Results 121 to 130 of about 2,030,676 (220)

Neurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development

open access: yesAnnals of Neurology, Volume 100, Issue 5, Page 948-961, November 2026.
Objective Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...
Marlene Tahedl   +10 more
wiley   +1 more source

Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke

open access: yesAnnals of Neurology, Volume 100, Issue 5, Page 964-978, November 2026.
Objectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Mialitiana Solo Nomenjanahary   +21 more
wiley   +1 more source

MAGNETIC RESONANCE LYMPHOGRAPHY (MRL): POINT AND COUNTER-POINT

open access: yes, 2013
Two preeminent lymphologists debatethe findings, implications, interpretations, andvalue of magnetic resonance lymphography(MRL) in the evaluation of peripherallymphedema.
Olszewski, W
core   +1 more source

MARCH5 Links Hypoxia to Neutrophil Ferroptosis in SLE via FSP1 Ubiquitination

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.
ABSTRACT Purpose Ferroptosis plays an important role in the progression of systemic lupus erythematosus (SLE). This study aims to investigate the molecular mechanism by which membrane‐associated RING‐CH‐type finger protein 5 (MARCH5) regulates ferroptosis suppressor protein 1 (FSP1), a key regulator of ferroptosis resistance, under hypoxic conditions ...
Jing Zhang   +3 more
wiley   +1 more source

Cronología del MRL y contextos históricos

open access: yes, 1999
Cronología del Movimiento Revolucionario Liberal (MRL) 1957-1967Chronology of the Liberal Revolutionary Movement (MRL) 1957 ...
Arango Jaramillo, Mario   +1 more
core  

HPV Serology and Circulating Viral DNA for Detection, Genotyping, and Measurement of Disease Burden in Oropharyngeal Cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 9, Page 2336-2346, 1 November 2026.
ABSTRACT The incidence of human papillomavirus‐positive (HPV+) oropharyngeal cancer (OPC) has increased rapidly, and HPV early antigen serology has been proposed as a scalable and cost‐effective early detection test. HPV seropositivity can precede clinical presentation of OPC by several years, so additional surveillance procedures may be necessary to ...
Lucas Penny   +23 more
wiley   +1 more source

Japan MRL Regulation [PDF]

open access: yes
MRL, apple, cherry, export, Farm Management, International relations/trade, crop production/industries,
Thornsbury, Suzanne, Takagi, Chifumi
core  

Alteration of DNA methylation levels in MRL lupus mice

open access: yes, 1997
SUMMARY Recent reports suggest that DNA methylation is involved in the cause of autoimmune disease. We investigated the alteration of DNA methylation levels in lupus strains of mice, MRL/lpr as a model, which develop an age-dependent ...
T YAMAGUCHI   +6 more
core   +1 more source

Half a Century of Per‐ and Polyfluoroalkyl Substances in Northern Gannet Eggs: Impact of Regulations

open access: yesJournal of Applied Toxicology, Volume 46, Issue 11, Page 4085-4098, November 2026.
ABSTRACT Per‐ and polyfluoroalkyl substances (PFAS), known as “forever chemicals”, are persistent organic pollutants that have been widely used in the industry across the globe for many decades. Their chemical stability, bioaccumulation, and toxicity pose major environmental and health risks. This study examines temporal trends in the concentrations of
Anaïs Fournier   +2 more
wiley   +1 more source

Abnormal IgG galactosylation in MRL-lpr/lpr mice: pathogenic role in the development of arthritis

open access: yes, 2001
MRL-lpr/lpr (MRL/lpr) mice spontaneously develop arthritis by an increase in the incidence of agalactosylated oligosaccharides in serum IgG, similar to rheumatoid arthritis patients.
Kuroda, Yasuhiro   +7 more
core  

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