highlights the clinical presentation of functional movement disorders (FMDs) and presents current evidence on bedside signs and paraclinical tests to differentiate them from other neurological disorders. Recent findings FMDs are diagnosed by the presence
Barbey, Anita, Aybek, Selma
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Neurovisceral phenotypes in the expression of psychiatric symptoms [PDF]

, 2015
This review explores the proposal that vulnerability to psychological symptoms, particularly anxiety, originates in constitutional differences in the control of bodily state, exemplified by a set of conditions that include Joint Hypermobility, Postural ...
Aktas, Al-Rawi, Anderson, Andrew P. Owens, Arunkalaivanan, Baeza-Velasco, Bagai, Bayles, Beacher, Benarroch, Bendik, Benrud-Larson, Birner, Boddaert, Bohora, Bovell, Bulbena, Bulbena, Bulbena, Bulbena, Bulbena, Bulbena, Buodo, Castori, Child, Christopher J. Mathias, Cohen, Critchley, Critchley, Critchley, De Kort, De Wandele, Eccles, Eccles, Eccles, Ekman, Engel, Esler, Esler, Fenton, Friedman, Fu, Ganzeboom, Garcia Campayo, Gazit, Giada, Gracie, Grahame, Grahame, Grubb, Hakim, Hakim, Hugo D. Critchley, Hunt, Jessica A. Eccles, Joyner, Kanjwal, Kapoor, Karaca, Karan, Kaya, Kelly, Khurana, Khurana, Kirby, Koldas Dogan, Kouakam, Lader, Lambert, Lammers, Lee, Leftheriotis, Lemche, Lemche, Lewis, Lewis, Linzer, Lonsdale-Eccles, Low, Luborsky, Mallorqui-Bague, Martin-Santos, Masuki, Mathias, Mathias, Mayer-Gross, McGrady, Milhorat, Mohammed, Morgan, Mulvey, Nicotra, Nijs, Noppen, Ocon, Ocon, Ofluoglu, Ojha, Parsaik, Paulus, Peggs, Phillips, Porges, Pritchard, Raj, Raj, Ramos, Ross, Rozen, Sanches, Satoshi Umeda, Savage, Schievink, Schondorf, Seth, Sierra, Sierra, Sierra, Simeon, Sledge, Smith, Stachenfeld, Stewart, Stoler, Tinkle, Tracey, Umeda, Ventura, Vounotrypidis, Wooley, Yazici, Zarate, Zysko   +132 more
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Chronic adaptive deep brain stimulation for Parkinson’s disease: clinical outcomes and programming strategies

npj Parkinson's Disease
Adaptive deep brain stimulation (DBS) dynamically adjusts stimulation amplitude based on neurophysiological feedback and may alleviate residual motor fluctuations in patients with Parkinson’s disease.
Johannes L. Busch, Jonathan Kaplan, Jennifer K. Behnke, Victoria S. Witzig, Luisa Drescher, Jeroen G. V. Habets, Andrea A. Kühn   +6 more
doaj   +1 more source

Comparable Botulinum Toxin Outcomes between Primary and Secondary Blepharospasm: A Retrospective Analysis

Tremor and Other Hyperkinetic Movements, 2014
Background: Blepharospasm is a focal cranial dystonia, which could be idiopathic in origin or secondary to an underlying disorder that commonly impairs quality of life.
Daniel Martinez-Ramirez, Juan C. Giugni, Erin Hastings, Aparna W. Shukla, Irene A. Malaty, Michael S. Okun, Ramon L. Rodriguez   +6 more
doaj   +1 more source

Treatment of Acute Neuroleptic‐Induced Movement Disorders [PDF]

, 1994
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90365/1/j.1875-9114.1994.tb02851.x ...
Guthrie, Sally K., Tonda, Margaret E.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Takayasu's Arteritis in a Patient with Sydenham's Chorea: Is There an Association?

Tremor and Other Hyperkinetic Movements, 2012
Background: Takayasu's arteritis (TA) has been associated with many conditions. Herein described is a case of TA in a patient with rheumatic fever complicated with Sydenham's chorea.Case Report: A 17-year-old female presented at age 6 with ...
Thiago C. Vale, Ricardo O. Maciel, Débora P. Maia, Rogério Beato, Francisco Cardoso   +4 more
doaj   +1 more source