Results 61 to 70 of about 41,337 (280)

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

Advanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng, Jian Song, Yuxin Li, Ming Chen, Zeshen Liang, Binyao Qiu, Xuemin Liu, Xuetao Shi, Yong Fan   +8 more
wiley   +1 more source

Identification of a Novel <i>KRAS::ETNK1</i> Fusion Transcript in a Myelodysplastic/Myeloproliferative Overlap Syndrome With Eosinophilia: A Case Report. [PDF]

EJHaem
ABSTRACT This work describes, to our knowledge, the first reported case of a patient with an MDS/MPN overlap syndrome harboring a novel KRAS::ETNK1 fusion transcript. The disease initially presented with eosinophilia, megakaryocyte expansion, mast cell infiltration, and a background of typical MDS/MPN‐associated mutations (ASXL1, TET2, EZH2, BCOR, and ...
Caledec M, Labussière-Wallet H, Fontaine J, Larcher M, Barraco F, Balsat M, Daull AM, Gross Z, Helluin J, Loron S, Gilis L, Ducastelle-Lepretre S, Fossard G, Heiblig M, Sujobert P, Fontaine M, Hayette S, Alcazer V.   +17 more
europepmc   +2 more sources

Cluster analysis of inflammatory gene expression in MPN patients.

, 2019
(A) Hierarchical clustering separates MF grade 0–1 MPN from MF grade 2–3 MPN in a training cohort of 76 patients. (B) K-means clustering (k = 4) separates prefibrotic (MF grade 0–1) disease from overtly fibrotic disease (MF grade 2–3). Four clusters with
Olga Pozdnyakova (3585275), Michele Baltay (6685274), Annaliese Getz (6685277), Waihay J. Wong (6685271), Robert P. Hasserjian (6685283), Kit Fuhrman (6685280), Jon C. Aster (201399)   +6 more
core   +1 more source

A Metal‐Polyphenol Self‐Assembled Coated 3D Sponge With Mild Photothermal Antibacterial, Exudate‐Controlling, and Immunomodulatory Functions for Hemostasis and Chronic Wound Healing

Advanced Science, EarlyView.
A thrombin‐functionalized copper‐polydopamine nanofiber sponge integrates rapid hemostasis, mild photothermal antibacterial therapy, stimulus‐responsive Cu2+ release, chemodynamic oxidative stress, and macrophage immunomodulation. This multifunctional dressing suppresses infection, regulates inflammation, promotes angiogenesis and re‐epithelialization,
Ziwei Zhang, Feng Qin, Xiaomeng Zhang, Xueqin Shuang, Jiahua Zhou, Ming Cheng, Baicheng Lu, Mingyue Song, Yuntian Bai, Dianying Zhang, Ming Li, Yanhua Wang   +11 more
wiley   +1 more source

Improve The Microbiological Quality of Groundwater Around Bonoloyo Cemetery by Boiling

Quagga
Public cemeteries are considered to be a potential source of groundwater pathogen contamination. Many settlements in Indonesia are located near cemeteries and rely on groundwater for consumption.
Elvina Sophia Ranti, Maurisa Yuant Khairani, Triastuti Rahayu   +2 more
doaj   +1 more source

Characterization of disease-propagating stem cells responsible for myeloproliferative neoplasm–blast phase

JCI Insight, 2022
Chronic myeloproliferative neoplasms (MPN) frequently evolve to a blast phase (BP) that is almost uniformly resistant to induction chemotherapy or hypomethylating agents.
Xiaoli Wang, Raajit K. Rampal, Cing Siang Hu, Joseph Tripodi, Noushin Farnoud, Bruce Petersen, Michael R. Rossi, Minal Patel, Erin McGovern, Vesna Najfeld, Camelia Iancu-Rubin, Min Lu, Andrew Davis, Marina Kremyanskaya, Rona Singer Weinberg, John Mascarenhas, Ronald Hoffman   +16 more
doaj   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Prevalence of Escherichia coli and Coliform Contamination in Unbranded Refillable Drinking Water Depots in Rural South Lampung, Indonesia: A Case Study around ITERA

Journal of Applied Food Technology
Drinking water is an important aspect for the body in sustaining life. In Indonesia, the refillable drinking water depot business is now growing rapidly and has an important meaning in providing drinking water that is easily accessible to the community ...
Ade Alifa Mutiara Marchy, Syahrizal Nasution, Yosi Syafitri   +2 more
doaj   +1 more source

The possible role of mutated endothelial cells in myeloproliferative neoplasms

Haematologica, 2021
Myeloproliferative neoplasms (MPN) are chronic, clonal hematologic malignancies characterized by myeloproliferation and a high incidence of vascular complications (thrombotic and bleeding).
Mirko Farina, Domenico Russo, Ronald Hoffman   +2 more
doaj   +1 more source

Closing the gap: genetic landscape of MPN [PDF]

Blood, 2016
In this issue of Blood, Milosevic Feenstra et al1 and Cabagnols et al2 report the discovery of heterogeneous novel mutations in MPL and JAK2 genes in 5% to 10% of essential thrombocythemia (ET) and primary myelofibrosis (PMF) patients who lacked what are regarded as classical mutations in these myeloproliferative neoplasms (MPNs) and were thereby ...
Harrison, Claire N., VANNUCCHI, ALESSANDRO MARIA   +1 more
openaire   +3 more sources