Results 31 to 40 of about 1,337,091 (204)

Design, evaluation, and immune simulation of potentially universal multi-epitope mpox vaccine candidate: focus on DNA vaccine

Frontiers in Microbiology, 2023
Monkeypox (mpox) is a zoonotic infectious disease caused by the mpox virus. Mpox symptoms are similar to smallpox with less severity and lower mortality.
Nino Rcheulishvili, Jiawei Mao, Dimitri Papukashvili, Shunping Feng, Cong Liu, Xingyun Wang, Yunjiao He, Peng George Wang   +7 more
doaj   +1 more source

Animal models of mpox virus infection and disease

Infectious Medicine, 2023
Mpox (monkeypox) virus (MPXV), which causes a mild smallpox-like disease, has been endemic in Africa for several decades, with sporadic cases occurring in other parts of the world. However, the most recent outbreak of mpox mainly among men that have sex with men has affected several continents, posing serious global public health concerns.
Zheng-Kai Wei, Yi-Cheng Zhao, Ze-Dong Wang, Li-Yan Sui, Ying-Hua Zhao, Quan Liu   +5 more
openaire   +3 more sources

Introduction of Mpox Virus Clade Ib into the Republic of the Congo. [PDF]

N Engl J Med
Koukouikila-Koussounda F, Yinda CK, Mayengue PI, Elenga RG, Boussam DAE, Indolo GD, Macosso LN, Munster VJ, Niama FR.   +8 more
europepmc   +3 more sources

Human mpox (monkeypox): Epidemiologic, pathogenetic and clinical characteristics, and prevention

One Health Bulletin, 2023
Mpox (monkeypox) is a zoonotic disease caused by monkeypox virus, which belongs to the orthopoxvirus genus. Concern has recently been expressed over the appearance of the human monkeypox virus and its severe clinical presentation that resembles smallpox.
Husheng Xiong, Jinlin Tan, Dingmei Zhang
doaj   +1 more source

Driving effect of multiplex factors on Mpox in global high-risk region, implication for Mpox based on one health concept

One Health, 2023
Mpox is an ongoing viral zoonotic disease epidemic worldwide. Being different from conventional animal-to-human transmission, the present outbreak is mainly caused by human-to-human transmission of Mpox virus, putting forward the risk of worldwide ...
Shan Gao, Zan Zeng, Yujia Zhai, Fangyuan Chen, Xiangning Feng, HongLong Xu, Wei Kan, Jiahai Lu, Jian Zhou, Zeliang Chen   +9 more
doaj   +1 more source

An improved and high-throughput mpox virus microneutralization assay. [PDF]

Biosaf Health
Since the 2022 global mpox outbreak, the lack of specific antibodies for mpox virus (MPXV) detection has hindered precise immunoassays due to cross-reactivity among Orthopoxviruses (OPXVs). This study developed and characterized two monoclonal antibodies (mAbs), CML01 and CML02, targeting the MPXV A35 protein, a conserved surface antigen of ...
Li D, Du Z, Zhang Q, Song R, Chen L, Huang H, Wang J, Guo L, Ren L.   +8 more
europepmc   +4 more sources

Prior viral infection determines the mode and severity of monkeypox virus

International Journal of Infectious Diseases, 2023
Objectives: Monkeypox (MPox) is a zoonotic virus in the genus Orthopoxvirus. It is transmitted from animal to human, and between humans. The clinical presentations vary, starting with a prodrome phase to different skin findings and systemic complications.
Hussain Hussain, Michael J. Paidas, Aya Fadel, Rajalakshmi Ramamoorthy, Efrain Garcia, Zahraa F. Saadoon, Ekaterina Casmartino, Luis Mendez, Erik A. Williams, Roberto Ruiz-Cordero, Arumugam R. Jayakumar   +10 more
doaj   +1 more source

Recapitulating productive infection of mpox virus in human skin organoids

, 2022
Bulk-RNA sequencing data of monkeypox (mpox) virus infection in human skin organoids. The dataset includes 1h and 7 days post-infection of mpox virus in human skin organoids, and treatment with antiviral drug TPOXX for 7 days post ...
Pan, PhD Q (Erasmus University Medical Center)
core   +1 more source

Urological Manifestation of Mpox Virus: A Scoping Review. [PDF]

Res Rep Urol
Mpox primarily presents with systemic and cutaneous symptoms. However, it can also lead to urological complications, necessitating specialized attention. The aim of this scoping review is to summarize the current evidence regarding the urological manifestations of Mpox, possible complications, and available treatments.An electronic systematic search of
Mantica G, Drocchi G, Chierigo F, Granelli G, Trani G, Paraboschi I, Alba S, Ambrosini F, De Klerk C, Riccardi N, Nozza S, Van der Merwe A, Terrone C.   +12 more
europepmc   +6 more sources

U.S. wastewater data : Mpox virus detection in wastewater in the past 4 weeks, United States

Updated September 6, 2023Mpox virus detection in wastewater in the past 4 weeks, United StatesCommunities can monitor the presence of mpox virus in wastewater samples.

core   +12 more sources