Results 131 to 140 of about 1,739,896 (229)
ABSTRACT Introduction Physical function (PF) is critical to quality of life and healthcare value, especially for older adults following hospitalization. Monitoring PF supports recovery, reduces adverse events, and improves care transitions. Despite the potential of electronic health records (EHRs) enabling systematic PF tracking, such data are rarely ...
Robin L. Marcus +6 more
wiley +1 more source
ABSTRACT The aggregation of human islet amyloid polypeptide (hIAPP) into cytotoxic oligomers and amyloid fibrils is a hallmark of type 2 diabetes mellitus (T2DM), leading to pancreatic β‐cell dysfunction. In contrast, rat IAPP (rIAPP) is largely non‐amyloidogenic. Osmolytes such as glucose, glycerol, and sorbitol are known to stabilize globular protein
Kiara A. Kidman +3 more
wiley +1 more source
The miRNA expression in splenocytes (A), purified splenic CD4+ T cells (B), CD19+ B cells (C), and double negative effluent fraction splenic CD4-CD19- cells (D) from MRL and MRL-lpr mice (13–16 wks old) were quantified by Taqman miRNA assays.
Rujuan Dai (80849) +2 more
core +1 more source
ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English +4 more
wiley +1 more source
The European Commission asked EFSA to provide support in the framework of Article 43 of Regulation (EC) No 396/2005 for the preparation of the EU position for 56th Session of the Codex Committee on Pesticide Residues (CCPR).
EFSA (European Food Safety Authority)
doaj +1 more source
A trait‐based integration of competition and abiotic tolerance underlies plant success
Competitive effect and abiotic tolerance show positive associations with species' niche breadth and local dominance. Summary Understanding what determines species' ecological success is a central challenge in ecology. Competitive ability and abiotic tolerance are expected to be strong predictors of species success, yet theory predicts a trade‐off ...
Jan Douda +7 more
wiley +1 more source
Modification of the existing MRLs for spirotetramat in onions and the setting of new MRLs in kidney [PDF]
openaire +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Large scale retrieval for the LinkedIn feed using causal language models
Abstract In large‐scale recommendation systems like LinkedIn's, the retrieval stage is critical for narrowing billions of potential candidates to a manageable subset for ranking. LinkedIn's feed now serves suggested content based on the topical interests of members, where 2000 candidates are retrieved from several million candidates with a latency ...
Sudarshan Srinivasa Ramanujam +23 more
wiley +1 more source

