Results 21 to 30 of about 19,153 (149)

Taste aversion learning in autoimmune MRL-lpr/lpr and Mrl +/+ mice

open access: yesBrain, Behavior, and Immunity, 1987
Conditioned taste aversion to a neutral stimulus paired with an immunosuppressive drug (cyclophosphamide) was assessed in lupus-prone MRL-lpr/lpr and congenic control (MRL +/+) mice. The presence of lymphoproliferation in MRL-lpr/lpr mice was associated with poorer taste aversion learning and varied as a function of the dose of cyclophosphamide.
L J, Grota, R, Ader, N, Cohen
openaire   +2 more sources

Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial

open access: yesCritical Care, 2021
Background Ceftolozane/tazobactam is approved for treatment of hospital-acquired/ventilator-associated bacterial pneumonia (HABP/VABP) at double the dose approved for other infection sites.
Jean-François Timsit   +14 more
doaj   +1 more source

BioPhi: A platform for antibody design, humanization, and humanness evaluation based on natural antibody repertoires and deep learning

open access: yesmAbs, 2022
Despite recent advances in transgenic animal models and display technologies, humanization of mouse sequences remains one of the main routes for therapeutic antibody development.
David Prihoda   +6 more
doaj   +1 more source

Residues of Fluoroquinolone Antibiotics Induce Carbonylation and Reduce In Vitro Digestion of Sarcoplasmic and Myofibrillar Beef Proteins

open access: yesFoods, 2020
Although the impact of oxidation on human health has been of growing interest, the oxidation of proteins, major component of meat, has received little attention.
Johana Márquez-Lázaro   +2 more
doaj   +1 more source

Heart regeneration in adult MRL mice [PDF]

open access: yesProceedings of the National Academy of Sciences, 2001
The reaction of cardiac tissue to acute injury involves interacting cascades of cellular and molecular responses that encompass inflammation, hormonal signaling, extracellular matrix remodeling, and compensatory adaptation of myocytes. Myocardial regeneration is observed in amphibians, whereas scar formation characterizes cardiac ventricular wound
J M, Leferovich   +6 more
openaire   +2 more sources

The impact and cost-effectiveness of 9-valent human papillomavirus vaccine in adolescent females in Hong Kong

open access: yesCost Effectiveness and Resource Allocation, 2021
Introduction In Hong Kong (HK), a single-cohort vaccination program for 10–12-year-old girls with the 9-valent human papillomavirus (HPV) vaccine (9vHPV; types 6/11/16/18/31/33/45/52/58) has been launched. This study assessed the public health impact and
Tak Hong Cheung   +7 more
doaj   +1 more source

PINES: phenotype-informed tissue weighting improves prediction of pathogenic noncoding variants

open access: yesGenome Biology, 2018
Functional characterization of the noncoding genome is essential for biological understanding of gene regulation and disease. Here, we introduce the computational framework PINES (Phenotype-Informed Noncoding Element Scoring), which predicts the ...
Corneliu A. Bodea   +5 more
doaj   +1 more source

MANAGEMENT OF PESTICIDE CONTAMINATION IN THE ENVIRONMENT AND AGRICULTURAL PRODUCTS: A LITERATURE REVIEW

open access: yesJurnal Kesehatan Lingkungan, 2022
Introduction: The use of pesticides not only has benefits for product growth but also causes problems with the entry of pesticide residues in the food chain to pollution to the environment.
Globila Nurika   +3 more
doaj   +1 more source

Pesticide residues in vegetables in four regions of Jilin Province

open access: yesInternational Journal of Food Properties, 2020
A study of pesticide residues was investigated in vegetable samples to highlight the trend of drugs obtained from the Jilin Province, China. Total of 230 samples obtained from four regions over the period 2016–2017 were screened for 18 pesticides that ...
Di Hu   +6 more
doaj   +1 more source

Effects of Brining and Picking Time on The Degradation of Pesticide Residue in Grapevine Leaves

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2019
Intensive pesticide use in vineyard resulted in residue problem on vine leaves that are used as food. This study was aimed at development of a proper chemical control program to reduce the pesticide residue problem on vine (cv.
Rüstem Cangi   +2 more
doaj   +1 more source

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