Results 21 to 30 of about 5,325 (169)

Monkeypox virus: Future role in Human population

Journal of Infection and Public Health, 2022
Background: Monkeypox viral infection is considered as global public health and a rare disease caused by Monkeypox virus (MPXV), which is caused by smallpox-like virus and it causes pustules all over the body.
Abdullah Farasani
doaj   +1 more source

Virtual Screening of Bacteriocins From Lactic Acid Bacteria Against Monkeypox DNA Polymerase: Sakacin P and Mundticin KS Emerge as Promising Candidates. [PDF]

Food Sci Nutr
This study employs an in silico virtual screening workflow to evaluate lactic acid bacteria (LAB)‐derived bacteriocins as potential inhibitors of the monkeypox virus DNA polymerase (MPDP). Protein‐peptide docking simulations using the HADDOCK platform revealed that Sakacin P and Mundticin KS possess the highest binding affinities for the MPDP target ...
Karaman MZ, Goel K, Zanchi FB, Ozdarendeli A, Mujwar S, Yetiman AE, Fidan O.   +6 more
europepmc   +2 more sources

An In Silico Analysis of PCR-Based Monkeypox Virus Detection Assays: A Case Study for Ongoing Clinical Surveillance

Viruses, 2023
The 2022 global Mpox outbreak swiftly introduced unforeseen diversity in the monkeypox virus (MPXV) population, resulting in numerous Clade IIb sublineages.
Kuncheng Song, Hayden N. Brochu, Qimin Zhang, Jonathan D. Williams, Lakshmanan K. Iyer   +4 more
doaj   +1 more source

Clinical case of cavernitis — complicated monkeypox infection

Инфекция и иммунитет
The article presents a clinical case of monkeypox (MPOX) infection, a rare acute viral zoonosis until 2022, previously endemic in Africa, but currently recorded worldwide, including Europe and Bulgaria.
E. D. Lyutsova, I. G. Radeva, K. N. Nikolova, K. B. Karaivanov, D. M. Radkova, M. D. Gospodinova   +5 more
doaj   +1 more source

Monkeypox Virus (MPXV) Transmission Dynamics in Neighboring Countries as a Potential Threat to Kazakhstan. [PDF]

Viruses
The global outbreak of monkeypox virus (MPXV) demonstrated qualitatively new epidemiological characteristics of the infection, significantly different from previous outbreaks, mainly limited to the regions of Central and West Africa.
Kutumbetov L, Myrzakhmetova B, Chervyakova O, Zhugunissov K, Myngbay A, Temirzhanova A, Issimov A, Admanova G, Bakytzhanova M, Almat S, Issengaliyeva G, Shakhmanova A.   +11 more
europepmc   +2 more sources

One-step growth curves for parental (MPXV-Congo, MPXV-USA-2003) and progeny recombinant (MPXV-Congo-Luc+, MPXV-USA-Luc+) viruses.

, 2013
Vero cell monolayers were infected at multiplicity of infection (MOI) of 0.1 with parental (MPXV-Congo, MPXV-USA-2003) or with progeny (MPXV-Congo-Luc+, MPXV-USA-Luc+) strains.
Jorge E. Osorio (211899), Carol U. Meteyer (157786), Keith P. Iams (371232), Tonie E. Rocke (351855)   +3 more
core   +1 more source

MPXV qPCR amplification standard curve.

, 2014
MPXV qPCR amplification standard curve.
Edmond K. Magazani (566118), Jean-Luc Gala (396991), Leonid M. Irenge (566117), Jean-Jacques T. Muyembe (566119), Catherine Dumont (566116), Mostafa Bentahir (520437), Daniel Garin (375216)   +6 more
core   +1 more source

Current and Perspective Sensing Methods for Monkeypox Virus

Bioengineering, 2022
The outbreak of the monkeypox virus (MPXV) in non-endemic countries is an emerging global health threat and may have an economic impact if proactive actions are not taken.
Ijaz Gul, Changyue Liu, Xi Yuan, Zhicheng Du, Shiyao Zhai, Zhengyang Lei, Qun Chen, Muhammad Akmal Raheem, Qian He, Qiuyue Hu, Chufan Xiao, Zhang Haihui, Runming Wang, Sanyang Han, Ke Du, Dongmei Yu, Can Yang Zhang, Peiwu Qin   +17 more
doaj   +1 more source

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source