Results 71 to 80 of about 88,502 (304)
Advanced Science, 2020 The past decade has seen the materialization of immune checkpoint blockade as an emerging approach to cancer treatment. However, the overall response and patient survival are still modest. Various efforts to study the “cancer immunogram” have highlighted
Jun Xu +4 more
doaj +1 more source
npj Vaccines, 2021 Vaccine efficacy is often assessed by counting disease cases in a clinical trial. A new quantitative framework proposed here (“PoDBAY,” Probability of Disease Bayesian Analysis), estimates vaccine efficacy (and confidence interval) using immune response ...
Julie Dudášová +8 more
doaj +1 more source
Uncovering Neural Scaling Laws in Molecular Representation Learning [PDF]
arXiv, 2023 Molecular Representation Learning (MRL) has emerged as a powerful tool for drug and materials discovery in a variety of tasks such as virtual screening and inverse design. While there has been a surge of interest in advancing model-centric techniques, the influence of both data quantity and quality on molecular representations is not yet clearly ...
arxiv
FEBS Letters, 2001 MRL mice bearing the lpr (Fas) or gld (Fas ligand) mutation, MRL‐Faslpr or MRL‐FasLgld , respectively, develop arthritis similar to rheumatoid arthritis, but C3H and C57BL/6 mice bearing such mutations do not. In MRL‐Faslpr mice, agalactosylated oligosaccharides in serum IgG increase significantly in comparison to MRL‐+/+ mice without arthritis.
Munehiro Nakata +4 more
openaire +3 more sources
Acta Pharmacologica Sinica, 2015 Aim:A number of evidence shows that the differentiation of B lymphocytes into plasma cells plays an important role in lupus pathogenesis. In this study we investigated how prednisone, a classical therapeutic drug for autoimmune diseases, regulated plasma
Shangxue Yan +4 more
semanticscholar +1 more source
Julius-Kühn-Archiv, 2020 A new study design, according to the guideline SANTE11956/2016 rev:9 (2018), was established to determine the maximum residue level (MRL) of plant protection products in honey.
Cohen, Yotam +3 more
doaj +1 more source
Communications Biology, 2021 Furse et al. use a purpose-built computational tool called Lipid Traffic Analysis to determine the spatial distribution of lipids throughout an organism.
Samuel Furse +6 more
doaj +1 more source
Applied Sciences, 2023 Hard turning is an emerging machining technology that evolved as a substitute for grinding in the production of precision parts from hardened steel. It offers advantages such as reduced cycle times, lower costs, and environmental benefits over grinding ...
Saswat Khatai +3 more
doaj +1 more source
Hyperparameter-free losses for model-based monocular reconstruction [PDF]
, 2019 This work proposes novel hyperparameter-free losses for single view 3D reconstruction with morphable models (3DMM). We dispense with the hyperparameters used in other works by exploiting geometry, so that the shape of the object and the camera pose are ...
Batard, Thomas +3 more
core +2 more sources
Oocytes in Newborn MRL Mouse Testes1 [PDF]
Biology of Reproduction, 2008 Although mammals produce either sperm or eggs depending on their sex, we found oocytes in the testes of newborn MRL/MpJ male mice. In the present study, we report the morphological characteristics of testicular oocytes, the postnatal change of oocyte number per testis, and the expression of a few oocyte-specific genes in the testes of MRL/MpJ mice. The
Akihiro Konno +5 more
openaire +3 more sources