Results 51 to 60 of about 1,669,562 (240)

A body mass index-based method for “MR-only” abdominal MR-guided adaptive radiotherapy

Zeitschrift für Medizinische Physik
Purpose: Dose calculation for MR-guided radiotherapy (MRgRT) at the 0.35 T MR-Linac is currently based on deformation of planning CTs (defCT) acquired for each patient.
Carolin Rippke, C. Katharina Renkamp, Christiane Stahl-Arnsberger, Annette Miltner, Carolin Buchele, Juliane Hörner-Rieber, Jonas Ristau, Jürgen Debus, Markus Alber, Sebastian Klüter   +9 more
doaj   +1 more source

Online adaptive radiotherapy for head and neck cancers on the MR linear Accelerator: Introducing a novel modified Adapt-to-Shape approach

Clinical and Translational Radiation Oncology, 2022
Introduction: The Elekta Unity MR-Linac (MRL) has enabled adaptive radiotherapy (ART) for patients with head and neck cancers (HNC). Adapt-To-Shape-Lite (ATS-Lite) is a novel Adapt-to-Shape strategy that provides ART without requiring daily clinician ...
Amit Gupta, Alex Dunlop, Adam Mitchell, Dualta McQuaid, Simeon Nill, Helen Barnes, Kate Newbold, Chris Nutting, Shreerang Bhide, Uwe Oelfke, Kevin Joseph Harrington, Kee Howe Wong   +11 more
doaj   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Achievement of the Ideal Outcome After Pancreatectomy for Pancreatic Ductal Adenocarcinoma Is Associated With Earlier Initiation and Higher Completion Rates of Adjuvant Chemotherapy and Improved Long‐Term Survival

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background The Ideal Outcome is a composite quality indicator reflecting optimal postoperative course after pancreatic surgery. This study aimed to clarify the prognostic significance of achieving the Ideal Outcome and its influence on the initiation and completion of adjuvant chemotherapy.
Ryosuke Fukushima, Kenichiro Araki, Ryo Muranushi, Kouki Hoshino, Kei Hagiwara, Shunsuke Kawai, Mariko Tsukagoshi, Takamichi Igarashi, Norio Kubo, Ken Shirabe   +9 more
wiley   +1 more source

Novel modified patient immobilisation device with an integrated coil support system for MR-guided online adaptive radiotherapy in the management of brain and head-and-neck tumours

Technical Innovations & Patient Support in Radiation Oncology, 2021
Magnetic resonance imaging (MR)-guided online adaptive radiotherapy is a promising technique in the field of radiation oncology providing excellent visualisation of soft-tissues, and allowing for online plan adaptation and tumour tracking.
Dinah Konnerth, Chukwuka Eze, Lukas Nierer, Patrick Thum, Juliane Braun, Maximilian Niyazi, Claus Belka, Stefanie Corradini   +7 more
doaj   +1 more source

Soft-tissue prostate intrafraction motion tracking in 3D cine-MR for MR-guided radiotherapy [PDF]

, 2019
To develop a method to automatically determine intrafraction motion of the prostate based on soft tissue contrast on 3D cine-magnetic resonance (MR) images with high spatial and temporal resolution.
Lagendijk, Jan J W, van der Voort van Zyp, Jochem R N, Maspero, Matteo, de Boer, J C J, de Muinck Keizer, Daan M, Van den Berg, Cornelis A T, Voort van Zyp, J.R.N. van der, Maspero, M., Raaymakers, Bas W, Kerkmeijer, L.G.W., Lagendijk, J.J., Boer, J.C. den, Berg, C.A.T. van den, Raaymakers, B.W., Andreychenko, A., Andreychenko, Anna, Kerkmeijer, Linda G W, Keizer, D.M. de Muinck   +17 more
core   +1 more source

Timing of Work‐Rest Implementation Influences Worker Productivity Under Heat Stress: Evidence for Initial Stay Time‐Based Scheduling

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Introduction Work‐rest allocations recommended by the American Conference of Governmental Industrial Hygienists (ACGIH) limit heat strain and are typically implemented from the onset of work. Whether delaying implementation until after the initial stay time (IST; the duration of continuous work before core temperature reaches 38.0°C) improves ...
Glen P. Kenny, Kelli E. McCormick, Katie E. Wagar, Roberto C. Harris‐Mostert, James J. McCormick, Leonidas G. Ioannou, Fergus K. O'Connor   +6 more
wiley   +1 more source

Zebrafish xenograft models as a fast platform for metastasis diagnosis and cisplatin response of head and neck squamous cell carcinoma

Animal Models and Experimental Medicine, EarlyView.
A zebrafish xenograft model accurately distinguishes metastatic from non‐metastatic HNSCC and recapitulates cisplatin sensitivity/resistance patterns. Using patient‐derived tumors, it predicts individual therapeutic responses, offering a rapid, clinically applicable platform for guiding personalized treatment. Abstract Background Head and neck squamous
Lu Chen, Shu Sun, Yujia Liu, Liehao Jiang, Cuiyun Wu, Ting Liu, Yujiao Zhao, Yuwei Liu, Lu Liu, Qi Wang, Xiaowei Zheng, Ping Huang   +11 more
wiley   +1 more source

Characterization of spatial integrity with active and passive implants in a low-field magnetic resonance linear accelerator scanner

Physics and Imaging in Radiation Oncology
Background and Purpose: Standard imaging protocols can guarantee the spatial integrity of magnetic resonance (MR) images utilized in radiotherapy. However, the presence of metallic implants can significantly compromise this integrity. Our proposed method
Bertrand Pouymayou, Yoel Perez-Haas, Florin Allemann, Ardan M. Saguner, Nicolaus Andratschke, Matthias Guckenberger, Stephanie Tanadini-Lang, Lotte Wilke   +7 more
doaj   +1 more source

Enhanced MRI-guided radiotherapy with gadolinium-based nanoparticles: preclinical evaluation with an MRI-linac

Cancer Nanotechnology, 2020
Background The AGuIX® (NH TherAguix) nanoparticle has been developed to enhance radiotherapy treatment and provide strong MR contrast. These two properties have previously been investigated separately and progressed to clinical trial following a clinical
H. L. Byrne, G. Le Duc, F. Lux, O. Tillement, N. M. Holmes, A. James, U. Jelen, B. Dong, G. Liney, T. L. Roberts, Z. Kuncic   +10 more
doaj   +1 more source