Results 41 to 50 of about 459,876 (311)

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

Heterogeneous Patterns of Striatal Dopamine Loss in Patients with Young- versus Old-Onset Parkinson's Disease: Impact on Clinical Features [PDF]

open access: yes, 2019
OBJECTIVE: Ample evidence has suggested that age at onset of Parkinson's disease (PD) is associated with heterogeneous clinical features in individuals.
이양현   +4 more
core   +1 more source

Emerging Concepts of Motor Reserve in Parkinson's Disease [PDF]

open access: yes, 2020
The concept of cognitive reserve (CR) in Alzheimer's disease (AD) explains the differences between individuals in their susceptibility to AD-related pathologies.
이필휴, 손영호, 정석종
core   +1 more source

The severity progression of non-motor symptoms in Parkinson’s disease: a 6-year longitudinal study in Taiwanese patients

open access: yesScientific Reports, 2021
Nonmotor symptoms (NMSs) cause major burden in patients with Parkinson’s disease (PD). Previous NMSs progression studies mostly focused on the prevalence. We conducted a longitudinal study to identify the progression pattern by the severity.
Yi-Chieh Chen   +6 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Clinical Characteristics of 49 Patients with Psychogenic Movement Disorders in a Tertiary Clinic in Turkey

open access: yes, 2009
Patients admitted to movement disorders outpatient unit at a university hospital between January 2002 and June 2007 were screened for psychogenic movement disorders (PMDs).
Uluduz, Derya   +6 more
core   +1 more source

Association between Olfactory Deficit and Motor and Cognitive Function in Parkinson's Disease [PDF]

open access: yes, 2020
Objective: To investigate whether baseline olfactory dysfunction in Parkinson's disease (PD) patients is associated with baseline and longitudinal motor and cognitive function.
이양현   +5 more
core   +1 more source

Sleep disturbance in movement disorders – insights, treatments and challenges [PDF]

open access: yes, 2021
Sleep and circadian rhythm disturbances are central features of many movement disorders, exacerbating motor and non-motor symptoms and impairing quality of life.
Tijssen, Marina A. J.   +8 more
core   +1 more source

Method of Tremor Levodopa Responsiveness Assessment and Its Correlation With Clinical Factors in Parkinson’s Disease: Outcomes of the Acute Levodopa Challenge Test

open access: yesParkinson's Disease
Conclusions: The aLR, rather than the %LR, is a more effective assessment method for evaluating the efficacy of levodopa for treating tremors in PD.
Fangfei Li   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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