Results 71 to 80 of about 801,823 (212)

Enhanced MRI-guided radiotherapy with gadolinium-based nanoparticles: preclinical evaluation with an MRI-linac

Cancer Nanotechnology, 2020
Background The AGuIX® (NH TherAguix) nanoparticle has been developed to enhance radiotherapy treatment and provide strong MR contrast. These two properties have previously been investigated separately and progressed to clinical trial following a clinical
H. L. Byrne, G. Le Duc, F. Lux, O. Tillement, N. M. Holmes, A. James, U. Jelen, B. Dong, G. Liney, T. L. Roberts, Z. Kuncic   +10 more
doaj   +1 more source

How bone mis‐segmentation affects MRI‐based sCT dosimetry in head and neck radiotherapy: A CT‐referenced study

Journal of Applied Clinical Medical Physics, Volume 27, Issue 9, September 2026.
Abstract Background Magnetic resonance imaging (MRI) is commonly used for head‐and‐neck (H&N) delineation in radiotherapy (RT) owing to the lack of contrast in computed tomography (CT) images. MRI‐based dosimetry is not yet fully developed for the H&N area due to the inter‐patient variability and the difficulty of accurately quantifying cortical bone ...
Laura Sayaque, Nils Tanneau, Charlène Bouyer, Benjamin Leporq, Oliver Hamelin, Frank Pilleul, Vincent Gregoire, Olivier Beuf   +7 more
wiley   +1 more source

Quantifying uncertainties associated with reference dosimetry in an MR‐Linac

Journal of Applied Clinical Medical Physics, 2023
AbstractBackgroundMagnetic resonance (MR)‐guided radiation therapy provides capabilities to utilize high‐resolution and real‐time MR imaging before and during treatment, which is critical for adaptive radiotherapy. This emerging modality has been promptly adopted in the clinic settings in advance of adaptations to reference dosimetry formalism that are
Iakovenko, Viktor, Keller, Brian, Malkov, Victor N., Sahgal, Arjun, Sarfehnia, Arman   +4 more
openaire   +2 more sources

Application of Continuous Positive Airway Pressure for Thoracic Respiratory Motion Management: An Assessment in a Magnetic Resonance Imaging–Guided Radiation Therapy Environment

Advances in Radiation Oncology, 2022
Purpose: Patient tolerability of magnetic resonance (MR)–guided radiation treatment delivery is limited by the need for repeated deep inspiratory breath holds (DIBHs).
Evan Liang, MD, Jennifer L. Dolan, PhD, Eric D. Morris, PhD, Jonathan Vono, RRT, Luisa F. Bazan, MD, Mei Lu, PhD, Carri K. Glide-Hurst, PhD   +6 more
doaj   +1 more source

Failure modes and effects analysis for clinical implementation of online adaptive radiotherapy: A systematic review

Journal of Applied Clinical Medical Physics, Volume 27, Issue 9, September 2026.
Abstract Background The accuracy of radiotherapy is limited by anatomical variations occurring over time scales ranging from sub‐seconds to days. Online Adaptive Radiotherapy (OART) addresses this by enabling daily plan adaptation based on real‐time imaging.
Deepikaa Balaji, Sonja Wegener, Sebastian Klüter, Sara L. Hackett   +3 more
wiley   +1 more source

3D gel dosimeter assessment for end-to-end geometric accuracy determination of the online adaptive workflow on the 1.5 T MR-linac

Physics and Imaging in Radiation Oncology
Background and purpose:: During an end-to-end (E2E) test on the online workflow of the MR-linac, the performance of the treatment starting from the acquisition of pre-treatment MRI scans and ending with dose delivery is quantified.
Stijn Oolbekkink, Jochem W.H. Wolthaus, Bram van Asselen, Bas W. Raaymakers   +3 more
doaj   +1 more source

A randomized phase II trial of MR-guided prostate stereotactic body radiotherapy administered in 5 or 2 fractions for localized prostate cancer (FORT)

BMC Cancer, 2023
Background Ultra-hypofractionated regimens for definitive prostate cancer (PCa) radiotherapy are increasingly utilized due in part to promising safety and efficacy data complemented by greater patient convenience from a treatment course requiring fewer ...
Sydney Wolfe, Marshall A. Diven, Ariel E. Marciscano, Xi Kathy Zhou, A. U. Kishan, M. L. Steinberg, Joseph A. Miccio, Philip Camilleri, Himanshu Nagar   +8 more
doaj   +1 more source

Evaluation of AI‐based segmentation and synthetic CT generation for MRI‐only prostate radiotherapy planning

Journal of Applied Clinical Medical Physics, Volume 27, Issue 9, September 2026.
Abstract Background There is an increasing use of magnetic resonance imaging (MRI) for segmentation of target volumes and organs at risk due to superior soft tissue contrast compared to computed tomography (CT). Conventional workflows require CT‐MRI registration, introducing geometric uncertainty that can propagate to dose delivery.
Amanda Östensson, Joakim Jonsson
wiley   +1 more source

Evaluation of the environ SRS immobilization mask system for HyperArc: Dosimetric attenuation, dose calculation accuracy, and clinical setup reproducibility

Journal of Applied Clinical Medical Physics, Volume 27, Issue 9, September 2026.
Abstract Background Frameless thermoplastic masks are standard for intracranial stereotactic radiosurgery (SRS), with the Encompass (CQ Medical) widely used on the Varian HyperArc platform. A candidate mask must minimize beam attenuation, permit accurate dose calculation, and enable reproducible setup, yet these are rarely assessed together ...
Adi Robinson, Matthew R. Caldwell
wiley   +1 more source

Start to end simulations of the ERL prototype at Daresbury Laboratory [PDF]

, 2005
Daresbury Laboratory is currently building an Energy Recovery Linac Prototype (ERLP) that will serve as a research and development facility for the study of beam dynamics and accelerator technology important to the design and construction of the proposed
Bowler, M, Gerth, C, Muratori, B, McNeil, B W J, Faatz, B, Owen, H L   +5 more
core   +1 more source