Results 31 to 40 of about 5,325 (169)

Role of Direct Sexual Contact in Human Transmission of Monkeypox Virus, Italy

Emerging Infectious Diseases
The 2022 global mpox outbreak was driven by human-to-human transmission, but modes of transmission by sexual relationship versus sexual contact remain unclear. We evaluated sexual transmission of mpox by using monkeypox virus (MPXV) G2R-mRNA as a marker
Giuseppe Sberna, Gabriella Rozera, Claudia Minosse, Licia Bordi, Valentina Mazzotta, Alessandra D’Abramo, Enrico Girardi, Andrea Antinori, Fabrizio Maggi, Eleonora Lalle   +9 more
doaj   +1 more source

Laboratory Investigations of African Pouched Rats (Cricetomys gambianus) as a Potential Reservoir Host Species for Monkeypox Virus. [PDF]

PLoS Neglected Tropical Diseases, 2015
Monkeypox is a zoonotic disease endemic to central and western Africa, where it is a major public health concern. Although Monkeypox virus (MPXV) and monkeypox disease in humans have been well characterized, little is known about its natural history, or ...
Christina L Hutson, Yoshinori J Nakazawa, Joshua Self, Victoria A Olson, Russell L Regnery, Zachary Braden, Sonja Weiss, Jean Malekani, Eddie Jackson, Mallory Tate, Kevin L Karem, Tonie E Rocke, Jorge E Osorio, Inger K Damon, Darin S Carroll   +14 more
doaj   +1 more source

Performance of a Novel Real-Time PCR-Based Assay for Rapid Monkeypox Virus Detection in Human Samples

Microorganisms, 2023
The ongoing epidemic of mpox, namely human monkeypox virus (MPXV) infection, requires rapid and reliable laboratory diagnosis. We report on the QIAstat-Dx viral vesicular panel PCR assay that allows the detection of (within 75 min) six vesicular disease ...
Flora Marzia Liotti, Simona Marchetti, Federico Falletta, Sara D’Onghia, Maurizio Sanguinetti, Rosaria Santangelo, Brunella Posteraro   +6 more
doaj   +1 more source

Data_Sheet_1_Development of a specific MPXV antigen detection immunodiagnostic assay.docx

, 2023
Human monkeypox (mpox) has recently become a global public health emergency; however, assays that detect mpox infection are not widely available, largely due to cross-reactivity within the Orthopoxvirus genus. Immunoassay development was largely confined
Jay W. Hooper, Christopher P. Stefan (6083399), Janice A. Williams, Ian Davis (271288), Keersten M. Ricks, Jackie M. Payne, Madison P. Sanders, Jackie M. Payne (16953150), Victoria L. Olguin (16953153), Madison P. Sanders (16953156), Tamara Clements (16953159), John W. Huggins, Janice A. Williams (6842360), Eric M. Mucker, Christopher P. Stefan, Ian Davis, John W. Huggins (202153), Victoria L. Olguin, Jay W. Hooper (8803886), Keersten M. Ricks (7435337), Tamara Clements, Eric M. Mucker (13788577)   +21 more
core   +1 more source

Atypical Varicella‐Like Presentation of an Imported Mpox Case in Austria Confirmed to be Infected With Clade Ib

JEADV Clinical Practice, EarlyView.
ABSTRACT The recent upsurge of cases caused by the newly identified Clade Ib monkeypox virus (MPXV) in the Democratic Republic of the Congo and other countries has emerged as a significant public health concern. A 34‐year‐old male tourist from Venezuela presented in Vienna, Austria, during his travels through Europe with fever, pharyngitis and an ...
Amélie Hampel, David N. Springer, Jeremy V. Camp, Stephan W. Aberle, Maximilian Egg, Luigi Segagni Lusignani, Katharina Grabmeier‐Pfistershammer, Robert Strassl, Judith Wendt, Tamar Kinaciyan, Alessandra Handisurya   +10 more
wiley   +1 more source

Necropsy Findings from MPXV infected prairie dogs.

, 2013
Transmissibility of MPXV was studied within the prairie dog MPXV model. For each study, eight cages with holes on one side were utilized to individually cross-house eight animals.
Cody Clemmons (193946), Johanna S. Salzer (193957), Darin S. Carroll (193931), Christine M. Hughes (193951), Kevin L. Karem (193972), Inger K. Damon (190329), Christina L. Hutson (193929), Victoria A. Olson (193962), Nadia Gallardo-Romero (193934), Tamas Nagy (184820)   +9 more
core   +1 more source

Complete Genome Sequence Analysis of the First Imported Mpox Virus Clade Ib Variant in China

Pathogens
Mpox, a zoonotic disease caused by the mpox virus (MPXV), has seen a significant shift in its epidemiological status since 2022, evolving from an initial local outbreak to a global epidemic. This recent outbreak of MPXV mainly emerged in several European
Yin Song, Yong Yan, Jingyu Xu, Shencong Lv, Ganglin Ren, Yamei Zhou, Wanchen Song, Rui Ge, Peihua Xu, Guoying Zhu, Zhongwen Chen   +10 more
doaj   +1 more source

Two‐Dimensional Materials For Lateral Flow Assays: A Critical Review of Functional Roles and Translational Challenges

VIEW, EarlyView.
2D nanosheets, with large surface area, excellent optical/electrical properties, and high specificity, combine with lateral flow assay strips to enable rapid, readable detection, boosting the strips’ development and applications. Abstract Lateral flow assays (LFAs) are widely used for point‐of‐care diagnostics, but their detection capability remains ...
Weimin Xu, Ruping Liu, Na Gao, Jianxiao Zhu, Haowen Jiang, Shouzheng Jiao, Zhicheng Sun, Kai Shen, Gaolian Xu, Minghua Du, Ziyan Li, Yang Wang   +11 more
wiley   +1 more source

Genomic Epidemiology and Clinical Characteristics of Mpox Lineage C.1 Outbreak in Thailand, 2023–2024

Journal of Medical Virology, Volume 98, Issue 9, September 2026.
ABSTRACT Since 2022, human monkeypox virus (hMPXV) has emerged in non‐endemic regions, including Thailand. However, the genomic dynamics and clinical correlates of local transmission remain incompletely defined. Whole‐genome sequencing was performed on hMPXV from 16 patients in Thailand (2023–2024) using targeted amplicon NGS.
Kamol Suwannakarn, Chutikarn Chaimayo, Atsadang Boonmee, Charussri Leeyaphan, Pattriya Jirawattanadon, Pravarit Athiprayoon, Natsada Saengdao, Piyarat Taiphakphaibun, Chutima Deetippasert, Warinya Nuwong, Niracha Athipanyasilp, Archiraya Pattama, Navin Horthongkham   +12 more
wiley   +1 more source

Construction of MPXV-Luc+viruses.

, 2013
A) Two synthetic DNA fragments containing the p7.5 promoter from vaccinia were annealed and cloned into the pUC18 plasmid, resulting into the pPCSII, plasmid. B) The GPT gene was PCR amplified and cloned into the pTK/Sel2 plasmid resulting in the pTK-GPT
Jorge E. Osorio (211899), Carol U. Meteyer (157786), Keith P. Iams (371232), Tonie E. Rocke (351855)   +3 more
core   +1 more source