Results 251 to 260 of about 9,249 (288)

Loperamide‐induced enhancement of moxidectin availability in cattle

Journal of Veterinary Pharmacology and Therapeutics, 2002
Moxidectin (MXD) is a milbemycin endectocide compound active at extremely low dosages against a wide variety of nematode and arthropod parasites. Different pharmacological approaches are currently being tested to delay the bile‐faecal elimination and to obtain increased systemic availability for endectocide molecules in ruminants.
A, Lifschitz, G, Virkel, J, Sallovitz, F, Imperiale, A, Pis, C, Lanusse   +5 more
openaire   +2 more sources

Clinical trial of moxidectin oral gel in horses

Veterinary Parasitology, 1997
A clinical trial carried out over 98 days was done to evaluate treatment of horses with moxidectin gel for efficacy as measured by (1) reduction in the production of parasite ova post treatment, (2) a comparison of the posttreatment parasite egg count suppression of moxidectin to ivermectin, and (3) assessment of the field safety, animal acceptance of ...
J A, DiPietro, D E, Hutchens, T F, Lock, K, Walker, A J, Paul, C, Shipley, D, Rulli   +6 more
openaire   +2 more sources

Efficacy of moxidectin against gastrointestinal nematodes of cattle

Veterinary Record, 1992
Three groups of 11 naturally infected crossbred beef calves were injected subcutaneously with moxidectin 1 per cent injectable at 0.2 or 0.3 mg moxidectin/kg bodyweight or with the unmedicated vehicle. Nematode infections had been acquired during grazing from December to April.
J C, Williams, S A, Barras, G T, Wang
openaire   +2 more sources

Pharmacokinetics assessment of moxidectin long-acting formulation in cattle

Veterinary Parasitology, 2007
The plasma kinetics disposition of moxidectin following a subcutaneous administration with a long-acting formulation (Cydectin) 10%, Fort Dodge Animal Health, France) at the recommended dose of 1 mg kg(-1) body weight was evaluated in Charolais cattle breed (five females weighing 425-450 kg) for 120 days.
Dupuy, Jacques, Sutra, Jf, Alvinerie, A
openaire   +3 more sources

[Moxidectin poisoning in a foal?].

Tijdschrift voor diergeneeskunde, 1999
A 2 day old foal was presented with central nervous depression (coma) after moxidectin overdose. Moxidectin belongs to the milbemycin anthelmintics which elicit their working mechanism through a GABA (gamma-aminobutyric acid)-stimulatory mode of action. The foal developed profound hypothermia, bradycardia and hypoventilation.
L S, Goehring, M M, Sloet van Oldruitenborgh-Oosterbaan   +1 more
openaire   +1 more source

Respiratory failure attributable to moxidectin intoxication in a dog

Journal of the American Veterinary Medical Association, 1999
A 5-month-old 22-kg (48.4-lb) sexually intact male Collie was examined after ingesting a moxidectin-containing deworming medication. The dog was comatose and had respiratory arrest after progressively worsening lethargy, ataxia, and seizures. Exposure was confirmed by isolation of moxidectin from a biopsy specimen of adipose tissue, using liquid ...
M W, Beal, R H, Poppenga, W J, Birdsall, D, Hughes   +3 more
openaire   +2 more sources

Efficacy of Moxidectin Oral Gel against Onchocerca cervicalis Microfilariae

The Journal of Parasitology, 1995
During a series of dose-titration experiments designed to evaluate the efficacy of moxidectin oral gel against equine gastrointestinal parasites, infection with Onchocerca cervicalis was diagnosed in 25 of 82 ponies prior to treatment. Microfilariae were identified in full-thickness skin biopsies taken from the ventral midline.
C M, Monahan, M R, Chapman, D D, French, T R, Klei   +3 more
openaire   +2 more sources

Efficacy of moxidectin against nematodes in naturally infected sheep

Veterinary Record, 1994
The activity of an oral drench of moxidectin against nematodes in naturally infected sheep known to harbour Nematodirus species was evaluated at doses of 0.2 and 0.4 mg/kg bodyweight. Moxidectin was 100 per cent effective against nematodes in the abomasum and 100 per cent effective against nematodes in the small intestine except for adult ...
G C, Coles, D J, Giordano-Fenton, J P, Tritschler   +2 more
openaire   +2 more sources

Efficacy and safety of moxidectin compared with ivermectin against Strongyloides stercoralis infection in adults in Laos and Cambodia: a randomised, double-blind, non-inferiority, phase 2b/3 trial.

Lancet. Infectious Diseases (Print), 2023
Viviane P. Sprecher, D. Hofmann, Vanthanom Savathdy, Phengsavanh Xayavong, Chomseng Norkhankhame, R. Huy, Virak Khieu, S. Sayasone, J. Hattendorf, Jennifer Keiser   +9 more
semanticscholar   +1 more source

Sheep scab mites show resistance to moxidectin

Veterinary Record, 2018
It's been almost three years since over 200,000 saiga antelopes died in central Kazakhstan, in a mass mortality event that shocked researchers and wildlife experts alike. But now, as Georgina Mills explains, research has revealed that there was more to the deaths than first thought.
openaire   +1 more source