Results 91 to 100 of about 5,325 (169)

Clade IIb Mpox virus (MPXV) vertical transmission and fetal demise in a pregnant rhesus macaque model.

Infection with clade I Mpox virus (MPXV) results in adverse pregnancy outcomes, yet the potential for vertical transmission resulting in fetal harm with clade IIb MPXV, the clade that is currently circulating in the Western Hemisphere, remains unknown ...
Terry Morgan, Saverio V Capuano, Amy Kamholz, Ann M Mitzey, Amy Moy, Puja Basu, Xiankun Zeng, Julie A Karl, Elaina R Razo, Heather A Simmons, David H O'Connor, Thomas C Friedrich, Saswati Bhattacharya, Thaddeus G Golos, Emma L Mohr, Andrea M Weiler, Grace VanSleet, Nicholas P Krabbe, Nell Bekiares, Gregory Daggett   +19 more
core   +1 more source

Development of a multiplex real-time PCR for the simultaneous detection of monkeypox virus clades I, II, and goatpox virus

Frontiers in Veterinary Science
IntroductionMonkeypox virus (MPXV) hosts are of multiple species, with a risk of cross-species transmission. This phenomenon poses a threat to unreported affected domestic animals and increases the risk to human public health.
Yongqiang Lin, Zijing Guo, Jinsong Chen, Xianwen Zhang, Long Zhou, Yanmin Li, Zhidong Zhang   +6 more
doaj   +1 more source

Compromised NK cell functions upon MPXV infection.

, 2013
Frequency of the expression of CD107a, IFN-γ, and TNF-α by different NK cell subsets from day 8-9 blood and LN samples is shown. Calculation of mean frequency of expression from control (dotted line) and MPXV-infected NHPs (solid line) was performed with
Laura Bollinger (473336), Catherine Jett (399621), Melanie Cohen (473334), Nicole Josleyn (399620), R. Keith Reeves (140179), Reed Johnson (473335), Peter B. Jahrling (202169), Haifeng Song (22439), Krisztina Janosko (399618), Gerald Jennings (399625), Joseph E. Blaney (211328), Jeff Skinner (473333)   +11 more
core   +1 more source

Weight-change in MPXV challenged mice.

, 2015
Vaccinated and control mice were challenged with 2x105 PFU of MPXV 50 days following the initial vaccination with MVA or BoHV-4 vectors A29L (A), M1R (B), B6R (C), or a combination of all 3 vectors (D). Mice were monitored for weight-change.
Mark R. Buller (757254), Valentina Franceschi (155274), Daniela Pompilio (757251), Scott Parker (189670), Ryan W. Crump (757248), Edguardo Hembrador (757250), Gaetano Donofrio (81313), Sarah Jacca (587593), Ryan D. Estep (757253), Scott W. Wong (359277), Giulia Tebaldi (757252), Konstantin Doronin (757249)   +11 more
core   +1 more source

Antibodies Induced by Smallpox Vaccination after at Least 45 Years Cross-React with and In Vitro Neutralize Mpox Virus: A Role for Polyclonal B Cell Activation?

Viruses
Aims: To evaluate whether antibodies specific for the vaccinia virus (VV) are still detectable after at least 45 years from immunization. To confirm that VV-specific antibodies are endowed with the capacity to neutralize Mpox virus (MPXV) in vitro.
Sabrina Mariotti, Giulietta Venturi, Maria Vincenza Chiantore, Raffaela Teloni, Riccardo De Santis, Antonello Amendola, Claudia Fortuna, Giulia Marsili, Giorgia Grilli, Maria Stella Lia, Seble Tekle Kiros, Filippo Lagi, Alessandro Bartoloni, Angelo Iacobino, Raffaele Cresta, Marco Lastilla, Roberto Biselli, Paola Di Bonito, Florigio Lista, Roberto Nisini   +19 more
doaj   +1 more source

Durable but impaired humoral and cellular immune responses against monkeypox virus in people with HIV over 18 months

Journal of Translational Medicine
Background Monkeypox virus (MPXV), a zoonotic orthopoxvirus (OPXV), re-emerged as a global public health concern following the 2022 multi-country outbreak that disproportionately affected people with human immunodeficiency virus (HIV).
Lulu Xing, Xinyue Wang, Meiqing Jiang, Huiwen Yan, Xingyun Zhao, Jing Liu, Jiang Xiao, Ying Liu, Chuan Song, Qiyao Pu, Ronghua Jin, Xi Wang, Hongxin Zhao, Yaxian Kong   +13 more
doaj   +1 more source

Differentiating mpox infection and vaccination using a validated multiplex orthopoxvirus IgG serology assay

Journal of Clinical Microbiology
The resurgence of monkeypox virus (MPXV) has increased demand for validated serological assays to assess exposure and immunity. Cross-reactivity among orthopoxviruses, stemming from high sequence conservation, complicates distinguishing antibody ...
Jonathan C. Reed, Cecilia Downs, Kaden McAllister, Clarice Mauer, Christopher L. McClurkan, Donna Wilson, Kate Holzhauer, Jane A. Dickerson, Chase A. Cannon, Tara M. Babu, Matthew R. Golden, David M. Koelle, Alexander L. Greninger   +12 more
doaj   +1 more source

Contents

Journal of the International AIDS Society, Volume 29, Issue S2, July 2026.
wiley   +1 more source

Investigação Molecular para a Presença de Monkeypoxvirus (MPXV) em um Macaco Bebê

, 2023
Background: Monkeypox is a zoonotic virus that transmits from animal to human and human to human. Despite the fact that the Monkeypox virus (MPXV) was initially isolated in 1958 and the first human case was reported in 1970, thousands of cases have been ...
Kale, Mehmet, Koçlu, Ozan, Usta, Ayşegül, Yıldırım, Yakup, Özmen, Özlem, Orta, Yakup Sinan   +5 more
core  

Differential replication, pathology, and immune response of clade IIb mpox virus in C57BL/6 and BALB/c mice

Emerging Microbes and Infections
We have previously established a clade IIb mpox virus (MPXV) pathogenic BALB/c mouse model for developing mpox countermeasures. Here, we comprehensively investigated the susceptibility of BALB/c and C57BL/6 mice to MPXV and found that Clade IIb MPXV was ...
Meimei Duan, Xiangmei Zhang, Xian Tang, Zhuohuan Li, Wenqi Huang, Qi Chen, Mingxia Zhang, Lin Cheng, Zheng Zhang   +8 more
doaj   +1 more source