Results 11 to 20 of about 1,043,937 (210)

Mpox Virus in Pregnancy, the Placenta, and Newborn

Archives of Pathology & Laboratory Medicine, 2023
Context.— Before its eradication, the smallpox virus was a significant cause of poor obstetric outcomes, including maternal and fetal morbidity and mortality. The mpox (monkeypox) virus is now the most pathogenic member of the Orthopoxvirus genus infecting humans.
Schwartz, D.A., Ha, S., Dashraath, P., Baud, D., Pittman, P.R., Adams Waldorf, K.M.   +5 more
openaire   +4 more sources

Identification of mpox M1R and B6R monoclonal and bispecific antibodies that efficiently neutralize authentic mpox virus

Emerging Microbes and Infections
In 2022, the monkeypox virus (mpox virus, MPXV) exhibited global dissemination across six continents, representing a notable challenge owing to the scarcity of targeted antiviral interventions. Passive immunotherapy, such as the use of monoclonal antibodies (mAbs) and bispecific antibodies (bsAbs), has emerged as a promising option for antiviral ...
Chenguang Shen, Xiaohua Gong, Jiayin Chen   +2 more
exaly   +4 more sources

Introduction of Mpox Virus Clade Ib into the Republic of the Congo. [PDF]

N Engl J Med
Koukouikila-Koussounda F, Yinda CK, Mayengue PI, Elenga RG, Boussam DAE, Indolo GD, Macosso LN, Munster VJ, Niama FR.   +8 more
europepmc   +3 more sources

Viroporins of Mpox Virus

International Journal of Molecular Sciences, 2023
Mpox or monkeypox virus (MPXV) belongs to the subclass of Poxviridae and has emerged recently as a global threat. With a limited number of anti-viral drugs available for this new virus species, it is challenging to thwart the illness it begets. Therefore, characterizing new drug targets in the virus may prove advantageous to curbing the disease.
Kingshuk Basu, Miriam Krugliak, Isaiah T. Arkin   +2 more
openaire   +2 more sources

Mpox infection investigation using multiplexed syndromic diagnostics: Evaluation of an AusDiagnostics multiplexed tandem PCR (MT-PCR) syndromic panel

Journal of Clinical Virology Plus, 2023
Background: Detection of mpox virus during investigation of viral vesicular rash illness is required to identify mpox infection. Objectives: This study evaluated the performance of a research-use-only (RUO) AusDiagnostics MT-PCR syndromic assay ...
M.J. Pond, J. Al-Mufti, P. Madona, M.A. Crone, K.G. Laing, R.S. Hale, D. Muir, P. Randell   +7 more
doaj   +1 more source

Pharmacological treatment and vaccines in monkeypox virus: a narrative review and bibliometric analysis

Frontiers in Pharmacology, 2023
Mpox (earlier known as monkeypox) virus infection is a recognized public health emergency. There has been little research on the treatment options. This article reviews the specific drugs used to treat mpox virus infection and the vaccines used here ...
Muhammad Aaqib Shamim, Prakisini Satapathy, Bijaya Kumar Padhi, Sai Dutt Veeramachaneni, Naushaba Akhtar, Anindita Pradhan, Abhimanyu Agrawal, Pradeep Dwivedi, Pradeep Dwivedi, Aroop Mohanty, Keerti Bhusan Pradhan, Russell Kabir, Ali A. Rabaan, Jawaher Alotaibi, Zainab A. Al Ismail, Zainab Ahmed Alsoliabi, Ali Al Fraij, Ranjit Sah, Ranjit Sah, Ranjit Sah, Alfonso J. Rodriguez-Morales, Alfonso J. Rodriguez-Morales   +21 more
doaj   +1 more source

Wastewater surveillance of Mpox virus in Baltimore

Science of The Total Environment, 2023
This study aimed to utilize wastewater surveillance for monitoring Mpox cases at a community level. Untreated wastewater samples were collected once a week from two wastewater treatment plants (A and B) in Baltimore City from July 27, 2022-September 22, 2022.
Sherchan, Samendra P., Solomon, Tamunobelema, Idris, Oladele, Nwaubani, Daniel, Thakali, Ocean   +4 more
openaire   +2 more sources

Rapid and sensitive one-tube detection of mpox virus using RPA-coupled CRISPR-Cas12 assay

Cell Reports: Methods, 2023
Summary: Mpox is caused by a zoonotic virus belonging to the Orthopoxvirus genus and the Poxviridae family. In this study, we develop a recombinase polymerase amplification (RPA)-coupled CRISPR-Cas12a detection assay for the mpox virus.
Fei Zhao, Yamei Hu, Zhangling Fan, Baoying Huang, Liang Wei, Yu Xie, Yu Huang, Shan Mei, Liming Wang, Lingwa Wang, Bin Ai, Jugao Fang, Chen Liang, Fengwen Xu, Wenjie Tan, Fei Guo   +15 more
doaj   +1 more source

Development of a Novel Loop-Mediated Isothermal Amplification Method for the Rapid Detection of Monkeypox Virus Infections

Viruses, 2022
A recent outbreak of monkeypox virus (mpox) has prompted researchers to explore diagnostics as a means of impeding transmission and further spread. Rapid, sensitive, and specific methods are crucial for accurately diagnosing mpox infections.
Chao Yu, Lulu Zuo, Jing Miao, Lingjing Mao, Benjamin Selekon, Ella Gonofio, Emmanuel Nakoune, Nicolas Berthet, Gary Wong   +8 more
doaj   +1 more source

Molecular phylogenomic analysis reveals a single origin of monkeypox virus transmission in Guangzhou, China in June 2023

Biosafety and Health, 2023
The monkeypox (mpox) virus has caused worldwide transmission since its initial report in England in early May 2022. Available data from the World Health Organization (WHO) show that Europe and the Americas experienced a huge wave of mpox virus infection.
Mengling Jiang, Xizi Deng, Qinghong Fan, Fei Gu, Huiqin Yang, Jian Wang, Xiaoping Tang, Fengyu Hu, Yun Lan, Feng Li   +9 more
doaj   +1 more source