Results 31 to 40 of about 69,250 (228)
Targets in MPNs and potential therapeutics
, 2022 Philadelphia-negative classical Myeloproliferative Neoplasms (MPNs), including Polycythemia Vera (PV), Essential Thrombocythemia (ET) and Primary Myelofibrosis (PMF), are clonal hemopathies that emerge in the hematopoietic stem cell (HSC) compartment.
Levy, Gabriel +6 more
openaire +3 more sources
Advanced Materials Interfaces, EarlyView.Hair keratin fibers inevitably deteriorate under UV exposure, heat, and dryness. A robust composite coating assembles delaminated Ti3C2 MXene nanosheets onto keratin surfaces through biocompatible metal‐polyphenol networks of EGCG. This hybrid layer simultaneously screens UV, dissipates heat, reinforces mechanical strength, suppresses static charge ...
Juyeon Kang +8 more
wiley +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Advanced Science, EarlyView.Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Integer-valued polynomials over matrices and divided differences
, 2013 Let $D$ be an integrally closed domain with quotient field $K$ and $n$ a positive integer. We give a characterization of the polynomials in $K[X]$ which are integer-valued over the set of matrices $M_n(D)$ in terms of their divided differences.
Peruginelli, Giulio
core +3 more sources
Closing the gap: genetic landscape of MPN [PDF]
Blood, 2016 In this issue of Blood, Milosevic Feenstra et al1 and Cabagnols et al2 report the discovery of heterogeneous novel mutations in MPL and JAK2 genes in 5% to 10% of essential thrombocythemia (ET) and primary myelofibrosis (PMF) patients who lacked what are regarded as classical mutations in these myeloproliferative neoplasms (MPNs) and were thereby ...
Harrison, Claire N. +1 more
openaire +3 more sources
Advanced Science, EarlyView.Considering the great challenge in Glioblastoma multiforme (GBM) treatment, the authors designed and synthesized a multifunctional nanoplatform that effectively induced ferroptosis by synergetically inhibiting intrinsic intrisinc anti‐ferroptosis proteins, GPX4 & DHODH, and realized excellent in vitro and in vivo anti‐GBM effect.
Guodong Ren +12 more
wiley +1 more source
NH Department of Environmental Services Shellfish Program Activities, January 2006 – December 2006 [PDF]
, 2007 This report summarizes the activities of the NH Department of Environmental Services (NHDES) Shellfish Program for the period of January 2006 to December 2006, emphasizing those tasks for which NHDES received direct funding from the NH Estuaries Project.
Nash, Chris, Wood, Matt
core +1 more source
Advanced Science, EarlyView.A multifaceted chemical strategy, integrating bacterial tropism, metal‐ion interference therapy, and immunotherapy, resulted in significant tumor regression in murine models. A pioneering paradigm for the design of biohybrid materials was established, highlighting how sophisticated chemical engineering of living systems can unlock new avenues for ...
Tingting Zhang +7 more
wiley +1 more source
Evolution of Feedback Loops in Oscillatory Systems [PDF]
, 2009 Feedback loops are major components of biochemical systems. Many systems show multiple such (positive or negative) feedback loops. Nevertheless, very few quantitative analyses address the question how such multiple feedback loops evolved.
Hafner, M., Koeppl, H., Wagner, A.
core +2 more sources
QUANTIFICATION OF LISTERIA MONOCYTOGENES IN MILK BY MPN-PCR AND MPN-CULTURE METHODS [PDF]
Journal of microbiology, biotechnology and food sciences, 2014 The aim of this study was to compare the MPN-PCR (Most Probable Number- Polymerase Chain Reaction) and MPN-Culture methods in enumerating of Listeria monocytogenes in milk. In order to compare the accuracy of these methods, 103 cell/ml Listeria monocytogenes and different background bacteria which may be present in raw milk, were inoculated in ...
Mahzad Hosseini +2 more
openaire +1 more source