Results 131 to 140 of about 97,528 (241)

The Effect of Magnetic Field Gradient and Gadolinium-Based MRI Contrast Agent Dotarem on Mouse Macrophages. [PDF]

Cells, 2022
Chanana P, Uosef A, Vaughn N, Suarez-Villagran M, Ghobrial RM, Kloc M, Wosik J.   +6 more
europepmc   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

Effect of sampling volume on measurements of size and chemical homogeneity of MRI contrast agent FeraSpin™ R. [PDF]

Nanoscale Adv
Maceratesi V, Doveri LR, Engel N, Cantoni E, Pallavicini P, Milanese C, Sack F, Gehrke N, Briel A, Lambeng N, Douri S, Chivas-Joly C, Alasonati E, de Carsalade du Pont V, Sapalidis D, Gerina M, Silva BFB, Tache O, Lee WA, Cant DJH, Minelli C, Gollwitzer C, Schürmann R, Diaz Fernandez YA.   +23 more
europepmc   +1 more source

A DNA-Based MRI Contrast Agent for Quantitative pH Measurement. [PDF]

ACS Sens, 2021
Seo H, Ma KY, Tuttle EE, Calderon IAC, Buskermolen AD, Flask CA, Clark HA.   +6 more
europepmc   +1 more source

Convergent and Divergent Connectivity Patterns of the Arcuate Fasciculus in Macaques and Humans

Advanced Science, EarlyView.
This study employs viral‐based single‐neuron tracing and dMRI‐based whole‐brain tractography to investigate arcuate fasciculus (AF) trajectories in macaque monkeys, and compares with the human AF connectome using spectral embedding. Results demonstrate conserved AF topography spanning temporoparietal‐auditory‐frontal pathways across primates, with ...
Jiahao Huang, Ruifeng Li, Wenwen Yu, Anan Li, Xiangning Li, Mingchao Yan, Lei Xie, Qingrun Zeng, Xueyan Jia, Shuxin Wang, Ronghui Ju, Feng Chen, Qingming Luo, Hui Gong, Andrew Zalesky, Xiaoquan Yang, Yuanjing Feng, Zheng Wang   +17 more
wiley   +1 more source

Development of an MRI contrast agent for both detection and inhibition of the amyloid-β fibrillation process. [PDF]

RSC Adv, 2022
Utomo RY, Okada S, Sumiyoshi A, Aoki I, Nakamura H.   +4 more
europepmc   +1 more source

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Pharmacokinetics, Excretion, and Organ Distribution of the Novel Gadolinium-Based MRI Contrast Agent Gadoquatrane in Female Cynomolgus Monkeys. [PDF]

Invest Radiol
Guenther C, Frenzel T, Rottmann A, Lohrke J, Janssen W.   +4 more
europepmc   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

¹H/¹⁵N NMR and Low-Field ¹H MRI of SABRE-Hyperpolarized Pyrazinamide─An Approved Antibiotic and Potential MRI Contrast Agent. [PDF]

J Phys Chem B
Siraj Z, Petrilla AF, Senanayake IM, Iqbal N, Gyesi JN, Westerfield J, Daluwathumullagamage PJ, Shchepin RV, Ragunathan S, Chekmenev EY, Goodson BM.   +10 more
europepmc   +1 more source