Results 51 to 60 of about 5,325 (169)
Identification of Repurposed Drugs Against Monkeypox Virus Through Comprehensive Virtual Screening
Graphical Abstract and Lay Summary By combining interspecies protein analysis with advanced virtual screening, this study identifies potent repurposed drug candidates—including vindesine and LY2090314—targeting mpox DNA topoisomerase and polymerase. This workflow provides a rapid, practical framework for antiviral discovery against emerging infectious ...
Taeho Yu, Woo Dae Jang, Sang Yup Lee
wiley +1 more source
MPXV197 is required for T cell inhibition by MPXV.
A)Left Panel: PBMC from VACV-immune subjects (n = 4) were infected with VACV, MPXV Zaire or MPXV US2003 (MOI of 0.5) for 18 h. Poxvirus-specific CD4+ and CD8+ T cell responses were measured by ICCS.
Erin Meermeier (564752) +18 more
core +1 more source
Robust Adaptive Immunity to MPXV in Older People Who Received Childhood Vaccinia Vaccination [PDF]
Monkeypox virus (MPXV) is a zoonotic Orthopoxvirus responsible for Monkeypox (Mpox), historically associated with sporadic zoonotic transmission but increasingly characterised by sustained human-to-human spread.
Olmo, Paula +9 more
core +3 more sources
Evaluation of Poxvirus-Specific Antibody Response in Monkey Poxvirus-Negative and -Positive Cohorts
Objectives: Understanding the antibody response in monkeypox virus (MPXV)-infected and uninfected individuals is essential for developing next-generation MPXV vaccines.
Nannan Jia +17 more
doaj +1 more source
Severe Scrotal Cellulitis in a Young Man
JEADV Clinical Practice, EarlyView.
Hamad El Hajj +3 more
wiley +1 more source
Immuno-histochemical staining in tissues of mice infected with MPXV.
Tissues from 4-wk-old SCID/BALB/c mice infected IP with MPXV-USA-2003-Luc+and uninfected SCID/BALB/c mice were stained by using vaccinia mouse hyperimmune mouse and horse-radish peroxidase as a detection label.
Jorge E. Osorio (211899) +3 more
core +1 more source
Diagnostic approaches for monkeypox virus
Mpox (formerly Monkeypox) is a zoonotic infection caused by Monkeypox virus (MPXV). Since 2022, Mpox epidemics have occurred in many non‐endemic countries and regions, leading the World Health Organization to declare a public health emergency of ...
Guohao Fan +5 more
doaj +1 more source
Evolutionary Analysis and Antiviral Drug Prediction of Mpox Virus
The resurgence of mpox virus (MPXV) poses a significant challenge to global public health. Currently, there is a limited understanding of the evolutionary details of MPXV during its epidemics, and no specific drugs have been developed for it.
Zhong-Hao Lian +3 more
doaj +1 more source
Associations of presumptive risk factors for MPXV infection and demographics.
Associations of presumptive risk factors for MPXV infection and demographics.
Emile Okitolonda (439976) +11 more
core +1 more source

