Results 131 to 140 of about 1,739,896 (229)

Availability and Quality of Electronic Health Record Data to Track Physical Function Across a Care Transition

open access: yesLearning Health Systems, Volume 10, Issue 4, October 2026.
ABSTRACT Introduction Physical function (PF) is critical to quality of life and healthcare value, especially for older adults following hospitalization. Monitoring PF supports recovery, reduces adverse events, and improves care transitions. Despite the potential of electronic health records (EHRs) enabling systematic PF tracking, such data are rarely ...
Robin L. Marcus   +6 more
wiley   +1 more source

Impact of Stabilizing Osmolytes on the Conformational Dynamics of Human and Rat Islet Amyloid Polypeptides

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 10, Page 1717-1737, October 2026.
ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman   +3 more
wiley   +1 more source

DLK1-Dio3 miRNAs are highly upregulated in splenic cells from MRL-lpr lupus mice when compared to control MRL mice.

open access: yes, 2016
The miRNA expression in splenocytes (A), purified splenic CD4+ T cells (B), CD19+ B cells (C), and double negative effluent fraction splenic CD4-CD19- cells (D) from MRL and MRL-lpr mice (13–16 wks old) were quantified by Taqman miRNA assays.
Rujuan Dai (80849)   +2 more
core   +1 more source

A Review of Nonsteroidal Anti‐Inflammatory Drugs for Food‐Producing Animals With a Focus on Potential Applications for Farmed Finfish

open access: yesJournal of Fish Diseases, Volume 49, Issue 10, October 2026.
ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English   +4 more
wiley   +1 more source

Scientific support for preparing an EU position in the 56th Session of the Codex Committee on Pesticide Residues (CCPR)

open access: yesEFSA Journal
The European Commission asked EFSA to provide support in the framework of Article 43 of Regulation (EC) No 396/2005 for the preparation of the EU position for 56th Session of the Codex Committee on Pesticide Residues (CCPR).
EFSA (European Food Safety Authority)
doaj   +1 more source

A trait‐based integration of competition and abiotic tolerance underlies plant success

open access: yesNew Phytologist, Volume 252, Issue 1, Page 87-99, October 2026.
Competitive effect and abiotic tolerance show positive associations with species' niche breadth and local dominance. Summary Understanding what determines species' ecological success is a central challenge in ecology. Competitive ability and abiotic tolerance are expected to be strong predictors of species success, yet theory predicts a trade‐off ...
Jan Douda   +7 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, Volume 20, Issue 9, Page 2203-2219, September 2026.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, Volume 20, Issue 9, Page 2188-2202, September 2026.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Large scale retrieval for the LinkedIn feed using causal language models

open access: yesAI Magazine, Volume 47, Issue 3, Fall 2026.
Abstract In large‐scale recommendation systems like LinkedIn's, the retrieval stage is critical for narrowing billions of potential candidates to a manageable subset for ranking. LinkedIn's feed now serves suggested content based on the topical interests of members, where 2000 candidates are retrieved from several million candidates with a latency ...
Sudarshan Srinivasa Ramanujam   +23 more
wiley   +1 more source

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