Results 131 to 140 of about 34,148 (221)
ABSTRACT The approval requirements in new regions that do not require domestic clinical data and the clinical data evaluation of multi‐regional clinical trials (MRCTs) and foreign clinical trials (FCTs) in the Japanese approval review processes for antimicrobial medicines were explored.
Rumiko Shimazawa, Masayuki Ikeda
wiley +1 more source
Renata Linertová,1,2 Rodrigo Abreu-González,3 Lidia García-Pérez,1,2 Marta Alonso-Plasencia,3 Luis Mateo Cordovés-Dorta,4 José Augusto Abreu-Reyes,4 Pedro Serrano-Aguilar2,5 1Fundación Canaria de ...
Serrano-Aguilar P +6 more
core
We report the synthesis of 21 novel thiazolidinedione–pyrazolopyrimidinone derivatives (12a–u), prepared by coupling thiazolidinedione and pyrazolopyrimidinone pharmacophores through various alkyl linkers. The compounds were characterized spectroscopically and evaluated against the Mtb H37Rv strain, identifying compounds 5c and 5d as potent ...
Pule Seboletswe +8 more
wiley +1 more source
Moxifloxacin Induced Acute Delirium with Visual Hallucinations
A few reports accuse and implicate moxifloxacin as a contributor to delirium state.Here, we report the A 60-year-old female patient, who developed acute delirium with visual hallucinations following treatment with moxifloxacin for atypical pneumonia ...
Asil Budakli +3 more
core +1 more source
Reactive Infectious Mucocutaneous Eruption (RIME): An Australian Case Series
ABSTRACT Whilst Reactive Infectious Mucocutaneous Eruption (RIME) displays a low mortality rate, the condition results in significant morbidity and resource allocation, including prolonged hospital admission. As such, early diagnosis and optimisation of treatment is imperative.
Hamish Moore +2 more
wiley +1 more source
Rongchang Chen1, Wenjiang Ma2, Xuezhong Yu3, Xinmin Liu4, Jihong Zhu5, Hong Liang6, Xiaomei Wu7, Tao Guo81State Key Laboratory of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, China; 2Respiratory Department, The First ...
Liu X +7 more
core
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITIES OF BIOINORGANIC COMPLEXES OF MOXIFLOXACIN.
Background: The growth of different organisms is controlled by drug-metal complexes which are injurious to humans. Moxifloxacin is one of the fourth generation fluoroquinolone antibiotics which inhibits DNA gyrase (a type II topoisomerase and ...
Fouzia Haider and Asia Naz. +1 more
core +1 more source
Therapeutic drug monitoring:How to improve moxifloxacin exposure in tuberculosis patients [PDF]
Tuberculosis is the world’s deadliest infectious disease, and, in particular the spread of multidrug-resistance is challenging the ending of the tuberculosis pandemic.
Pranger, Anna Diewerke
core +1 more source
ABSTRACT Background and Aims Fluoroquinolone exposure can give rise to drug‐induced liver injury. Genetic risk factors for this form of liver injury are poorly understood but some evidence suggests that HLA genes contribute. This study aimed to characterise HLA risk factors for fluoroquinolone‐induced liver injury in a European population. Methods From
Paola Nicoletti +10 more
wiley +1 more source
Multiphoton tissue imaging by using moxifloxacin
Multiphoton microscopy has been widely used for in-vivo tissue imaging of various biological studies. However, its application to clinical studies has been limited due to either lack of clinically compatible exogenous contrast agents or weak ...
Wang, Taejun +3 more
core

