Results 1 to 10 of about 5,325 (169)

Pathogenicity and contact transmissibility of clade IIb MPXV in African dormice

Emerging Microbes and Infections
The global outbreak of monkeypox virus (MPXV) in 2022 raised widespread scientific concern regarding potential changes in its biological characteristics.
Changbo Ou, Zongzheng Zhao
exaly   +3 more sources

Rapid, sensitive, and highly specific detection of monkeypox virus by CRISPR-based diagnostic platform

Frontiers in Public Health, 2023
BackgroundMonkeypox (MPX), caused by the Monkeypox virus (MPXV), has incurred global attention since it broke out in many countries in recent times, which highlights the need for rapid and reliable diagnosis of MPXV infection.MethodsWe combined ...
Lin Gong, Xiaomin Chen, Yimei Wang, Jiansheng Liang, Xiaoli Liu, Yi Wang   +5 more
doaj   +1 more source

Monkeypox virus-infected individuals mount comparable humoral immune responses as Smallpox-vaccinated individuals

Nature Communications, 2023
In early 2022, a cluster of monkeypox virus (MPXV) infection (mpox) cases were identified within the UK with no prior travel history to MPXV-endemic regions.
Ashley D. Otter, Scott Jones, Bethany Hicks, Daniel Bailey, Helen Callaby, Catherine Houlihan, Tommy Rampling, Nicola Claire Gordon, Hannah Selman, Panayampalli S. Satheshkumar, Michael Townsend, Ravi Mehta, Marcus Pond, Rachael Jones, Deborah Wright, Clarissa Oeser, Simon Tonge, Ezra Linley, Georgia Hemingway, Tom Coleman, Sebastian Millward, Aaron Lloyd, Inger Damon, Tim Brooks, Richard Vipond, Cathy Rowe, Bassam Hallis   +26 more
doaj   +1 more source

Comparison of monkeypox viruses pathogenesis in mice by in vivo imaging. [PDF]

PLoS ONE, 2009
Monkeypox viruses (MPXV) cause human monkeypox, a zoonotic smallpox-like disease endemic to Africa, and are of worldwide public health and biodefense concern. Using viruses from the Congo (MPXV-2003-Congo-358) and West African (MPXV-2003-USA-044) clades,
Jorge E Osorio, Keith P Iams, Carol U Meteyer, Tonie E Rocke   +3 more
doaj   +1 more source

Development of multi-epitope vaccines against the monkeypox virus based on envelope proteins using immunoinformatics approaches

Frontiers in Immunology, 2023
BackgroundSince May 2022, cases of monkeypox, a zoonotic disease caused by the monkeypox virus (MPXV), have been increasingly reported worldwide. There are, however, no proven therapies or vaccines available for monkeypox.
Caixia Tan, Caixia Tan, Fei Zhu, Fei Zhu, Fei Zhu, Fei Zhu, Fei Zhu, Pinhua Pan, Pinhua Pan, Pinhua Pan, Pinhua Pan, Pinhua Pan, Anhua Wu, Anhua Wu, Chunhui Li, Chunhui Li   +15 more
doaj   +1 more source

Determination of seroprevalence and kinetics of humoral response using mpox virus A29 protein

Communications Medicine, 2023
Background Mpox virus (MPXV), previously known as monkeypox virus, has spread globally in 2022. An accurate and convenient antibody test is essential for the determination of seroprevalence and for studying immune response after natural infection or ...
Jian-Piao Cai, Wing-Ming Chu, Anthony Raymond Tam, Kun Wang, Yuting Han, Lin-Lei Chen, Xiaojuan Zhang, Charlotte Yee-Ki Choi, Vincent Chi-Chung Cheng, Kwok-Hung Chan, Zhiwei Chen, Ivan Fan-Ngai Hung, Carol Ho-Yan Fong, Kelvin Kai-Wang To   +13 more
doaj   +1 more source

Evaluation of the diagnostic performance of a commercial molecular assay for the screening of suspected monkeypox cases in Sri Lanka

Infectious Medicine, 2023
Background: The main objective of the present study was to compare the diagnostic performance of the commercial LightMix Modular Monkeypox Virus (MPXV) qPCR (TIB Molbiol, Germany) assay with the in-house nonvariola orthopox/monkeypox generic real-time ...
H.B.C. Harshani, G.A. Liyanage, D.V.R.G. Ruwan, U.K.I.U. Samaraweera, J.I. Abeynayake   +4 more
doaj   +1 more source

Monkeypox: epidemiological situation, diagnostics, prevention, new challenges and problems of our time [PDF]

Клиническая микробиология и антимикробная химиотерапия
Monkeypox (mpox) is a particularly dangerous zoonotic infectious disease, the causative agent of which belongs to the numerous family Poxviridae, subfamily Chordopoxvirinae, genus Orthopoxvirus and belongs to the I pathogenicity group; genetically close ...
Belyakova E.N., Shipulin G.A.
doaj   +1 more source

Monkey pox [PDF]

Hospital Pharmacology
Introduction: The endemic monkeypox virus (MPXV) is a double-stranded DNA virus that is a member of the Orthopoxviral genus of the Poxviridae family. The viruses proliferate quickly and enter the bloodstream, where they cause viremia, which subsequently ...
Hoque Majedul M.
doaj   +1 more source

Evaluation of Cross-Immunity to the Mpox Virus Due to Historic Smallpox Vaccination

Vaccines, 2023
When the Mpox virus (MPXV) began spreading globally in 2022, it became critical to evaluate whether residual immunity from smallpox vaccination provided cross-protection.
Giulia Matusali, Elisa Petruccioli, Eleonora Cimini, Francesca Colavita, Aurora Bettini, Eleonora Tartaglia, Settimia Sbarra, Silvia Meschi, Daniele Lapa, Massimo Francalancia, Licia Bordi, Valentina Mazzotta, Sabrina Coen, Klizia Mizzoni, Alessia Beccacece, Emanuele Nicastri, Luca Pierelli, Andrea Antinori, Enrico Girardi, Francesco Vaia, Alessandro Sette, Alba Grifoni, Delia Goletti, Vincenzo Puro, Fabrizio Maggi   +24 more
doaj   +1 more source