Results 11 to 20 of about 1,337,091 (204)

A comprehensive review of monkeypox virus and mpox characteristics [PDF]

Frontiers in Cellular and Infection Microbiology
Monkeypox virus (MPXV) is the etiological agent of monkeypox (mpox), a zoonotic disease. MPXV is endemic in the forested regions of West and Central Africa, but the virus has recently spread globally, causing outbreaks in multiple non-endemic countries ...
Emmanuel Alakunle, Daniel Kolawole, Diana Diaz-Cánova, Faith Alele, Oyelola Adegboye, Ugo Moens, Malachy Ifeanyi Okeke   +6 more
doaj   +5 more sources

Lymphofollicular lesions associated with monkeypox (Mpox) virus proctitis [PDF]

International Journal of Infectious Diseases, 2023
In the recent 2022 monkeypox (Mpox) global outbreak, cases have been mostly documented among men who have sex with men. Proctitis was reported in almost 14% of cases. In this study, four Mpox-confirmed cases requiring hospitalizations for severe proctitis were characterized by clinical, virological, microbiological, endoscopic, and histological aspects.
Mazzotta, Valentina, Scorzolini, Laura, Falasca, Laura, Lionetti, Raffaella, Aguglia, Camilla, Kontogiannis, Dimitra, Colombo, Daniele, Colavita, Francesca, De Palo, Maria Grazia, Carletti, Fabrizio, Mondi, Annalisa, Pinnetti, Carmela, Maffongelli, Gaetano, Garbuglia, Anna Rosa, Baldini, Francesco, Corpolongo, Angela, Maggi, Fabrizio, D'Offizi, Gianpiero, Girardi, Enrico, Vaia, Francesco, Nicastri, Emanuele, Del Nonno, Franca, Antinori, Andrea   +22 more
openaire   +4 more sources

MOSAIC: A cohort study of human mpox virus disease

Wellcome Open Research, 2023
Background Human mpox is a viral disease caused by an Orthopoxvirus, human mpox virus (hMPXV), typically causing fever and a rash. Mpox has historically been endemic to parts of Central and West Africa, with small numbers of imported cases reported elsewhere, but starting May 2022 an unprecedented global outbreak caused by clade IIb hMPXV was reported ...
Pesonel, E, Hoffmann, I, Guiraud, L, Bourner, J, Diallo, A, Dunning, J, Horby, P, Kali, S, Laouénan, C, Mentré, F, Merson, L, Molino, D, Palich, R, Rojek, A, Tacconelli, E, Tardivon, C, Yazdanpanah, Y, Calmy, A, Lescure, F-X, Olliaro, P   +19 more
openaire   +3 more sources

Evaluating the susceptibility of various common cell lines and assessing inactivation conditions to Mpox virus [PDF]

Microbiology Spectrum
Over the past decade, numerous infectious diseases have emerged. In 2022, the World Health Organization declared the Mpox outbreak a global public health emergency, as the virus spread rapidly to over 107 countries.
Shu-Chen Hsu, Ping-Cheng Liu, Shan-Ko Tsai, An-Yu Chen, Hui-Ping Tsai, Jun-Ren Sun, Ti-Yu Li, Pei-Yu Hsieh, Jyh-Yuan Yang, Tein-Yao Chang   +9 more
doaj   +2 more sources

Modeling the transmission dynamics of Mpox virus. [PDF]

Sci Rep
The global emergence of human monkeypox (Mpox) necessitates stage-structured transmission models. We develop a compartmental framework with Prodromal, Rash, and Complication stages, identifying critical thresholds through bifurcation analysis. A transcritical bifurcation at [Formula: see text] day[Formula: see text] separates stable disease-free ...
Rabiu S, Ali MKM.
europepmc   +4 more sources

Viroporins of Mpox Virus

International Journal of Molecular Sciences, 2023
Mpox or monkeypox virus (MPXV) belongs to the subclass of Poxviridae and has emerged recently as a global threat. With a limited number of anti-viral drugs available for this new virus species, it is challenging to thwart the illness it begets. Therefore, characterizing new drug targets in the virus may prove advantageous to curbing the disease.
Kingshuk Basu, Miriam Krugliak, Isaiah T. Arkin   +2 more
openaire   +2 more sources

Mpox infection investigation using multiplexed syndromic diagnostics: Evaluation of an AusDiagnostics multiplexed tandem PCR (MT-PCR) syndromic panel

Journal of Clinical Virology Plus, 2023
Background: Detection of mpox virus during investigation of viral vesicular rash illness is required to identify mpox infection. Objectives: This study evaluated the performance of a research-use-only (RUO) AusDiagnostics MT-PCR syndromic assay ...
M.J. Pond, J. Al-Mufti, P. Madona, M.A. Crone, K.G. Laing, R.S. Hale, D. Muir, P. Randell   +7 more
doaj   +1 more source

Pharmacological treatment and vaccines in monkeypox virus: a narrative review and bibliometric analysis

Frontiers in Pharmacology, 2023
Mpox (earlier known as monkeypox) virus infection is a recognized public health emergency. There has been little research on the treatment options. This article reviews the specific drugs used to treat mpox virus infection and the vaccines used here ...
Muhammad Aaqib Shamim, Prakisini Satapathy, Bijaya Kumar Padhi, Sai Dutt Veeramachaneni, Naushaba Akhtar, Anindita Pradhan, Abhimanyu Agrawal, Pradeep Dwivedi, Pradeep Dwivedi, Aroop Mohanty, Keerti Bhusan Pradhan, Russell Kabir, Ali A. Rabaan, Jawaher Alotaibi, Zainab A. Al Ismail, Zainab Ahmed Alsoliabi, Ali Al Fraij, Ranjit Sah, Ranjit Sah, Ranjit Sah, Alfonso J. Rodriguez-Morales, Alfonso J. Rodriguez-Morales   +21 more
doaj   +1 more source

Wastewater surveillance of Mpox virus in Baltimore

Science of The Total Environment, 2023
This study aimed to utilize wastewater surveillance for monitoring Mpox cases at a community level. Untreated wastewater samples were collected once a week from two wastewater treatment plants (A and B) in Baltimore City from July 27, 2022-September 22, 2022.
Sherchan, Samendra P., Solomon, Tamunobelema, Idris, Oladele, Nwaubani, Daniel, Thakali, Ocean   +4 more
openaire   +2 more sources

Pathogenicity and transmissibility of Mpox virus in African dormice. [PDF]

Microbiol Spectr
ABSTRACT The global spread of Mpox virus (MPXV) poses a major public health challenge, yet reliable and consistent animal models for MPXV evaluation remain limited, which hinders progress in developing treatment strategies and transmission-blocking technologies.
Chen Z, Zhang L, Li L, Shao M, Zhao Z, Shang C, Liu Z, Liu J, Liu Y, Li X, Guo Z.   +10 more
europepmc   +3 more sources