Results 21 to 30 of about 1,337,091 (204)

Rapid and sensitive one-tube detection of mpox virus using RPA-coupled CRISPR-Cas12 assay

Cell Reports: Methods, 2023
Summary: Mpox is caused by a zoonotic virus belonging to the Orthopoxvirus genus and the Poxviridae family. In this study, we develop a recombinase polymerase amplification (RPA)-coupled CRISPR-Cas12a detection assay for the mpox virus.
Fei Zhao, Yamei Hu, Zhangling Fan, Baoying Huang, Liang Wei, Yu Xie, Yu Huang, Shan Mei, Liming Wang, Lingwa Wang, Bin Ai, Jugao Fang, Chen Liang, Fengwen Xu, Wenjie Tan, Fei Guo   +15 more
doaj   +1 more source

Mpox Virus in Pregnancy, the Placenta, and Newborn

Archives of Pathology & Laboratory Medicine, 2023
Context.— Before its eradication, the smallpox virus was a significant cause of poor obstetric outcomes, including maternal and fetal morbidity and mortality. The mpox (monkeypox) virus is now the most pathogenic member of the Orthopoxvirus genus infecting humans.
Schwartz, D.A., Ha, S., Dashraath, P., Baud, D., Pittman, P.R., Adams Waldorf, K.M.   +5 more
openaire   +4 more sources

Development of a Novel Loop-Mediated Isothermal Amplification Method for the Rapid Detection of Monkeypox Virus Infections

Viruses, 2022
A recent outbreak of monkeypox virus (mpox) has prompted researchers to explore diagnostics as a means of impeding transmission and further spread. Rapid, sensitive, and specific methods are crucial for accurately diagnosing mpox infections.
Chao Yu, Lulu Zuo, Jing Miao, Lingjing Mao, Benjamin Selekon, Ella Gonofio, Emmanuel Nakoune, Nicolas Berthet, Gary Wong   +8 more
doaj   +1 more source

Molecular phylogenomic analysis reveals a single origin of monkeypox virus transmission in Guangzhou, China in June 2023

Biosafety and Health, 2023
The monkeypox (mpox) virus has caused worldwide transmission since its initial report in England in early May 2022. Available data from the World Health Organization (WHO) show that Europe and the Americas experienced a huge wave of mpox virus infection.
Mengling Jiang, Xizi Deng, Qinghong Fan, Fei Gu, Huiqin Yang, Jian Wang, Xiaoping Tang, Fengyu Hu, Yun Lan, Feng Li   +9 more
doaj   +1 more source

Urogenital Manifestations in Mpox (Monkeypox) Infection: A Comprehensive Review of Epidemiology, Pathogenesis, and Therapeutic Approaches [PDF]

Infection and Drug Resistance
Sike He,* Jinge Zhao,* Junru Chen, Jiayu Liang, Xu Hu, Xingming Zhang, Hao Zeng, Guangxi Sun Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China*These authors contributed ...
He S, Zhao J, Chen J, Liang J, Hu X, Zhang X, Zeng H, Sun G   +7 more
doaj   +1 more source

Identification of IMP Dehydrogenase as a Potential Target for Anti-Mpox Virus Agents

Microbiology Spectrum, 2023
Mpox virus (formerly monkeypox virus [MPXV]) is a neglected zoonotic pathogen that caused a worldwide outbreak in May 2022. Given the lack of an established therapy, the development of an anti-MPXV strategy is of vital importance.
Takayuki Hishiki, Takeshi Morita, Daisuke Akazawa, Hirofumi Ohashi, Eun-Sil Park, Michiyo Kataoka, Junki Mifune, Kaho Shionoya, Kana Tsuchimoto, Shinjiro Ojima, Aa Haeruman Azam, Shogo Nakajima, Madoka Kawahara, Tomoki Yoshikawa, Masayuki Shimojima, Kotaro Kiga, Ken Maeda, Tadaki Suzuki, Hideki Ebihara, Yoshimasa Takahashi, Koichi Watashi   +20 more
doaj   +1 more source

Wastewater analysis of Mpox virus in a city with low prevalence of Mpox disease: an environmental surveillance studyResearch in context

The Lancet Regional Health. Americas, 2023
Summary: Background: Tracking infectious diseases at the community level is challenging due to asymptomatic infections and the logistical complexities of mass surveillance. Wastewater surveillance has emerged as a valuable tool for monitoring infectious
Jeremiah Oghuan, Carlos Chavarria, Scout R. Vanderwal, Anna Gitter, Akpevwe Amanda Ojaruega, Carlos Monserrat, Cici X. Bauer, Eric L. Brown, Sara Javornik Cregeen, Jennifer Deegan, Blake M. Hanson, Michael Tisza, Hector I. Ocaranza, John Balliew, Anthony W. Maresso, Janelle Rios, Eric Boerwinkle, Kristina D. Mena, Fuqing Wu   +18 more
doaj   +1 more source

Rapid detection of mpox virus using recombinase aided amplification assay

Frontiers in Cellular and Infection Microbiology, 2023
A recent, unprecedented outbreak of human mpox virus infection has led to cases in non-African nations, and the number of confirmed or suspected cases outside of Africa has exceeded 1,000 within 5 weeks.
Xiaohu Cui, Bing Du, Bing Du, Junxia Feng, Yanling Feng, Jinghua Cui, Chao Yan, Hanqing Zhao, Lin Gan, Zheng Fan, Tongtong Fu, Ziying Xu, Rui Zhang, Shuheng Du, Yao Zhou, Ziyan Tian, Qun Zhang, Hanyu Fu, Guanhua Xue, Jing Yuan   +19 more
doaj   +1 more source

Emergence, phylogeography, and adaptive evolution of mpox virus

New Microbes and New Infections, 2023
Mpox (Monkeypox) is a zoonotic disease caused by mpox virus (MPXV). A multi-country MPXV outbreak in non-endemic demographics was identified in May 2022. A systematic evaluation of MPXV evolutionary trajectory and genetic diversity could be a timely addition to the MPXV diagnostics and prophylaxis.
Haifei Guan, Ijaz Gul, Chufan Xiao, Shuyue Ma, Yingshan Liang, Dongmei Yu, Ying Liu, Hong Liu, Can Yang Zhang, Juan Li, Peiwu Qin   +10 more
openaire   +3 more sources

Mpox vaccination basics [PDF]

Updated March 22, 2023Mpox (formerly known as monkeypox) is caused by a virus that is related to the virus that causes smallpox. JYNNEOS is a 2-dose vaccine developed to protect against mpox and smallpox infections.

core   +8 more sources