Results 71 to 80 of about 4,135 (173)

Nano‐Silver‐Selenium Liquid Dressing Facilitates Treatment of Monkeypox and Prevention of Viral Transmission in a Surrogate Mouse Model

Exploration, Volume 6, Issue 3, June 2026.
There is no effective method to treat this virus and prevent its transmission. To address this, we have developed a nano‐silver‐selenium liquid dressing (AgSe@LD) by combining silver and selenium nanoparticles with commercial liquid dressings. This unique AgSe@LD formulation exhibits good adhesion, stability and toughness and demonstrates efficient ...
Wei Wang, Mengjun Li, Zining Liu, Jiayin Chen, Ke Liu, Fengfang Wei, Junrui Li, Yixuan Xie, Yushan Jiang, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Minghui Yang, Hua Ma, Ruilin Zhang, Chenguang Shen, Yuhui Liao   +15 more
wiley   +1 more source

Mpox virus OPG175 negatively regulates viral replication by controlling Wnt signaling

iScience
Summary: Mpox virus (MPXV) infection exhibits different case fatality rates and symptoms depending on its clade. However, there has been insufficient molecular biological analysis of the differences between clades.
Yoshitaka Nakata, Masako Yamasaki, Yukio Watanabe, Keiya Uriu, Rina Hashimoto, Takuya Yamamoto, Kei Sato, Akatsuki Saito, Kazuo Takayama   +8 more
doaj   +1 more source

A Global Health Alert on the Re‐Emergence of Mpox a Viral Zoonotic Illness Its Prevention and Management: A Narrative Review

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Monkeypox virus (MPXV) is gaining attention in the global health community due to its potential for human transmission and similarities to the well‐known smallpox virus. Mpox was first detected in the 1970s and mostly affects Central and West Africa.
Muslim Bin Aqeel, Asif Hanif, Shahzad Ahmad, Fatima Iftikhar Shah, Benish Javed, Shazia Iqbal   +5 more
wiley   +1 more source

Mpox virus poxin-schlafen fusion protein suppresses innate antiviral response by sequestering STAT2

Emerging Microbes and Infections
Mpox virus (MPXV) has to establish efficient interferon (IFN) antagonism for effective replication. MPXV-encoded IFN antagonists have not been fully elucidated.
Pearl Chan, Zi-Wei Ye, Wenlong Zhao, Chon-Phin Ong, Xiao-Yu Sun, Pak-Hin Hinson Cheung, Dong-Yan Jin   +6 more
doaj   +1 more source

A retrospective genomic characterisation of the 2022 mpox outbreak in Belgium, and in vitro assessment of three antiviral compoundsResearch in context

EBioMedicine
Summary: Background: Since the beginning of May 2022, cases of mpox have been reported in several European and American countries where the disease is nonendemic. We performed a retrospective genomic characterisation of the 2022 mpox outbreak in Belgium,
Tony Wawina-Bokalanga, Bert Vanmechelen, Anne-Sophie Logist, Mandy Bloemen, Lies Laenen, Sébastien Bontems, Marie-Pierre Hayette, Cécile Meex, Christelle Meuris, Catherine Orban, Emmanuel André, Robert Snoeck, Guy Baele, Samuel L. Hong, Graciela Andrei, Piet Maes   +15 more
doaj   +1 more source

Applying improved ddPCR to reliable quantification of MPXV in clinical settings

Microbiology Spectrum
ABSTRACT Monkeypox virus (MPXV) poses a global health threat. Droplet digital PCR (ddPCR) holds potential as an accurate diagnostic tool for clinical microbiology. However, there is limited literature on the applicability of ddPCR in clinical settings.
Chudan Liang, Huiqin Yang, Xiaofeng Yang, Zhenyu Long, Yuandong Zhou, Jian Wang, Linjin Fan, Mou Zeng, Yulong Wang, Haipeng Zheng, Zequn Wang, Pengfei Ye, Jingyan Lin, Wendi Shi, Hongxin Huang, Huijun Yan, Jun Qian, Linghua Li, Linna Liu   +18 more
openaire   +3 more sources

Modelling the potential spread of Clade Ib MPXV in Asian cities

BMJ Public Health
Background The ongoing 2023–2024 mpox outbreak in several African countries, driven by the novel Clade Ib strain, has resulted in imported cases being reported in Sweden, Thailand and India. The potential high transmissibility of this new strain and shifts in transmission modes may make territories in Asia ...
Shihui Jin, Gregory Gan, Akira Endo, Kiesha Prem, Rayner Kay Jin Tan, Jue Tao Lim, Keisuke Ejima, Borame L Dickens   +7 more
openaire   +3 more sources

MPXV DNA kinetics in bloodstream and other body fluids samples

Scientific Reports
Abstract Since spring 2022, the global epidemiology of the monkeypox virus (MPXV) has changed. The unprecedented increase of human clade II MPXV cases worldwide heightened concerns about this emerging zoonotic disease. We analysed the positivity rates, viral loads, infectiousness, and persistence of MPXV DNA for up to 4 months in ...
Meschi S, Colavita F, Carletti F, Mazzotta V, Matusali G, Specchiarello E, Ascoli Bartoli T, Mondi A, Minosse C, Giancola ML, Pinnetti C, Valli MB, Lapa D, Mizzoni K, Sullivan DJ, Ou J, Focosi D, Girardi E, Nicastri E, Antinori A, Maggi F.   +20 more
openaire   +4 more sources

Characterization of a plant-derived monoclonal antibody targeting extracellular enveloped virions of Monkeypox virus

Frontiers in Plant Science
In 2022, the global outbreak of monkeypox virus (MPXV) with increased human-to-human transmission triggered urgent public health interventions. Plant-derived monoclonal antibodies (mAbs) are being explored as potential therapeutic strategies due to their
Jennifer A. Melendez, Jennifer A. Melendez, Haiyan Sun, James Bonner, James Bonner, Qiang Chen, Qiang Chen   +6 more
doaj   +1 more source

Bivalent single-domain antibodies show potent mpox virus neutralization through M1R antigen

Communications Biology
Despite the recent mpox outbreak raising global concerns, no fully validated antiviral treatment exists, highlighting the urgent need for effective therapeutics.
Daisuke Akazawa, Masayuki Shimojima, Eun-Sil Park, Akiko Okutani, Milagros Virhuez-Mendoza, Yusuke Inoue, Takayuki Hishiki, Ken Maeda, Hideki Ebihara, Yoshimasa Takahashi, Koichi Watashi   +10 more
doaj   +1 more source