Results 51 to 60 of about 801,823 (212)

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

Three dimensional simulation and magnetic decoupling of the linac in a linac-MR system [PDF]

, 2010
Real time image guided radiotherapy has been proposed by integrating an in-line 6 MV linear accelerator (linac) to a magnetic resonance (MR) imager in either a parallel or transverse configuration.
St. Aubin, Joel
core   +1 more source

4D-MRI driven MR-guided online adaptive radiotherapy for abdominal stereotactic body radiation therapy on a high field MR-Linac: Implementation and initial clinical experience

Clinical and Translational Radiation Oncology, 2020
Background and purpose: In this report, we describe our implementation and initial clinical experience using 4D-MRI driven MR-guided online adaptive radiotherapy (MRgOART) for abdominal stereotactic body radiotherapy (SBRT) on the Elekta Unity MR-Linac ...
Eric S. Paulson, Ergun Ahunbay, Xinfeng Chen, Nikolai J. Mickevicius, Guang-Pei Chen, Christopher Schultz, Beth Erickson, Michael Straza, William A. Hall, X. Allen Li   +9 more
doaj   +1 more source

Comparison of Intensity Modulated Radiotherapy Treatment Plans Between 1.5T MR-Linac and Conventional Linac

Technology in Cancer Research & Treatment, 2021
In this study, we assess the dosimetric qualities and usability of planning for 1.5 T MR-Linac based intensity modulated radiotherapy (MRL-IMRT) for various clinical sites in comparison with IMRT plans using a conventional linac.
Shouliang Ding MS, Yongbao Li PhD, Hongdong Liu PhD, Rui Li PhD, Bin Wang PhD, Jun Zhang PhD, Yan Chen PhD, Xiaoyan Huang MS   +7 more
doaj   +1 more source

Intrafraction motion and impact of margin reduction for MR‐Linac online adaptive radiotherapy for pancreatic cancer treatments

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 17-24, March 2025.
This analysis included quantification of intrafraction motion in pancreas stereotactic ablative radiotherapy treated on the MR‐Linac, leading to the development of adjusted (PTV) margins. Intrafraction motion indicated an average target displacement of 1–3 mm, resulting in an adjusted PTV margin of 2 mm in the right–left and superior–inferior ...
Ashleigh Fasala, Madeline Carr, Yolanda Surjan, Parmoun Daghigh, Jeremy de Leon, Abbey Burns, Vikneswary Batumalai   +6 more
wiley   +1 more source

Performance of a multileaf collimator system for a 1.5T MR‐linac [PDF]

Medical Physics, 2020
PurposeThe purpose of this study was to evaluate the performance of a multileaf collimator (MLC) system for the high magnetic field of the Elekta Unity magnetic resonance linear accelerator (MR‐linac).MethodsPerformance was evaluated as recommended in AAPM Report Nos. 72 and 142, and MLC motor radiofrequency (RF) shielding was also evaluated. Fields of
Ke, Zhang, Yuan, Tian, Minghui, Li, Kuo, Men, Jianrong, Dai   +4 more
openaire   +2 more sources

Linac-based versus MR-guided SBRT for localized prostate cancer: a comparative evaluation of acute tolerability

, 2023
AimThis study aims to compare acute toxicity of prostate cancer (PCa) stereotactic body radiotherapy (SBRT) delivered by MR-guided radiotherapy (MRgRT) with 1.5-T MR-linac or by volumetric modulated arc (VMAT) with conventional linac.MethodsPatients with
Rosario Mazzola, Rigo, Michele, Niccolò Giaj-Levra, Michele Rigo, Francesco Cuccia, Edoardo Pastorello, Figlia, Vanessa, Filippo Alongi, Alongi, Filippo, Ricchetti, Francesco, Vitale, Claudio, Vanessa Figlia, Ruggero Ruggieri, Pastorello, Edoardo, Francesco Ricchetti, Giaj-Levra, Niccolò, Mazzola, Rosario, Ruggieri, Ruggero, Nicosia, Luca, Luca Nicosia, Claudio Vitale, Cuccia, Francesco   +21 more
core   +1 more source

Individual elective lymph node irradiation for the reduction of complications in head and neck cancer patients (iNode): A phase-I feasibility trial protocol

Clinical and Translational Radiation Oncology, 2023
Introduction: The long-term complication rate in head-and-neck squamous cell carcinoma (HNSCC) patients caused by radiotherapy (RT) can be decreased by restricting elective neck irradiation (ENI) from large adjacent lymph node levels to only individual ...
Floris C.J. Reinders, Mischa de Ridder, Patricia A.H. Doornaert, Cornelis P.J. Raaijmakers, Marielle E.P. Philippens   +4 more
doaj   +1 more source

Translation of dynamic contrast-enhanced imaging onto a magnetic resonance-guided linear accelerator in patients with head and neck cancer

Physics and Imaging in Radiation Oncology
Background and purpose: Magnetic resonance imaging – linear accelerator (MRI-linac) systems permit imaging of tumours to guide treatment. Dynamic contrast enhanced (DCE)-MRI allows investigation of tumour perfusion.
Michael J. Dubec, Michael Berks, James Price, Lisa McDaid, John Gaffney, Ross A. Little, Susan Cheung, Marcel van Herk, Ananya Choudhury, Julian C. Matthews, Andrew McPartlin, Geoff J.M. Parker, David L. Buckley, James P.B. O’Connor   +13 more
doaj   +1 more source

MR‐Linac Successfully Guided the Treatment of a Free‐Moving Mesenteric Mass

Precision Radiation Oncology, EarlyView.
This case demonstrated that a mesenteric tumor could move significantly day‐to‐day in all directions with large volume change. MR‐Linac with online adaptive capability provided a superior platform to treat mobile target with significantly reduced normal tissue exposure to radiation .
Xin Wang, Tze Yee Lim, He Wang, Bouthaina Shbib Dabaja, Jinzhong Yang   +4 more
wiley   +1 more source