Results 31 to 40 of about 1,669,562 (240)

Master protocol trial design for technical feasibility of MR-guided radiotherapy [PDF]

, 2022
The master protocol trial design aims to increase efficiency in terms of trial infrastructure and protocol administration which may accelerate development of (technical) innovations in radiation oncology.
Remeijer, P., Heide, U. van der, Triest, B. van, Nowee, M., Marijnen, C., Janssen, T., Sonke, J.J., Couwenberg, A.   +7 more
core   +1 more source

STAT-ART: The Promise and Practice of a Rapid Palliative Single Session of MR-Guided Online Adaptive Radiotherapy (ART)

Frontiers in Oncology, 2019
This work describes a novel application of MR-guided online adaptive radiotherapy (MRgoART) in the management of patients whom urgent palliative care is indicated using statum-adaptive radiotherapy (STAT-ART). The implementation of STAT-ART, as performed
Kathryn E. Mittauer, Kathryn E. Mittauer, Patrick M. Hill, Mark W. Geurts, Mark W. Geurts, Anna-Maria De Costa, Randall J. Kimple, Michael F. Bassetti, John E. Bayouth   +8 more
doaj   +1 more source

DataSheet_1_Case Report: MR-LINAC-guided adaptive radiotherapy for gastric cancer.docx

, 2023
BackgroundThe stomach is one of the most deformable organs. Its shape can be easily affected by breathing movements, and daily diet, and it also varies when the body position is different.
Huadong Wang (291601), Huadong Wang, Fada Guan, Mengyu Zhao, Mengyu Zhao (5876441), Yajun Song (46411), Yajun Song, Jinbo Yue, Jinbo Yue (6067046), Yun Zhang (131894), Zhenjiang Li, Fada Guan (16951974), Zhenjiang Li (1448203), Yun Zhang   +13 more
core   +1 more source

Glycerol-weighted chemical exchange saturation transfer nanoprobes allow 19F/1H dual-modality magnetic resonance imaging-guided cancer radiotherapy

Nature Communications, 2023
Recently, radiotherapy (RT) has entered a new realm of precision cancer therapy with the introduction of magnetic resonance (MR) imaging guided radiotherapy systems into the clinic. Nonetheless, identifying an optimized radiotherapy time window (ORTW) is
Rong A, Haoyu Wang, Chaoqun Nie, Zhaoguo Han, Meifang Zhou, Olagbaju Oluwatosin Atinuke, Kaiqi Wang, Xiance Wang, Shuang Liu, Jingshi Zhao, Wenju Qiao, Xiaohong Sun, Lina Wu, Xilin Sun   +13 more
doaj   +1 more source

Online adaptive MR-guided radiotherapy: Conformity of contour adaptation for prostate cancer, rectal cancer and lymph node oligometastases among radiation therapists and radiation oncologists

Technical Innovations & Patient Support in Radiation Oncology, 2022
Background and purpose: Online adaptive MR-guided treatment planning workflows facilitate daily contour adaptation to the actual anatomy. Allocating contour adaptation to radiation therapists (RTTs) instead of radiation oncologists (ROs) might allow for ...
Marnix J.A. Rasing, Gonda G. Sikkes, Nicole G.P.M. Vissers, Alexis N.T.J. Kotte, Joske H. Boudewijn, Patricia A.H. Doornaert, Wietse S.C. Eppinga, Martijn Intven, Reijer H.A. Rutgers, Annick Scheeren, Louk M.W. Snoeren, Tiny B. Vlig, Jochem R.N. van der Voort van Zyp, Lisa M. Wijkhuizen, Peter S.N. van Rossum, Max Peters, Ina M. Jürgenliemk-Schulz   +16 more
doaj   +1 more source

Case Report: MR-LINAC-guided adaptive radiotherapy for gastric cancer

Frontiers in Oncology, 2023
BackgroundThe stomach is one of the most deformable organs. Its shape can be easily affected by breathing movements, and daily diet, and it also varies when the body position is different.
Yajun Song, Yajun Song, Yun Zhang, Huadong Wang, Huadong Wang, Mengyu Zhao, Fada Guan, Zhenjiang Li, Jinbo Yue   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Noninvasiv sebészet MR-vezérelt fókuszált ultrahanggal: állatkísérletes modellek és klinikai tapasztalatok = Noninvasive surgery using MR-guided focused ultrasound: animal models and clinical experience [PDF]

, 2009
Az MR vezérelt fókuszált ultrahang sebészet (MRgFUS) noninvasiv módon képes a szervezet belsejében daganatos sejteket elpusztítani. Kutatásainkban 1.) állatkísérletes modellen vizsgáltuk az ultrahang kontrasztanyag potencírozó szerepét, valamint 2 ...
Bajzik, Gábor, Balázs, György, Jólesz, Ferenc, Bérczi, Viktor, Belics, Zoran, Hüttl, Kálmán   +5 more
core   +1 more source

Re-irradiation of adrenal metastases using MR-guided adaptive SABR: A feasible and effective approach in a high-risk population

Clinical and Translational Radiation Oncology
Re-irradiation of adrenal metastases is challenging due to cumulative dose constraints. We present seven patients treated with MR-guided adaptive stereotactic ablative radiotherapy (SABR), leveraging real-time imaging and on-table adaptation for precise ...
Miguel A. Palacios, Anna M.E. Bruynzeel, Peter S.N. van Rossum, Omar Bohoudi, Suresh Senan, Famke L. Schneiders   +5 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source