Results 1 to 10 of about 22,378 (120)
Novel Therapies in Myeloproliferative Neoplasms: Beyond JAK Inhibitor Monotherapy [PDF]
Journal of Immunotherapy and Precision Oncology, 2021 Myeloproliferative neoplasms (MPNs) are clonal hematopoietic disorders that consist classically of polycythemia vera (PV), essential thrombocythemia (ET), and myelofibrosis (MF).
Sophia S. Lee +2 more
doaj +1 more source
Antibiotics, 2021 Healthcare workers’ (HCW) clothing has been shown to harbor multidrug-resistant bacteria (MDRB) and may contribute to transmission. The aim of this study was to evaluate presence of MDRB on HCW uniforms in Cyprus.
Pavlina Lena +6 more
doaj +1 more source
Passer Journal, 2021 This study was designed to determine the extent of contamination of water storage tanks by non-lactose fermenter Enterobacter spp, and to characterize the chlorine and antibiotic resistance status.
Hastyar H. Najmuldeen
doaj +1 more source
A JAK of all trades: how global phosphoproteomics reveal the Achilles heel of MPNs
Molecular & Cellular Oncology, 2021 While Janus-kinase (JAK)-inhibitors effectively reduce the inflammatory phenotype of myeloproliferative neoplasms (MPN), they do not affect disease burden or presence of the mutated clone to a major extent. Here, we show how Janus-kinase 2 (JAK2)-mutated
Tina M. Schnoeder +2 more
doaj +1 more source
Chronic Myelomonocytic Leukemia: Hematopathology Perspective [PDF]
Journal of Immunotherapy and Precision Oncology, 2021 Our understanding of chronic myelomonocytic leukemia (CMML) has evolved tremendously over the past decade. Large-scale sequencing studies have led to increased insight into the genomic landscape of CMML and clinical implications of these changes. This in
Siba El Hussein +4 more
doaj +1 more source
Assessment of the quality of drinking water of Halabja City-Iraqi Kurdistan [PDF]
Kirkuk Journal of Science, 2015 The quality of drinking water is a crucial factor for human health. The objective of this study was to assess the physicochemical and biological characteristics of the various sources of drinking water in the city of Halabja, Iraqi Kurdistan. Forty water
Attallah O. Kasem +3 more
doaj +1 more source
CALR-ETdb, the database of calreticulin variants diversity in essential thrombocythemia
Platelets, 2022 Essential thrombocythemia (ET) is a blood cancer defined by a strong increase of platelet numbers. A quarter of patients suffering from ET show mutations in the last exon of calreticulin (CALR) gene.
Nora El Jahrani +2 more
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Detcetion Of Bacterial Contamination Of Drinking Water In The Right Side Of Mosul City By Multiple Tubes Fermentation Technique. [PDF]
مجلة التربية والعلم, 2019 This study aimed to investigate bacterial contamination of drinking water in the right side of Mosul city using multiple tubes fermentation technique, depending on total coliform count as an indicator, this study takes seven months started from December,
Adeba AL-Nuaaman, Musaab Al- Ballo
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JAK2/STAT5 Pathway Mutation Frequencies in South African BCR/ABL Negative MPN Patients
Hematology/Oncology and Stem Cell Therapy, 2023 Background: Mutations in JAK2/STAT5 proliferation pathway genes are key in the diagnosis of myeloproliferative neoplasms (MPNBCR/ABLneg), with JAK2V617F being found in 50-97% of MPNBCR/ABLneg subtypes.
Karen L. Shires +4 more
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Mouse models of myeloproliferative neoplasms for pre-clinical testing of novel therapeutic agents
Biomedical Papers, 2021 Myeloproliferative neoplasms (MPN), are clonal hematopoietic stem cell (HSC) disorders driven by gain-of-function mutations in JAK2 (JAK2-V617F), CALR or MPL genes.
Jan Stetka, Radek C. Skoda
doaj +1 more source