Results 11 to 20 of about 41,337 (280)

CLASSIFICATION OF MPN

Hematology, Transfusion and Cell Therapy
The 2022 updated 5th edition of the World Health Organization Classification of myeloproliferative neoplasms and mastocytosis focused on changes in the rationale behind the classification, combined morphologic, immunophenotypic, molecular, and ...
Haifa Kathrin Al-Ali
doaj   +2 more sources

The Hen or the Egg: Inflammatory Aspects of Murine MPN Models [PDF]

Mediators of Inflammation, 2015
It has been known for some time that solid tumors, especially gastrointestinal tumors, can arise on the basis of chronic inflammation. However, the role of inflammation in the genesis of hematological malignancies has not been extensively studied. Recent
Jonas S. Jutzi, Heike L. Pahl
doaj   +2 more sources

C097 | MDS/MPN OTHER THAN CMML: AN ITALIAN COOPERATIVE STUDY

Haematologica
Background: MDS/MPN syndromes include chronic myelomonocytic leukemia (CMML), MDS/MPN with neutrophilia or atypical chronic myeloid leukemia (aCML), MDS/MPN neoplasm with SF3B1 mutation and thrombocytosis (-SF3B1) and MDS/MPN not otherwise specified ...
L. Guarnera, A. Di Veroli, M. Santopietro, G. Iaquinta, A.L. Biagi, S. Leonetti Crescenzi, C. Tatarelli, R. Latagliata, P. Grammatico, S. Mariani, A. Piccioni, M. Riva, L. Rizzo, P. Salutari, G. Albanese, F. Iovene, A. Molteni, F. Catania, B. Fattizzo, A. Andriani, K. Paciaroni, M. Breccia, E. Fabiani, M.T. Voso, L. Maurillo   +24 more
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Genomics of MPN progression [PDF]

Hematology, 2020
Abstract The Philadelphia chromosome–negative (Ph−) myeloproliferative neoplasms (MPNs) are a heterogenous group of hematopoietic stem cell diseases characterized by activated JAK/STAT signaling and a variable propensity toward myelofibrotic and leukemic transformation.
Anand A, Patel, Olatoyosi, Odenike
openaire   +2 more sources

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy [PDF]

Advanced science
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Xin Y, Chen S, Huang S, Huang M, Zhu J, Wang Z, Shen J, Zheng Q.   +7 more
europepmc   +2 more sources

Bleeding complications in bcr-abl negative myeloproliferative neoplasms (MPN): a retrospective single-center study of 829 MPN patients

, 2021
Wille K, Huenerbein K, Jagenberg E, et al. Bleeding complications in bcr-abl negative myeloproliferative neoplasms (MPN): a retrospective single-center study of 829 MPN patients. European Journal of Haematology.
Fuchs, Christiane ; https://orcid.org/, Kai Wille, Vera Kolatzki, Tatjana Becker, Marchi, Hannah ; https://orcid.org/, Ellen Jagenberg, Griesshammer, Martin, Karlo Huenerbein, Wille, Kai, Huenerbein, Karlo, Sadjadian, Parvis, Martin Griesshammer, Meixner, Raphael, Kolatzki, Vera, Raphael Meixner, Hannah Marchi, Christiane Fuchs, Jagenberg, Ellen, Becker, Tatjana, Parvis Sadjadian, Wille, K., Huenerbein, K., Fuchs, C., Meixner, R., Marchi, H., Jagenberg, E., Becker, T., Sadjadian, P., Kolatzki, V., Griesshammer, M.   +29 more
core   +2 more sources

MDS/MPN-Unclassifiable with t(X;17)(q28;q21) and KANSL1-MTCP1/CMC4 Fusion Gene [PDF]

, 2021
Myelodysplastic/myeloproliferative neoplasm, unclassifiable (MDS/MPN-U) is a poorly characterized entity among overlap myeloid syndromes. Recent studies have shown heterogeneous mutational profiles in this group being able to subclassify them into ...
Molony, Peter, Selvarajah, Shamini, Sakhdari, Ali, Smith, Adam C, Ali Sakhdari, Peter Molony, Shamini Selvarajah, Adam C. Smith   +7 more
core   +1 more source

Proliferative activity is disturbed in myeloproliferative neoplasms (MPN), myelodysplastic syndrome (MDS), andMDS/MPNdiseases. Differences betweenMDSandMDS/MPN

, 2021
The proliferation marker Ki-67 is widely used within the field of diagnostic histopathology as a prognostic marker for solid cancers. However, Ki-67 is hardly used for prognostic and diagnostic purposes in flow cytometric analyses of hematologic ...
Roosmarie J. M. Drent, Stefan G. C. Mestrum, Mestrum, Stefan G. C., Anton H. N. Hopman, Leers, Math P. G., de Wit, Norbert C. J., Frans C. S. Ramaekers, Hopman, Anton H. N., Norbert C. J. de Wit, Math P. G. Leers, Drent, Roosmarie J. M., Ramaekers, Frans C. S.   +11 more
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Morphology of myelodysplastic/myeloproliferative neoplasms (MDS/MPN) [PDF]

, 2019
Dijagnostička kategorija mijelodisplastične/mijeloproliferativne neoplazme (MDS/MPN) obuhvaća klonske hematopoetske neoplazme koje u vrijeme postavljanja dijagnoze istodobno pokazuju klinička, laboratorijska i/ili morfološka obilježja i ...
Kardum-Skelin, Ika, Kaić, Gordana, Pažur, Marina, Mandac Rogulj, Inga, Šunjić Stakor, Mia, Katalenić Simon, Suzana, Jelić Puškarić, Biljana, Ostojić Kolonić, Slobodanka, Radić Krišto, Delfa   +8 more
core   +1 more source

The ABNL-MARRO 001 study: a phase 1–2 study of randomly allocated active myeloid target compound combinations in MDS/MPN overlap syndromes

, 2022
BackgroundMyelodysplastic/myeloproliferative neoplasms (MDS/MPN) comprise several rare hematologic malignancies with shared concomitant dysplastic and proliferative clinicopathologic features of bone marrow failure and propensity of acute leukemic ...
Lübbert, Michael, Moyo, Tamara K., Savona, Michael R., MDS/MPN International Working Group, [Study group]   +3 more
core   +1 more source