Results 61 to 70 of about 2,227,949 (244)

Dynamic Response Analysis of Rutting Resistance Performance of High Modulus Asphalt Concrete Pavement

open access: yesApplied Sciences, 2018
In order to systematically study the rutting resistance performance of High-Modulus Asphalt Concrete (HMAC) pavements, a finite element method model of HMAC pavement was established using ABAQUS software.
Chundi Si   +6 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Forced vibration of delaminated Timoshenko beams subjected to a moving load

open access: yesScience and Engineering of Composite Materials, 2012
A composite beam with single delamination under the action of moving load has been modeled accounting for the Poisson’s effect, shear deformation, and rotary inertia.
Kargarnovin Mohammad H.   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluation and Comparison of a Large Machine Tool Structure with ISO Standard Alignment Tests [PDF]

open access: yes, 2009
In order to satisfactorily machine precision components it is necessary for machine tools to be able to achieve extremely high levels of geometric accuracy.
Longstaff, Andrew P.   +4 more
core   +5 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Out-of-plane vibrations of curved nonprismatic beam under a moving load

open access: yesJournal of Civil Engineering and Management, 2012
The forced vibrations of a curved-in-plane nonprismatic beam with a variable cross section and any curvature, generated by a load moving at a variable velocity are analyzed.
Małgorzata Meissner, Piotr Ruta
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Mathematical models for optimal shakedown trusses design problems in case of moving load

open access: yesTechnological and Economic Development of Economy, 2007
Prisitaikomumo teorija, nagrinejanti tampriai plastiškas konstrukcijas, veikiama kintamosios kartotines apkrovos, leidžia judamaja apkrova traktuoti kaip atskira kartotinai kintančiu jegu atveji. Apkrovai leidžiama “judeti” bet kuria konstrukcijos dalimi:
Juozas Atkočiūnas   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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