Results 191 to 200 of about 2,706,783 (351)

2'-hydroxyl modification improves enzymatic and thermal stability of mRNA. [PDF]

Mol Ther Nucleic Acids
Uchida S.
europepmc   +1 more source

The Design, Construction, And Testing of mRNA Vaccine Against Equine Herpes Virus

Bhawana Devkota, Bhawana Devkota
openalex   +2 more sources

Evidence for U-tail Stabilization of gRNA/mRNA Interactions in Kinetoplastid RNA Editing [PDF]

, 2004
Donna J. Koslowsky, Larissa Reifur, Laura E. Yu, Weiqin Chen   +3 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Process and analytical strategies for the safe production of mRNA vaccines and therapeutics. [PDF]

Mol Biol Rep
Nowak CJA, Liu S, Falconer RJ, Gerstweiler L.   +3 more
europepmc   +1 more source

mRNA [PDF]

, 2018
openaire   +2 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Development of an mRNA Vaccine for Tick-Borne Encephalitis: Selection of a Prototype Virus Strain. [PDF]

Vaccines (Basel)
Nikiforova MA, Gushchin VA, Kleymenov DA, Kocherzhenko AM, Bykonia EN, Mazunina EP, Kozlova SR, Russu LI, Kuznetsova NA, Shidlovskaya EV, Marchuk EV, Usachev EV, Usacheva OV, Shcheblyakov DV, Kozlova IV, Tkachev SE, Pochtovyi AA, Zlobin VI, Logunov DY, Gintsburg AL.   +19 more
europepmc   +1 more source

EnteroMix and the emerging role of MRNA-based therapeutics in colorectal cancer: from preclinical tumor regression to clinical translation

Mohamad Khalil, Muhammad Hassan, Mahnoor Fatima, Muhammad Talha, Omar Abdullah Gill   +4 more
openalex   +1 more source

Postmenopausal increase in KiSS-1, GPR54, and luteinizing hormone releasing hormone (LHRH-1) mRNA in the basal hypothalamus of female rhesus monkeys

, 2008
WooRam Kim, Heather M. Jessen, Anthony P. Auger, Ei Terasawa   +3 more
openalex   +1 more source