Results 81 to 90 of about 6,633 (220)

Evaluation of an FDA approved library against laboratory models of human intestinal nematode infections [PDF]

, 2016
Treatment options for infections with soil-transmitted helminths (STH) - Ascaris lumbricoides, Trichuris trichiura and the two hookworm species, Ancylostoma duodenale and Necator americanus - are limited despite their considerable global health burden ...
Adelfio, Roberto, Cowan, Noemi, Keiser, Jennifer, Panic, Gordana, Scandale, Ivan, Vargas, Mireille   +5 more
core   +2 more sources

Grassland management and helminth control on cattle farms [PDF]

, 2017
Farmers manage their pastures and grazing animals primarily to ensure that swards provide adequate, quality nutrients to support animal performance, but it is also possible to provide useful levels of parasite control without compromising production.
Forbes, Andrew
core   +1 more source

Exposure of gut bacterial isolates to the anthelminthic drugs, ivermectin and moxidectin, leads to antibiotic-like phenotypes of growth inhibition and adaptation

Communications Biology
Due to their broad-spectrum activities, ivermectin and moxidectin are widely used anthelminthics in veterinary and human medicine. However, ivermectin has recently been shown to perturbate bacterial growth.
Julian Dommann, Jennifer Keiser, Julian Garneau, Alison Gandelin, Carlo Casanova, Peter M. Keller, Somphou Sayasone, Pascale Vonaesch, Pierre H. H. Schneeberger   +8 more
doaj   +1 more source

Gastrointestinal nematodes of Ovis aries in Eastern Cape, South Africa and an evaluation of current anthelmintic procedures [PDF]

, 2015
Humans have known about helminth infections since ancient times. Today half of the human population is plagued by a nematode infection. Nematodes are responsible for billions of dollars in global crop damage annually and have had devastating effects on ...
Rowell, Melyssa
core   +1 more source

Modelling the elimination of river blindness using long-term epidemiological and programmatic data from Mali and Senegal [PDF]

, 2017
The onchocerciasis transmission models EPIONCHO and ONCHOSIM have been independently developed and used to explore the feasibility of eliminating onchocerciasis from Africa with mass (annual or biannual) distribution of ivermectin within the timeframes ...
Basáñez, M-G, Bottomley, C, De Vlas, S J, Diawara, L, Dixon, M A, Stolk, W A, Traoré, M O, Walker, M   +7 more
core   +7 more sources

Efficacy and Safety of Ascending Dosages of Moxidectin and Moxidectin-albendazole Against Trichuris trichiura in Adolescents: A Randomized Controlled Trial

Clinical Infectious Diseases, 2019
Abstract Background Preventive chemotherapy is the main strategy to control soil-transmitted helminth (STH) infections. Albendazole and mebendazole are ubiquitously used, but they are not sufficiently effective against Trichuris trichiura.
Keller, Ladina, Palmeirim, Marta S., Ame, Shaali M., Ali, Said M., Puchkov, Maxim, Huwyler, Jörg, Hattendorf, Jan, Keiser, Jennifer   +7 more
openaire   +3 more sources

Moxidectin is a candidate for use as an in vivo internal standard in pharmacokinetic studies, as demonstrated with use in simultaneous tissue cage and ultrafiltration fluid collection

Frontiers in Veterinary Science
In vivo ultrafiltration has been used in veterinary pharmacokinetics since the early 2000’s as an improvement on the tissue cage model which enables sampling of fluids from extra-circulatory compartments.
Richard Munn, Richard Munn, Ted Whittem, Ted Whittem   +3 more
doaj   +1 more source

Treatment of Sarcoptic Mange in Wombats With Topical Moxidectin. [PDF]

Vet Med Sci
ABSTRACTSarcoptic mange is a debilitating disease affecting free‐living/wild bare‐nosed wombats (Vombatus ursinus). The disease causes thickening of the skin, pruritus, alopecia and deep fissures in the skin of infected animals, and ultimately death if left untreated.
Stannard HJ, Wynan MB, Wynan RJ, Cox A, Ralph H, Doran GS.   +5 more
europepmc   +4 more sources

Human infection with Gongylonema pulchrum [PDF]

, 1994
A 43 year old woman developed a painful tumor at the left buccal mucosa. Following local anti-inflammatory treatment a 35 mm long, living female adult worm of Gongylonema pulchrum was extracted from the affected side.
Jelinek, Thomas, Löscher, Thomas
core  

Problems in the control of nematode parasites of small ruminants in Malaysia [PDF]

, 2004
Nematode parasitic disease, attributed mainly Haemonchus contortus, is the greatest disease problem of small ruminants in Malaysia. This thesis comprises 6 studies on the emergence of anthelmintic resistance in these parasites, and how control may be ...
Panchadcharam, Chandrawathani
core