Results 81 to 90 of about 96,614 (276)

CPP–PEG‐Guided Surface Engineering of Mitochondria Enables Efficient Cellular Uptake and Respiratory Modulation

Advanced Materials Interfaces, EarlyView.
PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi, Yukari Muramatsu, Akihiro Nakaya, Yuji Maruo, Rick C. Tsai, Masashi Suganuma, Hisashi Ohta, Atsuhito Takeda, Hideyoshi Harashima, Yuma Yamada   +9 more
wiley   +1 more source

Risk factors of disease severity and mechanical ventilation requirement in childhood Guillain-Barré Syndrome

The Turkish Journal of Pediatrics
Background. This study aimed to investigate the risk factors associated with the severity of the disease, the need for mechanical ventilation (MV) and poor prognosis in the early stages of Guillain-Barré Syndrome (GBS). Methods.
Gül Yücel, Ahmet Kadir Arslan, Bilge Özgör, Serdal Güngör   +3 more
doaj   +1 more source

Need for large scale randomised evidence about lowering LDL cholesterol in people with diabetes mellitus: MRC/BHF heart protection study and other major trials [PDF]

Heart, 2000
Diabetes mellitus contributes substantially to the global burden of disease, with an estimated 100 million people affected worldwide, and its prevalence is increasing rapidly.1 Macrovascular complications are among the chief causes of major morbidity in people with diabetes, and most of their deaths are attributed to cardiovascular causes.2 3 In type 2
Armitage, J, Collins, R
openaire   +3 more sources

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

Hepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues   +16 more
wiley   +1 more source

Multipoint incremental motor unit number estimation versus amyotrophic lateral sclerosis functional rating scale and the medical research council sum score as an outcome measure in amyotrophic lateral sclerosis

Annals of Indian Academy of Neurology, 2014
Introduction: Monitoring the disease progression in amyotrophic lateral sclerosis (ALS) is a challenge due to different rates of progression between patients.
Sujit Abajirao Jagtap, Abraham Kuruvilla, Preetha Govind, Muralidharan D Nair, C Sarada, Ravi Prasad Varma   +5 more
doaj   +1 more source

Is the NEI-VFQ-25 a useful tool in identifying visual impairment in an elderly population? [PDF]

, 2006
BACKGROUND: The use of self-report questionnaires to substitute for visual acuity measurement has been limited. We examined the association between visual impairment and self reported visual function in a population sample of older people in the UK ...
Fletcher, AE, Evans, JR, Wormald, Richard PL, Rudnicka, AR, Fletcher, Astrid E, Smeeth Liam, Rudnicka, Alicja R, Alicja R Rudnicka, Wormald Richard PL, Jennifer R Evans, Fletcher Astrid E, Rudnicka Alicja R, Owen, Christopher G, Liam Smeeth, Richard PL Wormald, Astrid E Fletcher, Evans, Jennifer R, Evans Jennifer R, Smeeth, Liam, Owen, CG, Owen Christopher G, Smeeth, L, Christopher G Owen, Wormald, RP   +23 more
core   +1 more source

Muscle Control of an Extra Robotic Digit

Advanced Robotics Research, EarlyView.
This study compares muscle‐ and movement‐based control for operating a supernumerary robotic thumb. While movement control performs better in the proposed tasks, muscle‐based (EMG) control promotes broader motor learning. The results highlight the promise and challenges of using biosignals for human augmentation, offering new insights into intuitive ...
Julien Russ, Lucy Dowdall, Francesco Cenciarelli, Kitty Goodridge, Mabel Ziman, Hristo Dimitrov, Danielle Clode, Tamar R. Makin   +7 more
wiley   +1 more source

DNA‐mimic for Specific Surface Functionalization of Zr‐MOFs for Bacterial Targeting

Angewandte Chemie, EarlyView.
We introduce phosphotyrosine‐modified PNA as a superior, single‐step post‐synthesis surface coating for PCN‐222. The DNA mimic allows for controlled post‐functionalization with single‐stranded DNA for the attachment of protein moieties for bacterial targeting. ABSTRACT Nanosized metal–organic frameworks (MOFs) are versatile platforms used in biomedical
Anna Scheeder, Jon Ostolaza‐Paraiso, Andrew G. Baker, Juan F. Blandez, Georgina E. Lindop, Simon M. Fairclough, Ljiljana Fruk, Ioanna Mela, David Fairen‐Jimenez, Clemens F. Kaminski   +9 more
wiley   +2 more sources

Slow and fast adaptive modulation and coding for uplink massive MIMO systems with packet retransmission

IET Communications, 2022
Here, the authors consider the uplink of a cellular massive multiple‐input multiple‐output (MIMO) system with maximum ratio combiner (MRC) at base stations (BSs).
Amin Radbord, Jalil S. Harsini
doaj   +1 more source