Results 31 to 40 of about 151 (141)

Immediate Growth Control in Response to Boiling Histotripsy is Prognostic for Intratumoral Immune Activation

Advanced Science, EarlyView.
Boiling Histrotripsy (BH), a mechanical form of focused ultrasound (FUS), allows for non‐invasive and non‐ionizing tissue destruction. Utilizing a BH treatment protocol that yielded bifurcating primary tumor growth responses, we found that immediate BH‐induced tumor growth control identifies tumors with acute reductions in antigen‐presenting cells (APC)
Lydia E. Kitelinger, Matthew R. DeWitt, Carly M. Van Wagoner, Claire A. Conarroe, Charles C. Funk, Aaron B. Streit, AeRyon Kim, Richard J. Price, Timothy N. J. Bullock   +8 more
wiley   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Symbolic Regression‐Guided Feature Engineering for Predicting Magnetization in Cu‐Based Alloys Under Data‐Scarce Conditions

Materials Genome Engineering Advances, EarlyView.
A symbolic regression approach (SISSO) with physics‐informed feature engineering achieves high‐accuracy prediction of magnetic properties in Cu‐based alloys under data‐scarce conditions. The framework offers an interpretable and transferable strategy for accelerated alloy design.
Buyang Ma, Jiejie Li, Qiuju Zhang, Fenghua Chen, Bo Li, Ziqi Tian, Liang Chen   +6 more
wiley   +1 more source

Design, Analysis, and Experimental Validation of a Variable‐Gap Magnetorheological Damper for Seat Suspension

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT To address the dual challenges of routine driving vibration and impact loads in vehicle seat suspensions, a novel variable‐gap magnetorheological damper (VGMRD) is proposed. By combining a tapered piston with a conformal variable‐diameter cylinder, stroke‐dependent, dual‐mode damping characteristics are achieved without the need for complex ...
Min Wei, Yuchen He, Xiaoting Rui, Yixin Liu, Lilin Gu   +4 more
wiley   +1 more source

LINEAR MR-BRAKE WITH PERMANENT MAGNET ARRAY

, 2022
Currently, MR dampers with electromagnets (EM) are the main type of devices with MR- fluid to provide linear damping and braking forces. The EM devices are simple in structure and easy to control, but consume significant amount of energy and hard to miniaturize.
openaire   +2 more sources

Design and Simulation of Disc-type Magnetorheological Brake based on Rectangular Bump

Jixie chuandong, 2021
Based on the rheological properties of MRF，a disc-type MR brake with rectangular bump is designed，and the calculation formula of its braking torque is derived.
Weicheng Wang, Yiping Luo, Lei Wang, Hao Xiong   +3 more
doaj  

Development of Variable Viscoelastic Joint Module Performance Evaluation and Proposal of Application Examples

Actuators, 2022
With the diversification of robots, modularization of robots has been attracting attention. In our previous study, we developed a robot that mimics the principle of human joint drive using a straight-fiber-type pneumatic rubber artificial muscle ...
Tetsuhito Fujita, Yusuke Shimoda, Katsuki Machida, Manabu Okui, Rie Nishihama, Taro Nakamura   +5 more
doaj   +1 more source

Detecting Loosening of Bolt‐Flanged Pipe Using Smoothed Pseudo Wigner–Ville Distribution: Digital Twin‐Based Approach Using Convolution Neural Networks

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT In this paper, an integrated digital twin‐based fault‐diagnosis framework is proposed to detect bolt loosening in flanged pipe connections. The approach combines finite element‐based numerical modeling, experimental modal analysis, and advanced signal processing‐assisted deep learning to achieve reliable loosening detection under operational ...
Milad Shabani Yousefabad, Behzad Totakhaneh Bonab, Morteza Homayoun Sadeghi, Mir Mohammad Ettefagh, Mohammad Reza Chalak Qazani   +4 more
wiley   +1 more source

Design and development of coil casing MRF brake system

MATEC Web of Conferences, 2017
Nowadays magneto-rheological brakes has been introduce to overcome the drawback of conventional braking such as bulky, leakage and late build up pressure.
Siti Lydia R., Mokhtar R., Muhamad Husaini A.B., Norhaniza B.J.   +3 more
doaj   +1 more source