Results 51 to 60 of about 41,337 (280)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
International Medical Case Reports Journal, 2023 Abdu Mohammed,1 Abate Bane Shewaye,1,2 Fozia Abdela,1,2 Zebeaman Tibebu Gorfu,1 Ahmed Adem1,2 1Department of Internal Medicine, Adera Medical Center, Addis Ababa, Ethiopia; 2Department of internal Medicine, Addis Ababa University, College of Health ...
Mohammed A +4 more
doaj
JAK2 in Myeloproliferative Neoplasms: Still a Protagonist
Pharmaceuticals, 2022 The discovery of the activating V617F mutation in Janus kinase 2 (JAK2) has been decisive for the understanding of myeloproliferative neoplasms (MPN).
Michael Stephan Bader +1 more
doaj +1 more source
Advanced Science, EarlyView.. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source
Бюллетень сибирской медицины, 2021 Aim. To study the content of cytokines in the blood serum of patients with obstructive jaundice of gallstone origin before and after surgical treatment, depending on the development of postoperative complications.Materials and methods.
O. V. Smirnova, N. G. Elmanova
doaj +1 more source
Advanced Science, EarlyView.Liquid gallium (Ga) acts as a catalytic center for nitric oxide (NO) generation within a tannic acid–zirconium metal–phenolic network coating. Stabilized Ga nanoparticles catalyze S‐nitrosothiol decomposition through surface electron transfer, enabling controlled NO production, enhancing endothelial biocompatibility, and providing antioxidant and anti ...
Franco Centurion +10 more
wiley +1 more source
Targets in MPNs and potential therapeutics
, 2022 Philadelphia-negative classical Myeloproliferative Neoplasms (MPNs), including Polycythemia Vera (PV), Essential Thrombocythemia (ET) and Primary Myelofibrosis (PMF), are clonal hemopathies that emerge in the hematopoietic stem cell (HSC) compartment.
Levy, Gabriel +6 more
openaire +3 more sources
Independent validation of MPN subgroups by cluster analysis.
, 2019 (A) Hierarchical clustering separates MF grade 0–1 MPN from MF grade 2–3 MPN in a test cohort of 32 patients. (B) K-means clustering (k = 4) separates prefibrotic (MF grade 0–1) disease from overtly fibrotic disease (MF grade 2–3) into four clusters ...
Olga Pozdnyakova (3585275) +6 more
core +1 more source
Advanced Science, EarlyView.An injectable gelatin‐based tannic acid–iron hydrogel with mild photothermal therapy could not only induce immunogenic cell death, but also elicit ferroptosis of both tumor cells and tumor‐associated macrophages, resulting in DC maturation, T‐cell infiltration and down‐regulation of ferroptosis‐sensitive M2‐type TAMs levels.
Yuan Zhu +10 more
wiley +1 more source
Scientific Reports, 2021 A subset of essential thrombocythemia (ET) cases are negative for disease-defining mutations on JAK2, MPL, and CALR and defined as triple negative (TN). The lack of recurrent mutations in TN-ET patients makes its pathogenesis ambiguous. Here, we screened
Tadaaki Inano +15 more
doaj +1 more source