Results 51 to 60 of about 6,085 (208)

Diagnostic approaches for monkeypox virus

iLABMED
Mpox (formerly Monkeypox) is a zoonotic infection caused by Monkeypox virus (MPXV). Since 2022, Mpox epidemics have occurred in many non‐endemic countries and regions, leading the World Health Organization to declare a public health emergency of ...
Guohao Fan, Jiahua Kuang, Shengjie Zhang, Yang Yang, Yingxia Liu, Hongzhou Lu   +5 more
doaj   +1 more source

In Silico Design and Computational Characterization of Novel Chimeric Multiepitope Antigens for Mpox Serosurveillance: An Immunoinformatics Approach

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims The Monkeypox (Mpox) virus is a zoonotic Orthopoxvirus with a global outbreak that began in 2022, with more than 132,000 confirmed cases and 1500 deaths across over 128 countries. The pandemic preparedness pipeline emphasizes the importance of diagnostic surveillance of pathogens in at‐risk populations to monitor ...
Roland Ngwese Akwelle, Robert Adamu Shey, Mary Teke Efeti, Lekeayi Nelson Acha, Gordon Takop Nchanji, Yanick Aqua Stong Tangan, Joan Amban Chick, Ntang Emmaculate Yaah, Lahngong Methodius Shinyuy, Cabirou Mounchili Shintouo, Bernis Neneyoh Yengo, Abey Blessings Ayuk, Junior Ekunidi Engarimbi, Ketura Yaje Gwei, Brinate Teke Tebo, Derrick Neba Nebangwa, Beltine Muyer Tamnjong, Luc Vanhamme, Jacob Souopgui, Vincent P. K. Titanji, Stephen Mbigha Ghogomu   +20 more
wiley   +1 more source

The Mpox vaccine (JYNNEOS vaccine) [PDF]

Mpox (formerly known as monkeypox) is caused by a virus that is closely related to the virus that causes smallpox. JYNNEOS is a 2-dose vaccine that was developed to protect against both mpox and smallpox.

core   +3 more sources

Therapeutic Poxviruses Induce the Secretion of Immunostimulating and Anti‐Tumoral Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 6, June 2026.
Immune cells infected by therapeutic poxviruses release increased amounts of extracellular vesicles bearing viral proteins and therapeutic payloads. Such EVs have the ability to activate a CD8+ T‐cell mediated antitumoral immune response and decrease tumor growth.
Lucas Walther, Vincent Mittelheisser, Marie‐Christine Claudepierre, Louis Bochler, Magali Rompais, Jules Deforges, Nathalie Silvestre, Annabel Larnicol, Christine Carapito, Eric Quémeneur, Jacky G Goetz, Karola Rittner, Vincent Hyenne   +12 more
wiley   +1 more source

Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Sola Akinbolade, Rhiannon Potter, Alex Inskip, Jane Nesworthy, Kirsti Brock, Gill Norman   +5 more
wiley   +1 more source

Machine Learning‐Augmented Loop‐Mediated Isothermal Amplification‐Enabled Point‐of‐Care for Mpox‐Specific Detection

Advanced Intelligent Systems, Volume 8, Issue 5, May 2026.
A low‐cost, portable point‐of‐care platform for rapid Mpox detection using loop‐mediated isothermal amplification is reported. The device integrates fluorescence readout and mobile monitoring. A machine‐learning model analyzes temperature data and correlates thermal changes with DNA concentration, enabling sensitive and reliable molecular diagnosis in ...
Nazente Atceken, Ahmed Choukri Abdullah, Olgac Ozarslan, Ziya Yıldız, Savas Tasoglu   +4 more
wiley   +1 more source

Monkeypox frequently asked questions [PDF]

Monkeypox is a rare disease caused by infection with the monkeypox virus. Monkeypox virus is part of the same family of viruses as smallpox. Monkeypox symptoms are similar to smallpox symptoms, but milder, and monkeypox is rarely fatal.Monkeypox was ...

core   +9 more sources

A bivalent Mpox nanoparticle vaccine induces robust immune response and provides long-lasting protection against vaccinia virus challenge

Emerging Microbes and Infections
The 2022 and 2024 monkeypox (mpox) outbreak highlighted the urgent need for effective, durable, and safe vaccines. In addition to the traditional smallpox vaccines that could bring cross-protection against mpox, mRNA and protein-subunit mpox vaccines ...
Yanhai Wang, Hao Sun, Huixu Zhou, Wenxue Yang, Sha Li, Mengchan Hao, Haiyan Chang, Yuan Zhang, Yun Wang, Jianjun Chen   +9 more
doaj   +1 more source

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus

Animal Models and Experimental Medicine, Volume 9, Issue 5, Page 1047-1055, May 2026.
This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li, Ziqing Jia, Zhe Cong, Jianrong Ma, Jiahan Lu, Yongzhi Hou, Fei Wang, Jiasen Yang, Ting Chen, Jingjing Zhang, Dong Zhang, Jing Xue   +11 more
wiley   +1 more source

Self-reported Infection Status, Knowledge and Associated Factors of Monkeypox Among Men Who Have Sex with Men in Jiaxing, China

BMC Public Health
Background As of September 2023, more than 1,000 cases of monkeypox (mpox) have been reported in China. Based on the available evidence, men who have sex with men (MSM) are at high risk for mpox infection.
Yangyang Tian, Zhigang Hou, Guoying Zhu, Qianqian Zhang, Wutong Zhu, Hao Feng, Weizhe Pan, Qiang Li, Rui Ge, Zhongwen Chen   +9 more
doaj   +1 more source