Results 1 to 10 of about 500 (180)

Intramammary Infusion of Micronised Purified Flavonoid Fraction (MPFF) in Mastitis-Diagnosed Dairy Cows Naturally Infected by Staphylococcus spp. in the Late Lactation [PDF]

Veterinary Sciences, 2023
Infectious mastitis is the most prevalent health problem in dairy cattle that can result in permanent economic losses on dairy farms. The micronised purified flavonoid fraction (MPFF) is a biocompatible active polyphenolic compound derived from flavonoid
Miguel A. Gutiérrez-Reinoso, José B. Uquilla, Jorge L. Guamaní, Ángel E. Caiza, Rocío P. Carrera, Manuel Garcia-Herreros   +5 more
doaj   +3 more sources

The efficacy of Aescin combined with MPFF for early control of bleeding from acute hemorrhoids, A randomized controlled trial

Asian Journal of Surgery
Background: Hemorrhoidal disease, affecting over 20 % of the population, presents management challenges due to its multifaceted nature. While treatments like Micronized Purified Flavonoid Fraction (MPFF) show promise, Aescin's efficacy remains uncertain.
Witcha Vipudhamorn, Pawit Sutharat, Suwan Sanmee   +2 more
exaly   +4 more sources

An international observational study assessing conservative management in hemorrhoidal disease: results of CHORALIS (aCute HemORrhoidal disease evALuation International Study) [PDF]

Journal of Comparative Effectiveness Research
Aim: Real-world evidence on the management of hemorrhoidal disease (HD) is limited. This international study collected clinical practice data on the effectiveness of conservative treatments for acute HD on symptoms and quality of life (QoL), providing ...
Philippe Godeberge, Zoltan Csiki, Mykhailo Zakharash, Elly Nyaim Opot, Yuri A Shelygin, Trung Tin Nguyen, Ashraf Amir, Ibrahima Konate, Moses Momoh, Joanna Chirol, Vanessa Blanc-Guillemaud, Ren Donglin   +11 more
doaj   +3 more sources

Adherence to Pharmacological Treatment in Chronic Venous Disease: Results of a Real-World, Prospective, Observational Cohort Study [PDF]

Life
Chronic venous disease (CVeD) affects millions of patients globally, being a multifactorial progressive condition that significantly impacts the quality of life of individuals.
Daciana Elena Branisteanu, Alice Elena Munteanu, Bogdan Mihai Dolofan, Elena Gabriela Popescu, Oana Vittos   +4 more
doaj   +3 more sources

Synergistic therapeutic approach for hemorrhoids: integrating mesenchymal stem cells with diosmin-hesperidin to target tissue edema and inflammation [PDF]

Archives of Medical Science
Introduction Mesenchymal stem cells (MSCs) have promising regenerative properties in tissue repair and anti-inflammatory responses. This study aimed to investigate the effects of MSCs and their combination with micronized purified flavonoid fraction ...
M. Hidayat Budi Kusumo, Adi Prayitno, Soetrisno ., Abdurahman Laqif   +3 more
doaj   +3 more sources

Efficacy of escin combined with micronized purified flavonoid fraction in controlling bleeding and preventing recurrence of acute internal hemorrhoids: a randomized controlled trial [PDF]

Annals of Coloproctology
Purpose Recurrence after initial control of acute internal hemorrhoidal bleeding remains a common and clinically relevant challenge. Escin, a venotonic and anti-inflammatory compound, may augment the therapeutic effects of micronized purified flavonoid ...
Witcha Vipudhamorn, Pawit Sutharat, Suwan Sanmee, Ekkarin Supatrakul, Sunhawit Junrungsee   +4 more
doaj   +2 more sources

Case Report: Micronized purified flavonoid fraction [Daflon]-induced bradycardia [PDF]

Frontiers in Pharmacology
IntroductionFlavonoids are oral venoactive drugs frequently prescribed to relieve the symptoms of chronic venous disorders. Micronized purified flavonoid fraction (MPFF, commercial Daflon 1000 mg) is a preparation that contains mainly diosmin and a small
Jhennyfer Aline Lima Rodrigues, Jonathas Pereira das Graças, Gledson de Oliveira Machado   +2 more
doaj   +2 more sources

A Molecular–Protein Fusion Framework for Rapid Virtual Screening: Accelerating Lead Discovery for “Undruggable’’ Oncogenic Targets [PDF]

Pharmaceuticals
Background/Objectives: KRAS G12D is one of the most frequent oncogenic mutations in pancreatic ductal adenocarcinoma (PDAC) and remains challenging to target because of its limited druggable binding pockets. This study aimed to develop a machine learning-
Chenxi Zhou, Yanni Zhu, Chenrui Yang, Yu Gao, Jianyang Lu, Dengming Ming   +5 more
doaj   +2 more sources

Effectiveness of Conservative Treatment on Chronic Venous Disease Symptoms and Quality of Life in Patients with Type 2 Diabetes: Results from a Subanalysis of the VEIN STEP Observational Study [PDF]

Vascular Health and Risk Management
Jorge Hernando Ulloa,1 Zoubida Tazi Mezalek,2 Alejandro José González Ochoa,3 Faezeh Hosseini Sadrabadi,4 Vanessa Blanc-Guillemaud,4 Jean-Christophe Philips,5 Toni Feodor6 1Department of Vascular Surgery, Santa Fe de Bogotá Foundation, University of the ...
Ulloa JH, Tazi Mezalek Z, González Ochoa AJ, Hosseini Sadrabadi F, Blanc-Guillemaud V, Philips JC, Feodor T   +6 more
doaj   +2 more sources

Multimodal Inertial–Visual Sensor Fusion over Evolutionary Deep Temporal Modeling for Humanoid Movement Recognition: A Benchmark Study Toward Sports Telerehabilitation [PDF]

Bioengineering
Wearable inertial sensing and markerless vision are increasingly integrated to enable objective assessment of locomotor and postural function for sports telerehabilitation, intelligent physiotherapy, and athlete performance monitoring.
Mohammad Shorfuzzaman, Muhammad Hanzla, Bayan Alabdullah, Mohammed Alonazi, Jasem Almotiri, Ahmad Jalal   +5 more
doaj   +2 more sources