Results 41 to 50 of about 27,650 (231)

Developing Highly Effective Nanoparticle mRNA Therapeutic for Pediatric Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng, Wen Gao, Jonathan Do, Danli Lu, Ying‐Wei Lan, Andreas Damianos, Gautam Verma, Ali Al Siraj, Isabella Lowry, Lance Peter, Nicholas E. Banovich, Fei Sun, Hua He, Tanya V. Kalin, Vladimir V. Kalinichenko   +14 more
wiley   +1 more source

Multiscale Regulation of Ru‐Based Catalysts for Upgrading Biomass‐Derived Levulinic Acid and Levulinates to γ‐Valerolactone: Mechanisms, Advances, and Challenges

Advanced Science, EarlyView.
This review summarizes recent advances in the mechanistic, thermodynamic, and kinetic studies of biomass‐derived levulinic acid/levulinates conversion to γ‐valerolactone, along with the corresponding multiscale regulation strategies of Ru‐based catalysts.
Xin Ni, Cailu Xiao, Gongbing Zhou, Jingzi Zhang   +3 more
wiley   +1 more source

Mean Platelet Volume Has Prognostic Value in Chronic Lymphocytic Leukemia

Cancer Management and Research, 2020
Marta Masternak,1 Bartosz Puła,2 Joanna Knap,1 Anna Waszczuk-Gajda,3 Joanna Drozd-Sokołowska,3 Kamil Wdowiak,4 Sebastian Grosicki,5 Izabela Kozłowska,6 Marta Kaźmierczak,6 Anna Łabędź,7 Łukasz Szukalski,8 Kamil Wiśniewski,2 Edyta Subocz,9 Janusz Hałka,10
Masternak M, Puła B, Knap J, Waszczuk-Gajda A, Drozd-Sokołowska J, Wdowiak K, Grosicki S, Kozłowska I, Kaźmierczak M, Łabędź A, Szukalski Ł, Wiśniewski K, Subocz E, Hałka J, Szymczyk A, Hus M, Jamroziak K, Giannopoulos K   +17 more
doaj  

Masked polycythemia Vera (mPV): Results of an international study [PDF]

American Journal of Hematology, 2013
We examined the baseline features and clinical outcomes of 140 patients presenting with JAK2V617F positivity and a bone marrow morphology conforming with WHO criteria of polycythemia vera (PV), but a hemoglobin level of <18.5 g/dL in males (range 16.0–18.4) and <16.5 g/dL in females (range 15.0–16.4).
Barbui T, Thiele J, Gisslinger H, Finazzi G, Carobbio A, Rumi E, Luigia Randi M, Betozzi I, VANNUCCHI, ALESSANDRO MARIA, PIERI, LISA, Carrai V, Gisslinger B, Müllauer L, Ruggeri M, Rambaldi A, Tefferi A.   +15 more
openaire   +5 more sources

Success of coastal sage scrub restoration is influenced by local adaptations of shrub species

American Journal of Botany, EarlyView.
Abstract Premise Restoring plant communities is increasingly challenging with climate change. While practitioners have traditionally used local seed sources, many are recommending assisted migration, possibly from more extreme environments such as inland rather than coastal environments, for restoration.
Moises R. Perea‐Vega, Megan E. Lulow, Julie E. Coffey, Amy K. Henry, Katharina T. Schmidt, Priscilla M. Ta, Kailen A. Mooney, Sarah Kimball   +7 more
wiley   +1 more source

EVALUATION OF RDW, MPV, PLATELET LABORATORY PARAMETERS IN PROSTATE CANCER PATIENTS ADMITTING TO EMERGENCY DEPARTMENT WITH HEMATURIA

International Journal of Health Services Research and Policy, 2020
Prostate Cancer (PCA) is the most common among urological malignant tumors. Prostate cancer patients may be unable to urinate, and may have hospital admissions with symptoms like erectile dysfunction or hematuria.
Dilek Atik
doaj   +1 more source

A hospital based cross-sectional study on platelet parameters in adult patients with dengue, its serological subgroups, and controls

Platelets, 2022
Our objective was to analyze if there was a significant relationship between platelet parameters (PLT, MPV, PDW, P-LCR, PCT) among dengue, its serological subgroups and controls.
Antony Gnana Shahila M, Prabhavati Jothilingam   +1 more
doaj   +1 more source

Predictability of depression by plasma low-grade inflammatory markers in the background of Pediatric Celiac disease

Klinik Psikiyatri Dergisi, 2023
INTRODUCTION: Previous hypothesis on the predictability of either psychopathological or chronic metabolic disorders by complete blood count (CBC)-derived, low-grade peripheral inflammatory indicators should be considered with caution given the ...
Ayşegül Efe, Ayşegül Tok
doaj   +1 more source

Baihe Zhimu Decoction ameliorates anxious depression via PI3K/AKT/mTOR pathway‐mediated neuroprotection and inhibition of hippocampal neuronal apoptosis

Animal Models and Experimental Medicine, EarlyView.
Baihe Zhimu Decoction alleviates anxious depression‐like behaviors and protects hippocampal neurons. Chemical profiling and network pharmacology reveal multiple active components acting via the PI3K/AKT/mTOR pathway, enhancing neuronal survival and function, as confirmed by multi‐level in vitro and in vivo validation.
Yuanshan Han, Kexin He, Haolan Yang, Jiacheng Dai, Ronglin Chen, Yang Liu, Yuhong Wang, Lin Tang, Hongqing Zhao   +8 more
wiley   +1 more source

Origin, evolution and biogeographic dynamics of the European rabbit (Oryctolagus cuniculus) in Southwestern Europe

The Anatomical Record, EarlyView.
Abstract The Pleistocene is a key period for understanding the evolutionary history and palaeobiogeography of the European rabbit (Oryctolagus cuniculus). The species was first documented in southeastern Iberia at the beginning of the Middle Pleistocene and appears to have rapidly spread throughout Southwestern Europe, where it was found in numerous ...
Maxime Pelletier
wiley   +1 more source