Results 31 to 40 of about 4,135 (173)

Current and Perspective Sensing Methods for Monkeypox Virus

Bioengineering, 2022
The outbreak of the monkeypox virus (MPXV) in non-endemic countries is an emerging global health threat and may have an economic impact if proactive actions are not taken.
Ijaz Gul, Changyue Liu, Xi Yuan, Zhicheng Du, Shiyao Zhai, Zhengyang Lei, Qun Chen, Muhammad Akmal Raheem, Qian He, Qiuyue Hu, Chufan Xiao, Zhang Haihui, Runming Wang, Sanyang Han, Ke Du, Dongmei Yu, Can Yang Zhang, Peiwu Qin   +17 more
doaj   +1 more source

Clinical case of cavernitis — complicated monkeypox infection

Инфекция и иммунитет
The article presents a clinical case of monkeypox (MPOX) infection, a rare acute viral zoonosis until 2022, previously endemic in Africa, but currently recorded worldwide, including Europe and Bulgaria.
E. D. Lyutsova, I. G. Radeva, K. N. Nikolova, K. B. Karaivanov, D. M. Radkova, M. D. Gospodinova   +5 more
doaj   +1 more source

Diagnosis and Assessment of Monkeypox Virus (MPXV) Infection by Quantitative PCR Assay: Differentiation of Congo Basin and West African MPXV Strains

Japanese Journal of Infectious Diseases, 2008
Human monkeypox, an infectious disease caused by monkeypox virus (MPXV), is endemic to western and central Africa. A LightCycler quantitative PCR (LC-qPCR) system was developed for the diagnosis of this disease, targeting the A-type inclusion body gene (ATI gene) of MPXV.
Saijo, Masayuki, Ami, Yasushi, Suzaki, Yuriko, Nagata, Noriyo, Iwata, Naoko, Hasegawa, Hideki, Ogata, Momoko, Fukushi, Shuetsu, Mizutani, Tetsuya, Iizuka, Itoe, Sakai, Koji, Sata, Tetsutaro, Kurata, Takeshi, Kurane, Ichiro, Morikawa, Shigeru   +14 more
openaire   +2 more sources

Laboratory Investigations of African Pouched Rats (Cricetomys gambianus) as a Potential Reservoir Host Species for Monkeypox Virus. [PDF]

PLoS Neglected Tropical Diseases, 2015
Monkeypox is a zoonotic disease endemic to central and western Africa, where it is a major public health concern. Although Monkeypox virus (MPXV) and monkeypox disease in humans have been well characterized, little is known about its natural history, or ...
Christina L Hutson, Yoshinori J Nakazawa, Joshua Self, Victoria A Olson, Russell L Regnery, Zachary Braden, Sonja Weiss, Jean Malekani, Eddie Jackson, Mallory Tate, Kevin L Karem, Tonie E Rocke, Jorge E Osorio, Inger K Damon, Darin S Carroll   +14 more
doaj   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Performance of a Novel Real-Time PCR-Based Assay for Rapid Monkeypox Virus Detection in Human Samples

Microorganisms, 2023
The ongoing epidemic of mpox, namely human monkeypox virus (MPXV) infection, requires rapid and reliable laboratory diagnosis. We report on the QIAstat-Dx viral vesicular panel PCR assay that allows the detection of (within 75 min) six vesicular disease ...
Flora Marzia Liotti, Simona Marchetti, Federico Falletta, Sara D’Onghia, Maurizio Sanguinetti, Rosaria Santangelo, Brunella Posteraro   +6 more
doaj   +1 more source

Risk of Monkeypox virus (MPXV) transmission through the handling and consumption of food

Microbial Risk Analysis, 2022
Monkeypox (MPX) is a zoonotic infectious disease caused by Monkeypox virus (MPXV), an enveloped DNA virus belonging to the Poxviridae family and the Orthopoxvirus genus. Since early May 2022, a growing number of human cases of Monkeypox have been reported in non-endemic countries, with no history of contact with animals imported from endemic and ...
Chaix, Estelle, Boni, Mickaël, Guillier, Laurent, Bertagnoli, Stéphane, Mailles, Alexandra, Collignon, Catherine, Kooh, Pauline, Ferraris, Olivier, Martin-Latil, Sandra, Manuguerra, Jean-Claude, Haddad, Nadia   +10 more
openaire   +4 more sources

Role of Direct Sexual Contact in Human Transmission of Monkeypox Virus, Italy

Emerging Infectious Diseases
The 2022 global mpox outbreak was driven by human-to-human transmission, but modes of transmission by sexual relationship versus sexual contact remain unclear. We evaluated sexual transmission of mpox by using monkeypox virus (MPXV) G2R-mRNA as a marker
Giuseppe Sberna, Gabriella Rozera, Claudia Minosse, Licia Bordi, Valentina Mazzotta, Alessandra D’Abramo, Enrico Girardi, Andrea Antinori, Fabrizio Maggi, Eleonora Lalle   +9 more
doaj   +1 more source

An In Silico Analysis of PCR-Based Monkeypox Virus Detection Assays: A Case Study for Ongoing Clinical Surveillance

Viruses, 2023
The 2022 global Mpox outbreak swiftly introduced unforeseen diversity in the monkeypox virus (MPXV) population, resulting in numerous Clade IIb sublineages.
Kuncheng Song, Hayden N. Brochu, Qimin Zhang, Jonathan D. Williams, Lakshmanan K. Iyer   +4 more
doaj   +1 more source

Atypical Varicella‐Like Presentation of an Imported Mpox Case in Austria Confirmed to be Infected With Clade Ib

JEADV Clinical Practice, EarlyView.
ABSTRACT The recent upsurge of cases caused by the newly identified Clade Ib monkeypox virus (MPXV) in the Democratic Republic of the Congo and other countries has emerged as a significant public health concern. A 34‐year‐old male tourist from Venezuela presented in Vienna, Austria, during his travels through Europe with fever, pharyngitis and an ...
Amélie Hampel, David N. Springer, Jeremy V. Camp, Stephan W. Aberle, Maximilian Egg, Luigi Segagni Lusignani, Katharina Grabmeier‐Pfistershammer, Robert Strassl, Judith Wendt, Tamar Kinaciyan, Alessandra Handisurya   +10 more
wiley   +1 more source