Results 81 to 90 of about 69,250 (228)

Plasma Elastase Screening in Hematological Disease Reveals Its Potential as a Diagnostic and Prognostic Biomarker in Hematological Malignancies

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction Neutrophil‐extracellular traps are net‐like material released by triggered neutrophils and composed of decondensed chromatin linked to nuclear proteins. Elastase, one of the fourth most represented neutrophil‐specific serine proteases stored in azurophil granules of naïve neutrophils, exerts various actions, including degradation ...
Pasqualina Scala   +14 more
wiley   +1 more source

Immunophenotypic, Genetic, and Clinical Features Associated With RUNX1 Mutation in Acute Leukemias and Chronic Myeloid Neoplasms

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction RUNX1 is a commonly mutated transcriptional regulator of hematopoiesis in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Mutated RUNX1 (mRUNX1) may associate with cross‐lineage immunophenotypic aberrancy, presenting potential complications for blast lineage assignment at diagnosis. Methods Clinical and laboratory
Yi Han Xia, Eric McGinnis
wiley   +1 more source

Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis

open access: yesJournal of Integrative Plant Biology, EarlyView.
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia   +12 more
wiley   +1 more source

Perceived Stress Scale: Psychometric Validation in Spanish University Nursing Students and Applications for Mental Health

open access: yesJournal of Psychiatric and Mental Health Nursing, EarlyView.
ABSTRACT Background Nursing students—including those specializing in mental health and psychiatric care—as well as practicing psychiatric nurses frequently experience elevated levels of psychological stress. Such stress can adversely affect their academic performance, overall well‐being, and future professional development.
Pedro García‐Martínez   +7 more
wiley   +1 more source

Highly Polygenic Control of Photosynthetic Responses to Nighttime Temperature Studied by Genomic Prediction

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Rising nighttime temperature (Tnight) can reduce crop yields while low Tnight may restrict plant growth and development. Despite quantifiable effects of Tnight, genetic basis underlying plant responses to Tnight remains unclear. We investigated natural variation in long‐term response of effective photosynthetic efficiency (Fq’/Fm’) to Tnight ...
Ana Carolina dos Santos Sá   +5 more
wiley   +1 more source

Engineered surface strategies to manage dental implant‐related infections

open access: yesPeriodontology 2000, EarlyView.
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza   +7 more
wiley   +1 more source

Myeloproliferative Neoplasien (MPN)

open access: yes, 2012
ZusammenfassungDas Kapitel 4 beinhaltet eine Zusammenstellung der am Universitätsklinikum Freiburg verwendeten Tumortherapie- und ggf. Studien-Protokolle der Entität Myeloproliferative Neoplasien (MPN). Dieses ist in die Unterkapitel Chronische Myeloische Leukämie (CML), Polycythemia Vera (PV), Essentielle Thrombozythämie (ET) und Myelofibrose (MF ...
Monika Engelhardt   +2 more
openaire   +1 more source

Outcomes of patients with de novo and secondary acute myeloid leukaemia treated with front‐line hypomethylating agents and venetoclax: A retrospective Italian study

open access: yes
British Journal of Haematology, EarlyView.
Ilaria Tanasi   +14 more
wiley   +1 more source

Policy Narratives and Empowerment: Implementation of the Swedish National Violence Prevention Program

open access: yesPolicy Studies Journal, EarlyView.
ABSTRACT As the Narrative Policy Framework (NPF) begins to unpack issues of power and narratives, the main focus has been on power‐over and domination rather than more transformative notions of power‐to and empowerment. This article draws on insights from gender and policy studies and suggests that the NPF benefits from adopting a multifaceted notion ...
Hilda Broqvist
wiley   +1 more source

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