Results 41 to 50 of about 1,669,562 (240)

A randomized phase II trial of MR-guided prostate stereotactic body radiotherapy administered in 5 or 2 fractions for localized prostate cancer (FORT)

BMC Cancer, 2023
Background Ultra-hypofractionated regimens for definitive prostate cancer (PCa) radiotherapy are increasingly utilized due in part to promising safety and efficacy data complemented by greater patient convenience from a treatment course requiring fewer ...
Sydney Wolfe, Marshall A. Diven, Ariel E. Marciscano, Xi Kathy Zhou, A. U. Kishan, M. L. Steinberg, Joseph A. Miccio, Philip Camilleri, Himanshu Nagar   +8 more
doaj   +1 more source

Modelling and reconstructing the respiratory motion of the liver [PDF]

, 2013
Respiratory organ motion is a complicating factor in tumour treatment. For dose delivery, the aim is to obtain a possibly static target in the beam's eye view whenever the beam is on.
Preiswerk, Frank
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Clinical outcomes and quality of life in glioblastoma patients treated with MR-guided adaptive radiotherapy using a 1.5 T MR-Linac in an Australian setting

Clinical and Translational Radiation Oncology
Purpose: The magnetic resonance linear accelerator (MRL) enables daily adaptation of radiation therapy plans. This study presents our institutional experience with the clinical outcomes and quality of life (QoL) of glioblastoma patients treated using a 1.
Kurl Jamora, Morikatsu Wada, Richard Khor, Hui Gan, Augusto Gonzalvo, Lawrence Cher, Eddie Lau, Mark Tacey, Georgia Barjaktarovic, Sandra Fisher, Felicity Height, Farshad Foroudi, Andrew M Scott, Sweet Ping Ng   +13 more
doaj   +1 more source

2023 Menoufia University Oncology Conference Invited Presentation: "MR-GUIDED ADAPTIVE HEAD AND NECK RADIOTHERAPY"

, 2023
Presentation by Dr. Fuller on 2023-09-07 for the Menoufia University Oncology Conference. Précis: "The MR-guided radiotherapy provides potential avenues to improve adaptive replanning for head and neck cancers in manners unfeasible with CT-based ...
Clifton Fuller (528030)
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights From a Large International Sicca Registry

Arthritis Care &Research, EarlyView.
Objective The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögren's International Collaborative Clinical Alliance (SICCA) cohort. Methods We performed a retrospective analysis examining 16 ocular symptoms (most graded 0–4) and artificial tear (AT) use (graded 0–3) as predictors of DED signs (abnormal ocular ...
Pragnya R. Donthineni, Chloe Shields, Rohit Muralidhar, Shreya Bhatt, Alan Baer, Robert Fox, Sara S. McCoy, Anat Galor   +7 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

A body mass index-based method for “MR-only” abdominal MR-guided adaptive radiotherapy

Zeitschrift für Medizinische Physik
Purpose: Dose calculation for MR-guided radiotherapy (MRgRT) at the 0.35 T MR-Linac is currently based on deformation of planning CTs (defCT) acquired for each patient.
Carolin Rippke, C. Katharina Renkamp, Christiane Stahl-Arnsberger, Annette Miltner, Carolin Buchele, Juliane Hörner-Rieber, Jonas Ristau, Jürgen Debus, Markus Alber, Sebastian Klüter   +9 more
doaj   +1 more source