Results 51 to 60 of about 36,802 (283)

Cell-autonomous megakaryopoiesis associated with polyclonal hematopoiesis in triple-negative essential thrombocythemia

Scientific Reports, 2021
A subset of essential thrombocythemia (ET) cases are negative for disease-defining mutations on JAK2, MPL, and CALR and defined as triple negative (TN). The lack of recurrent mutations in TN-ET patients makes its pathogenesis ambiguous. Here, we screened
Tadaaki Inano, Marito Araki, Soji Morishita, Misa Imai, Yoshihiko Kihara, Maho Okuda, Yinjie Yang, Masafumi Ito, Satoshi Osaga, Hiroyuki Mano, Yoko Edahiro, Tomonori Ochiai, Kyohei Misawa, Yasutaka Fukuda, Jun Ando, Norio Komatsu   +15 more
doaj   +1 more source

The possible role of mutated endothelial cells in myeloproliferative neoplasms

Haematologica, 2021
Myeloproliferative neoplasms (MPN) are chronic, clonal hematologic malignancies characterized by myeloproliferation and a high incidence of vascular complications (thrombotic and bleeding).
Mirko Farina, Domenico Russo, Ronald Hoffman   +2 more
doaj   +1 more source

Liquid Gallium Nanozyme Coatings Enable Sustained Nitric Oxide Generation With Antioxidant and Anti‐Inflammatory Functions

Advanced Science, EarlyView.
Liquid gallium (Ga) acts as a catalytic center for nitric oxide (NO) generation within a tannic acid–zirconium metal–phenolic network coating. Stabilized Ga nanoparticles catalyze S‐nitrosothiol decomposition through surface electron transfer, enabling controlled NO production, enhancing endothelial biocompatibility, and providing antioxidant and anti ...
Franco Centurion, Kang Lin, Shu Geng, Siti Nur Asyura Adzlan, Qingqing Fan, Federico Mazur, Ravindra Kokate, Priyank Kumar, Christina Cortez‐Jugo, Frank Caruso, Rona Chandrawati   +10 more
wiley   +1 more source

Improve The Microbiological Quality of Groundwater Around Bonoloyo Cemetery by Boiling

Quagga
Public cemeteries are considered to be a potential source of groundwater pathogen contamination. Many settlements in Indonesia are located near cemeteries and rely on groundwater for consumption.
Elvina Sophia Ranti, Maurisa Yuant Khairani, Triastuti Rahayu   +2 more
doaj   +1 more source

Characterization of disease-propagating stem cells responsible for myeloproliferative neoplasm–blast phase

JCI Insight, 2022
Chronic myeloproliferative neoplasms (MPN) frequently evolve to a blast phase (BP) that is almost uniformly resistant to induction chemotherapy or hypomethylating agents.
Xiaoli Wang, Raajit K. Rampal, Cing Siang Hu, Joseph Tripodi, Noushin Farnoud, Bruce Petersen, Michael R. Rossi, Minal Patel, Erin McGovern, Vesna Najfeld, Camelia Iancu-Rubin, Min Lu, Andrew Davis, Marina Kremyanskaya, Rona Singer Weinberg, John Mascarenhas, Ronald Hoffman   +16 more
doaj   +1 more source

Mutation Profile in BCR-ABL1-Negative Myeloproliferative Neoplasms: A Single-Center Experience From India

Hematology/Oncology and Stem Cell Therapy, 2022
Objective/Background: Recurrent somatic mutations in the JAK2, calreticulin (CALR), and the MPL genes are described as drivers of BCR-ABL1-negative myeloproliferative neoplasms (MPN) that includes polycythemia vera (PV), essential thrombocytosis (ET ...
Madhavi Maddali, Uday Prakash Kulkarni, Niveditha Ravindra, Arun Kumar Arunachalam, Arvind Venkatraman, Sharon Lionel, Marie Therese Manipadam, Anup J. Devasia, Anu Korula, N.A. Fouzia, Aby Abraham, Alok Srivastava, Biju George, Poonkuzhali Balasubramanian, Vikram Mathews   +14 more
doaj   +1 more source

不同培养基对湖泊氨氧化细菌MPN计数的影响 [PDF]

, 2008
本文研究了培养时间、培养基类型、硫酸铵浓度对湖泊沉积物与水中氨氧化细菌(AOB)MPN计数的影响。结果表明,MPN值随培养时间的延长而增大,且趋于稳定。对不同样品而言,培养40d后,MSF培养基均给出稳定的MPN值。在3种不同类型的培养基(XZ-AOB、MSF、SW)中,MSF产生的MPN值最大。此外,培养基中的硫酸铵浓度对MPN计数亦有重要影响,与沉积物AOB相比 ...
邱珊莲, 周易勇
core  

Programmed Interfacial Phase Separation for Spatiotemporal Fungicide Delivery via Tunable Micro/Nano Architectures

Advanced Science, EarlyView.
ABSTRACT Translating dynamic liquid‐liquid phase separation into robust solid‐state architectures remains a challenge in materials engineering. Here, we report a composition‐driven interfacial assembly strategy that couples supramolecular coacervation with metal‐phenolic coordination to engineer tunable fungicide carriers.
Rui Zhang, Tongfang Jing, Leiming He, Kaidi Cui, Yuying Song, Xuewei Mao, Lidong Cao, Lin Zhou   +7 more
wiley   +1 more source

Prevalence of Escherichia coli and Coliform Contamination in Unbranded Refillable Drinking Water Depots in Rural South Lampung, Indonesia: A Case Study around ITERA

Journal of Applied Food Technology
Drinking water is an important aspect for the body in sustaining life. In Indonesia, the refillable drinking water depot business is now growing rapidly and has an important meaning in providing drinking water that is easily accessible to the community ...
Ade Alifa Mutiara Marchy, Syahrizal Nasution, Yosi Syafitri   +2 more
doaj   +1 more source

Thrombosis and hemorrhage in myeloproliferative neoplasms: The platelet perspective

Platelets, 2022
Classical myeloproliferative neoplasm (MPN), also known as BCR-ABL-negative MPN, is a clonal disease characterized by abnormal expansion of hematopoietic stem cells.
Yiming Feng, Yue Zhang, Jialan Shi
doaj   +1 more source