Results 1 to 10 of about 1,043,937 (210)

A comprehensive review of monkeypox virus and mpox characteristics [PDF]

Frontiers in Cellular and Infection Microbiology
Monkeypox virus (MPXV) is the etiological agent of monkeypox (mpox), a zoonotic disease. MPXV is endemic in the forested regions of West and Central Africa, but the virus has recently spread globally, causing outbreaks in multiple non-endemic countries ...
Emmanuel Alakunle, Daniel Kolawole, Diana Diaz-Cánova, Faith Alele, Oyelola Adegboye, Ugo Moens, Malachy Ifeanyi Okeke   +6 more
doaj   +5 more sources

Modeling the transmission dynamics of Mpox virus. [PDF]

Sci Rep
The global emergence of human monkeypox (Mpox) necessitates stage-structured transmission models. We develop a compartmental framework with Prodromal, Rash, and Complication stages, identifying critical thresholds through bifurcation analysis. A transcritical bifurcation at [Formula: see text] day[Formula: see text] separates stable disease-free ...
Rabiu S, Ali MKM.
europepmc   +4 more sources

Pathogenicity and transmissibility of Mpox virus in African dormice. [PDF]

Microbiol Spectr
ABSTRACT The global spread of Mpox virus (MPXV) poses a major public health challenge, yet reliable and consistent animal models for MPXV evaluation remain limited, which hinders progress in developing treatment strategies and transmission-blocking technologies.
Chen Z, Zhang L, Li L, Shao M, Zhao Z, Shang C, Liu Z, Liu J, Liu Y, Li X, Guo Z.   +10 more
europepmc   +3 more sources

Viable mpox virus in the environment of a patient room

International Journal of Infectious Diseases, 2023
We conducted a prospective environmental surveillance study to investigate the air, surface, dust, and water contamination of a room occupied by a patient infected with mpox virus (MPXV) at various stages of the illness. The patient tested positive for MPXV from a throat swab and skin lesions. Environmental sampling was conducted in a negative pressure
Shawn Vasoo, Sophie Octavia, Kalisvar Marimuthu   +2 more
exaly   +7 more sources

Mpox virus detection in the wastewater and the number of hospitalized patients in the Poznan metropolitan area, Poland

International Journal of Infectious Diseases, 2023
Objectives: Wastewater-based epidemiology can determine the scale of a mpox epidemic and thus is a promising additional tool that can complete data gathered by the clinical monitoring approach and predict more accurately the development and progress of ...
Monika Gazecka, Jakub Sniezek, Krzysztof Maciolek, Arleta Kowala-Piaskowska, Pawel Zmora   +4 more
doaj   +3 more sources

Evaluating the susceptibility of various common cell lines and assessing inactivation conditions to Mpox virus [PDF]

Microbiology Spectrum
Over the past decade, numerous infectious diseases have emerged. In 2022, the World Health Organization declared the Mpox outbreak a global public health emergency, as the virus spread rapidly to over 107 countries.
Shu-Chen Hsu, Ping-Cheng Liu, Shan-Ko Tsai, An-Yu Chen, Hui-Ping Tsai, Jun-Ren Sun, Ti-Yu Li, Pei-Yu Hsieh, Jyh-Yuan Yang, Tein-Yao Chang   +9 more
doaj   +2 more sources

Wastewater analysis of Mpox virus in a city with low prevalence of Mpox disease: an environmental surveillance studyResearch in context

The Lancet Regional Health. Americas, 2023
Summary: Background: Tracking infectious diseases at the community level is challenging due to asymptomatic infections and the logistical complexities of mass surveillance. Wastewater surveillance has emerged as a valuable tool for monitoring infectious
Jeremiah Oghuan, Carlos Chavarria, Scout R. Vanderwal, Anna Gitter, Akpevwe Amanda Ojaruega, Carlos Monserrat, Cici X. Bauer, Eric L. Brown, Sara Javornik Cregeen, Jennifer Deegan, Blake M. Hanson, Michael Tisza, Hector I. Ocaranza, John Balliew, Anthony W. Maresso, Janelle Rios, Eric Boerwinkle, Kristina D. Mena, Fuqing Wu   +18 more
doaj   +4 more sources

Urological Manifestation of Mpox Virus: A Scoping Review. [PDF]

Res Rep Urol
Mpox primarily presents with systemic and cutaneous symptoms. However, it can also lead to urological complications, necessitating specialized attention. The aim of this scoping review is to summarize the current evidence regarding the urological manifestations of Mpox, possible complications, and available treatments.An electronic systematic search of
Mantica G, Drocchi G, Chierigo F, Granelli G, Trani G, Paraboschi I, Alba S, Ambrosini F, De Klerk C, Riccardi N, Nozza S, Van der Merwe A, Terrone C.   +12 more
europepmc   +6 more sources

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus [PDF]

Animal Models and Experimental Medicine
The global spread of mpox continues to pose a threat to public health, with immunocompromised patients being at greater risk for severe disease. This study aimed to establish a lethal severe infection model using NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mice,
Na Li, Ziqing Jia, Zhe Cong, Jianrong Ma, Jiahan Lu, Yongzhi Hou, Fei Wang, Jiasen Yang, Ting Chen, Jingjing Zhang, Dong Zhang, Jing Xue   +11 more
doaj   +2 more sources

Structural basis of DNA replication fidelity of the Mpox virus. [PDF]

Proc Natl Acad Sci U S A
The Mpox virus (MPXV) is an orthopoxvirus that caused a global outbreak in 2022. The poxvirus DNA polymerase complex is responsible for the replication and integrity of the viral genome; however, the molecular mechanisms underlying DNA replication fidelity are still unclear.
Xie Y, Kuai L, Peng Q, Wang Q, Wang H, Li X, Qi J, Ding Q, Shi Y, Gao GF.   +9 more
europepmc   +4 more sources