Results 61 to 70 of about 6,871 (234)

Abnormal IgG galactosylation and arthritis in MRL‐Fas^lpr or MRL‐FasL^gld mice are under the control of the MRL genetic background

FEBS Letters, 2001
MRL mice bearing the lpr (Fas) or gld (Fas ligand) mutation, MRL‐Faslpr or MRL‐FasLgld , respectively, develop arthritis similar to rheumatoid arthritis, but C3H and C57BL/6 mice bearing such mutations do not. In MRL‐Faslpr mice, agalactosylated oligosaccharides in serum IgG increase significantly in comparison to MRL‐+/+ mice without arthritis.
Kuroda, Yasuhiro, Nakata, Munehiro, Nose, Masato, Kojima, Naoya, Mizuochi, Tsuguo   +4 more
openaire   +2 more sources

TWEAK/Fn14 Signaling Drives Oxidative Cardiac Injury in Systemic Lupus Erythematosus: Evidence From Patient Biomarker Studies, Lupus Mouse Models, and Cardiomyocyte Assays

Arthritis &Rheumatology, EarlyView.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu, Zhu Yan, Xueting Peng, Meixuan Li, Juan Wang, Yan Zhang, Xiaoqian Hu, Mingzhu Zhou, Kaixuan Ren, Dan Zhang, Xingyi Guo, Yumin Xia, Huanhuan Huo   +12 more
wiley   +1 more source

Safety levels for organophosphate pesticide residues on fruits, vegetables, and nuts

International Journal of Food Contamination, 2019
A novel approach is developed to establish safety levels for organophosphate pesticides residues present in 80 fruit, vegetable, and nut commodities. These levels, known as Pesticide Safety Levels (PSL), represent the concentration of the organophosphate
Elizabeth A. Jara, Carl K. Winter
doaj   +1 more source

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi, Seyoung Jung, Jeong Ho Joo, Young‐Eun Kim, Heounjeong Go, Yong‐Gil Kim, Chang‐Keun Lee, Bin Yoo, Jeong Seok Lee, Seokchan Hong   +9 more
wiley   +1 more source

Updated peer review of the pesticide risk assessment of the active substance trinexapac (variant evaluated trinexapac‐ethyl)

EFSA Journal, 2023
The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Lithuania, and co‐rapporteur Member State, Latvia, for the ...
European Food Safety Authority (EFSA), Fernando Alvarez, Maria Arena, Domenica Auteri, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Christopher Lythgo, Oriol Magrans, Iris Mangas, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Agnès Rortais, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andras Szoradi, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, Laura Villamar‐Bouza   +46 more
doaj   +1 more source

Voluntary consumption of cyclophosphamide by Mrl mice

Brain, Behavior, and Immunity, 1989
Fluid-deprived, lupus-prone Mrl-lpr/lpr and congenic Mrl +/+ mice were provided with a single drinking bottle containing varying concentrations of cyclophosphamide (CY) dissolved in chocolate milk. Eighteen- and 20-week-old Mrl-lpr/lpr males with manifest symptoms of autoimmune disease voluntarily consumed more of the CY solution than Mrl +/+ mice of ...
L J, Grota, T R, Schachtman, J A, Moynihan, N, Cohen, R, Ader   +4 more
openaire   +2 more sources

The Tendon‐to‐Bone Seam: A Transtendinous Approach to Rotator Cuff Repair

Arthroscopy Techniques, EarlyView.
Abstract This technique article describes the tendon‐to‐bone seam technique, a knotless, transtendinous approach to arthroscopic rotator cuff repair. The technique employs a single‐use deployment device preloaded with multiple PEEK anchors interconnected with a single polyethylene #2 suture, enabling the surgeon to create a continuous “seam” of ...
James Tyler Frix, Ryan Serbin, Howard W. Harris, Marc R. Labbe, Patrick M. Connor   +4 more
wiley   +1 more source

Perceptions of the Muslim religious leaders and their attitudes on herbal medicine in Bangladesh: a cross-sectional study

BMC Research Notes, 2011
Background Herbal Medicines (HMs) are playing major roles in the health of the millions of people worldwide. Muslim Religious Leader (MRLs), being an important component of the society with huge influence on it, could contribute a lot to promote HM. This
Rashid Md Aminur, Yoshida Yoshitoku, Harun-Or-Rashid Md, Nahar Salmun, Sakamoto Junichi   +4 more
doaj   +1 more source

Elimination Profile of Deflazacort and Metabolites in Urine and Plasma Following Oral Administration: Relevance to Sports Drug Testing

Drug Testing and Analysis, EarlyView.
Results confirm that the MRL of 30 ng/mL for 21‐desacetyl‐deflazacort together with a 3‐day washout period is an appropriated strategy to detect oral deflazacort administration in sport competition. ABSTRACT Deflazacort (DEF) is a glucocorticoid prohibited in sports competitions when orally administered.
Sergi Coll, Claudia Bressan, Núria Monfort, Ana Aldea‐Perona, Marcel·lí Carbó, Rosa Ventura   +5 more
wiley   +1 more source

Genetically Engineered Nanobody–Recombinant Antibody Colloidal Gold Strip for Ultrasensitive Atrazine Detection in Fruits and Vegetables

Food Safety and Health, EarlyView.
A sensitive colloidal gold immunochromatographic assay for atrazine was successfully established using genetically engineered nanobody‐recombinant antibody, which overcame the shortcomings of traditional antigen‐antibody. ABSTRACT Colloidal gold immunochromatography (CG‐ICA) is distinguished by its cost‐effectiveness and rapid detection capabilities ...
Jiayong Bao, Peipei Li, A. M. Abd El‐Aty, Jing Zhao, Lingyuan Xu, Chenxi Guo, Jia Li, Xingmei Lei, Sensen Feng, Yi Liu, Si Chen, Fen Jin, Jing Wang, Lufei Zheng, Zhen Cao, Bruce D. Hammock, Maojun Jin   +16 more
wiley   +1 more source