Results 91 to 100 of about 4,135 (173)

Durable but impaired humoral and cellular immune responses against monkeypox virus in people with HIV over 18 months

Journal of Translational Medicine
Background Monkeypox virus (MPXV), a zoonotic orthopoxvirus (OPXV), re-emerged as a global public health concern following the 2022 multi-country outbreak that disproportionately affected people with human immunodeficiency virus (HIV).
Lulu Xing, Xinyue Wang, Meiqing Jiang, Huiwen Yan, Xingyun Zhao, Jing Liu, Jiang Xiao, Ying Liu, Chuan Song, Qiyao Pu, Ronghua Jin, Xi Wang, Hongxin Zhao, Yaxian Kong   +13 more
doaj   +1 more source

Development of a multiplex real-time PCR for the simultaneous detection of monkeypox virus clades I, II, and goatpox virus

Frontiers in Veterinary Science
IntroductionMonkeypox virus (MPXV) hosts are of multiple species, with a risk of cross-species transmission. This phenomenon poses a threat to unreported affected domestic animals and increases the risk to human public health.
Yongqiang Lin, Zijing Guo, Jinsong Chen, Xianwen Zhang, Long Zhou, Yanmin Li, Zhidong Zhang   +6 more
doaj   +1 more source

Development and clinical evaluation of a MPXV antigen-detecting rapid diagnostic test

Journal of Virological Methods
To address the global emergence of mpox after the 2022 epidemic, a rapid and accurate diagnostic tool is needed at the point of care to identify individuals infected with mpox virus (MPXV) to prevent and control the spread of the virus. We designed an antigen-detecting rapid diagnostic test that exclusively detects MPXV without cross-reacting with the ...
Nobuyuki Kurosawa, Tatsuhiko Ozawa, Kousei Ozawa, Masayuki Shimojima, Madoka Kawahara, Fumi Kasuya, Wakaba Okada, Mami Nagashima, Kenji Sadamasu, Masae Itamochi, Hideki Tani, Yoshitomo Morinaga, Kosuke Yuhara, Jun Okamoto, Haruna Ichikawa, Takashi Kawahata, Tomomi Yamazaki, Masaharu Isobe   +17 more
openaire   +2 more sources

Differentiating mpox infection and vaccination using a validated multiplex orthopoxvirus IgG serology assay

Journal of Clinical Microbiology
The resurgence of monkeypox virus (MPXV) has increased demand for validated serological assays to assess exposure and immunity. Cross-reactivity among orthopoxviruses, stemming from high sequence conservation, complicates distinguishing antibody ...
Jonathan C. Reed, Cecilia Downs, Kaden McAllister, Clarice Mauer, Christopher L. McClurkan, Donna Wilson, Kate Holzhauer, Jane A. Dickerson, Chase A. Cannon, Tara M. Babu, Matthew R. Golden, David M. Koelle, Alexander L. Greninger   +12 more
doaj   +1 more source

Transmission of MPXV from fire-footed rope squirrels to sooty mangabeys

Nature
Abstract Mpox, caused by the monkeypox virus (MPXV; Orthopoxvirus monkeypox ), is on the rise in West and Central Africa 1–3 . African rodents, especially squirrels, are suspected to be involved in MPXV emergence, but no evidence of a ...
Riutord-Fe, Carme, Schlotterbeck, Jasmin, Lagostina, Lorenzo, Kouadio, Leonce, Herridge, Harriet, Jochum, Moritz, Noma, Nea Yves, López-Morales, Ane, Hoffmann, Donata, Calvelage, Sten, Kühl, Hjalmar, Mielke, Alexander, Crockford, Catherine, Samuni, Liran, Wittig, Roman, Beer, Martin, Gonedelé-Bi, Sery, Gogarten, Jan, Calvignac-Spencer, Sébastien, Düx, Ariane, Patrono, Livia, Leendertz, Fabian   +21 more
openaire   +4 more sources

Monkeypox virus and type 1 diabetes: a molecular insight into inflammatory signaling and β-cell autoimmunity

Virology Journal
The current worldwide pandemic of monkeypox (MPXV) elicited apprehensions over its possible long-term health ramifications. Recent data indicate a potential association between MPXV infection and the onset of autoimmune disorders, such as type 1 diabetes
Yahya A. Almutawif, Haydar M. Al-kuraishy, Ali I. Al-Gareeb, Ali K. Albuhadily, Hamza M. A. Eid, Athanasios Alexiou, Marios Papadakis, Mohammed E. Abo‑El Fetoh, Gaber El-Saber Batiha   +8 more
doaj   +1 more source

Differential replication, pathology, and immune response of clade IIb mpox virus in C57BL/6 and BALB/c mice

Emerging Microbes and Infections
We have previously established a clade IIb mpox virus (MPXV) pathogenic BALB/c mouse model for developing mpox countermeasures. Here, we comprehensively investigated the susceptibility of BALB/c and C57BL/6 mice to MPXV and found that Clade IIb MPXV was ...
Meimei Duan, Xiangmei Zhang, Xian Tang, Zhuohuan Li, Wenqi Huang, Qi Chen, Mingxia Zhang, Lin Cheng, Zheng Zhang   +8 more
doaj   +1 more source

Contents

Journal of the International AIDS Society, Volume 29, Issue S2, July 2026.
wiley   +1 more source

Ulcerative Pathogens Among Suspected Monkeypox Virus (MPXV) Patients: A Cross Sectional Study

Actas Dermo-Sifiliográficas
MPXV suspected lesions were tested to other ulcerative pathogens in order to detect coinfections and establish an adequate diagnosis. Descriptive retrospective cross-sectional study taken at Centro Sanitario Sandoval, Madrid.
J.A. Pérez-García, A. Pujol, E. Orviz, M. Vera, O. Ayerdi, T. Puerta, N. Fernández, V. Estrada, J. Del Romero, A. Delgado-Iribarren   +9 more
doaj   +1 more source

MPXV Sequencing from Wastewater (ONT) V1.0 v1

This protocol is designed to sequence MPXV from wastewater samples using a limited amplicon scheme that targets all MPXV clades, subclades, and lineages.
Allison Steedman, Mark Zeller
openaire   +1 more source