Results 131 to 140 of about 34,148 (221)

An Evaluation of Foreign Clinical Data in the Approval Reviews of Antimicrobial Medicines in Japan: Considering Ethnic and Regional Differences in Data Extrapolations in Accordance With Regulatory Circumstances

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The approval requirements in new regions that do not require domestic clinical data and the clinical data evaluation of multi‐regional clinical trials (MRCTs) and foreign clinical trials (FCTs) in the Japanese approval review processes for antimicrobial medicines were explored.
Rumiko Shimazawa, Masayuki Ikeda
wiley   +1 more source

Intracameral cefuroxime and moxifloxacin used as endophthalmitis prophylaxis after cataract surgery: systematic review of effectiveness and cost-effectiveness

open access: yes, 2014
Renata Linertová,1,2 Rodrigo Abreu-González,3 Lidia García-Pérez,1,2 Marta Alonso-Plasencia,3 Luis Mateo Cordovés-Dorta,4 José Augusto Abreu-Reyes,4 Pedro Serrano-Aguilar2,5 1Fundación Canaria de ...
Serrano-Aguilar P   +6 more
core  

Thiazolidinedione–Pyrazolopyrimidinone Molecular Hybrids With Alkyl Spacers: Potential Antitubercular Agents Complemented by Molecular Modeling

open access: yesChemistrySelect, Volume 11, Issue 24, 25 June 2026.
We report the synthesis of 21 novel thiazolidinedione–pyrazolopyrimidinone derivatives (12a–u), prepared by coupling thiazolidinedione and pyrazolopyrimidinone pharmacophores through various alkyl linkers. The compounds were characterized spectroscopically and evaluated against the Mtb H37Rv strain, identifying compounds 5c and 5d as potent ...
Pule Seboletswe   +8 more
wiley   +1 more source

Moxifloxacin Induced Acute Delirium with Visual Hallucinations

open access: yes, 2015
A few reports accuse and implicate moxifloxacin as a contributor to delirium state.Here, we report the A 60-year-old female patient, who developed acute delirium with visual hallucinations following treatment with moxifloxacin for atypical pneumonia ...
Asil Budakli   +3 more
core   +1 more source

Reactive Infectious Mucocutaneous Eruption (RIME): An Australian Case Series

open access: yesAustralasian Journal of Dermatology, Volume 67, Issue 4, Page 241-246, June 2026.
ABSTRACT Whilst Reactive Infectious Mucocutaneous Eruption (RIME) displays a low mortality rate, the condition results in significant morbidity and resource allocation, including prolonged hospital admission. As such, early diagnosis and optimisation of treatment is imperative.
Hamish Moore   +2 more
wiley   +1 more source

Intravenous moxifloxacin in routine hospital treatment of respiratory tract infections in China: results of a multicenter, noninterventional study

open access: yes, 2011
Rongchang Chen1, Wenjiang Ma2, Xuezhong Yu3, Xinmin Liu4, Jihong Zhu5, Hong Liang6, Xiaomei Wu7, Tao Guo81State Key Laboratory of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, China; 2Respiratory Department, The First ...
Liu X   +7 more
core  

SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITIES OF BIOINORGANIC COMPLEXES OF MOXIFLOXACIN.

open access: yes, 2019
Background: The growth of different organisms is controlled by drug-metal complexes which are injurious to humans. Moxifloxacin is one of the fourth generation fluoroquinolone antibiotics which inhibits DNA gyrase (a type II topoisomerase and ...
Fouzia Haider and Asia Naz.   +1 more
core   +1 more source

Therapeutic drug monitoring:How to improve moxifloxacin exposure in tuberculosis patients [PDF]

open access: yes, 2018
Tuberculosis is the world’s deadliest infectious disease, and, in particular the spread of multidrug-resistance is challenging the ending of the tuberculosis pandemic.
Pranger, Anna Diewerke
core   +1 more source

HLA‐B*44 Alleles and HLA‐DQA1*03:01 as Genetic Risk Factors for Drug‐Induced Liver Injury due to Fluoroquinolones

open access: yesLiver International, Volume 46, Issue 6, June 2026.
ABSTRACT Background and Aims Fluoroquinolone exposure can give rise to drug‐induced liver injury. Genetic risk factors for this form of liver injury are poorly understood but some evidence suggests that HLA genes contribute. This study aimed to characterise HLA risk factors for fluoroquinolone‐induced liver injury in a European population. Methods From
Paola Nicoletti   +10 more
wiley   +1 more source

Multiphoton tissue imaging by using moxifloxacin

open access: yes, 2017
Multiphoton microscopy has been widely used for in-vivo tissue imaging of various biological studies. However, its application to clinical studies has been limited due to either lack of clinically compatible exogenous contrast agents or weak ...
Wang, Taejun   +3 more
core  

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