Results 201 to 210 of about 1,519,200 (263)

Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses

Advanced Materials, EarlyView.
AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler, Hannah C. Safford, Ajay S. Thatte, Marshall S. Padilla, Elisa Battistini, Hannah M. Yamagata, Violet M. Ullman, Alex Chan, Benjamin E. Nachod, Anushka Agrawal, Maxwell B. Watkins, Jesse B. Hopkins, Andrew Tsourkas, Kushol Gupta, Michael J. Mitchell   +14 more
wiley   +1 more source

Thio-modification effects on mRNA translation using a PureCap-based capping method. [PDF]

RSC Chem Biol
Meng Z, Liu Y, Nakashima Y, Inagaki M, Kimura S, Kondo Y, Hashiya F, Abe N, Saito-Tarashima N, Minakawa N, Kimura Y, Abe H.   +11 more
europepmc   +1 more source

Rational design of a modular mRNA vaccine platform for rapid adaptation to SARS-CoV-2 variants. [PDF]

Sci Rep
Rudert J, Volckmar J, Jeron A, Bälkner M, Grimpe P, Jacobsen H, Zhang D, Bampi GB, Cicin-Sain L, Bruder D, Rosenecker J, Ding X.   +11 more
europepmc   +1 more source

Platelet-Targeted Self-Amplifying mRNA for Safe, Long-Acting Thromboprophylaxis. [PDF]

Circ Res
Song Y, Nguyen TH, Shi P, Refaat A, Pham CV, Xu B, Ren S, Skoraczynski JI, Nguyen A, Liu H, Klesen A, Trépout S, Vidallon MLP, Peter K, Wang X.   +14 more
europepmc   +1 more source

How Deeply Can mRNA Vaccines Affect the Responsiveness to Immune Checkpoint Inhibitors Through Changes in the Tumor Microenvironment? Evidence from Melanoma. [PDF]

Cells
Persico I, Doro MG, Frogheri L, Sini MC, Maestrale GB, Manca A, Mallardo D, Ascierto PA, Palmieri G.   +8 more
europepmc   +1 more source

Turning the clock: mRNA-encoded thymic factors restore aged immunity. [PDF]

Signal Transduct Target Ther
Khan MN, Li H, Li X.
europepmc   +1 more source

RNA-binding protein transcripts reflect composition of target mRNAs. [PDF]

Nucleic Acids Res
Kapral TH, Žagrović B.
europepmc   +1 more source