Results 51 to 60 of about 936,897 (362)

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Movement Disorders and Neurometabolic Diseases [PDF]

, 2018
Many inherited metabolic disorders cause movement disorders in children. This review focuses on chorea, dystonia, myoclonus, tremor, and parkinsonism. Broad categories commonly responsible for pediatric movement disorders include mitochondrial disorders,
Christensen, Celanie K., Walsh, Laurence
core   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Brittle Dyskinesia Following STN but not GPi Deep Brain Stimulation

Tremor and Other Hyperkinetic Movements, 2014
Background: The aim was to describe the prevalence and characteristics of difficult to manage dyskinesia associated with subthalamic nucleus (STN) deep brain stimulation (DBS).
Ashok Sriram, Kelly D. Foote, Genko Oyama, Joshua Kwak, Pamela R. Zeilman, Michael S. Okun   +5 more
doaj   +1 more source

Towards Blockchain-based Remote Management Systems for Patients with Movement Disorders [PDF]

arXiv, 2023
Secure storage and sharing of patients' medical data over the Internet are part of the challenges for emerging healthcare systems. The use of blockchain technology in medical Internet of things systems can be considered a safe and novel solution to overcome such challenges. Patients with movement disorders require multi-disciplinary management and must
arxiv  

Flunarizine and cinnarizine-induced parkinsonism: 25 years of de Melo-Souza's syndrome [PDF]

, 2009
Universidade Federal do Paraná Hospital de Clínicas Internal Medicine DepartmentUniversidade Federal de São Paulo (UNIFESP) Neurology and Neurosurgery Department Movement Disorders UnitUNIFESP, Neurology and Neurosurgery Department Movement Disorders ...
Ferraz, Henrique B., Munhoz, Renato Puppi, Teive, Hélio A. G.   +2 more
core   +2 more sources

Movement Disorders and Neuromodulation [PDF]

Neurology Research International, 2012
Movement disorders are neurological conditions affecting speed, fluency, quality, and ease of movement. Deep brain stimulation (DBS) is used to treat advanced Parkinson’s disease, essential tremor, and dystonia. Possible target sites for DBS include the ventral intermediate nucleus of the thalamus, the globus pallidus internus, and the subthalamic ...
openaire   +3 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Method of Tremor Levodopa Responsiveness Assessment and Its Correlation With Clinical Factors in Parkinson’s Disease: Outcomes of the Acute Levodopa Challenge Test

Parkinson's Disease
Conclusions: The aLR, rather than the %LR, is a more effective assessment method for evaluating the efficacy of levodopa for treating tremors in PD.
Fangfei Li, Shaosong Xing, Yusha Cui, Lingyan Ma, Rui Yan, Genliang Liu, Tao Feng   +6 more
doaj   +1 more source

Generalized Dystonia and Paroxysmal Dystonic Attacks due to a Novel ATP1A3 Variant

Tremor and Other Hyperkinetic Movements, 2019
Background: Paroxysmal movement disorders are a heterogeneous group of neurological diseases, better understood in recent years thanks to widely available genetic testing.
Carlos Zúñiga-Ramírez, Mirelle Kramis-Hollands, Rodrigo Mercado-Pimentel, Héctor Alberto González-Usigli, Michel Sáenz-Farret, Alberto Soto-Escageda, Alfonso Fasano   +6 more
doaj   +1 more source