Results 121 to 130 of about 2,030,676 (220)
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl +10 more
wiley +1 more source
Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke
Objectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Mialitiana Solo Nomenjanahary +21 more
wiley +1 more source
MAGNETIC RESONANCE LYMPHOGRAPHY (MRL): POINT AND COUNTER-POINT
Two preeminent lymphologists debatethe findings, implications, interpretations, andvalue of magnetic resonance lymphography(MRL) in the evaluation of peripherallymphedema.
Olszewski, W
core +1 more source
MARCH5 Links Hypoxia to Neutrophil Ferroptosis in SLE via FSP1 Ubiquitination
ABSTRACT Purpose Ferroptosis plays an important role in the progression of systemic lupus erythematosus (SLE). This study aims to investigate the molecular mechanism by which membrane‐associated RING‐CH‐type finger protein 5 (MARCH5) regulates ferroptosis suppressor protein 1 (FSP1), a key regulator of ferroptosis resistance, under hypoxic conditions ...
Jing Zhang +3 more
wiley +1 more source
Cronología del MRL y contextos históricos
Cronología del Movimiento Revolucionario Liberal (MRL) 1957-1967Chronology of the Liberal Revolutionary Movement (MRL) 1957 ...
Arango Jaramillo, Mario +1 more
core
ABSTRACT The incidence of human papillomavirus‐positive (HPV+) oropharyngeal cancer (OPC) has increased rapidly, and HPV early antigen serology has been proposed as a scalable and cost‐effective early detection test. HPV seropositivity can precede clinical presentation of OPC by several years, so additional surveillance procedures may be necessary to ...
Lucas Penny +23 more
wiley +1 more source
MRL, apple, cherry, export, Farm Management, International relations/trade, crop production/industries,
Thornsbury, Suzanne, Takagi, Chifumi
core
Alteration of DNA methylation levels in MRL lupus mice
SUMMARY Recent reports suggest that DNA methylation is involved in the cause of autoimmune disease. We investigated the alteration of DNA methylation levels in lupus strains of mice, MRL/lpr as a model, which develop an age-dependent ...
T YAMAGUCHI +6 more
core +1 more source
Half a Century of Per‐ and Polyfluoroalkyl Substances in Northern Gannet Eggs: Impact of Regulations
ABSTRACT Per‐ and polyfluoroalkyl substances (PFAS), known as “forever chemicals”, are persistent organic pollutants that have been widely used in the industry across the globe for many decades. Their chemical stability, bioaccumulation, and toxicity pose major environmental and health risks. This study examines temporal trends in the concentrations of
Anaïs Fournier +2 more
wiley +1 more source
Abnormal IgG galactosylation in MRL-lpr/lpr mice: pathogenic role in the development of arthritis
MRL-lpr/lpr (MRL/lpr) mice spontaneously develop arthritis by an increase in the incidence of agalactosylated oligosaccharides in serum IgG, similar to rheumatoid arthritis patients.
Kuroda, Yasuhiro +7 more
core

