Results 241 to 250 of about 2,344,135 (339)

Idiopathic Pulmonary Fibrosis Caused by Damaged Mitochondria and Imbalanced Protein Homeostasis in Alveolar Epithelial Type II Cell

Advanced Biology, EarlyView.
By systematizing a large body of evidence and propose a cascade relationship between protein homeostasis, endoplasmic reticulum stress, mitochondrial dysfunction, and pro‐fibrotic factor, providing a theoretical basis for ATII cells dysfunction as a possible pathophysiological initiating event for idiopathic pulmonary fibrosis.
Zhaoxiong Dong, Xiaolong Wang, Peiwen Wang, Mingjian Bai, Tianyu Wang, Yanhui Chu, Yan Qin   +6 more
wiley   +1 more source

The transcriptional regulators GATA6 and TET1 regulate the TGF-β pathway in cancer-associated fibroblasts to promote breast cancer progression. [PDF]

Cell Death Discov
Ghazimoradi MH, Babashah S.
europepmc   +1 more source

Specificity of mRNA Binding Factor in Eukaryotes

, 1970
Stuart M. Heywood
openalex   +1 more source

Generation of Advanced Blood–Brain Barrier Spheroids Using Human‐Induced Pluripotent Stem Cell‐Derived Brain Capillary Endothelial‐Like Cells

Advanced Biology, EarlyView.
In this article, the establishment and characterization of a self‐assembled 3D BBB spheroid model using human induced pluripotent stem cell (hiPSC)‐derived and primary cells is reported. Spheroids demonstrate in‐vivo like tight junction ultrastructure and, in comparison to 2D mono‐cultures, higher transcript expression of BBB specific genes.
Sanjana Mathew‐Schmitt, Sabrina Oerter, Evelin Reitenbach, Sabine Gätzner, Alevtina Höchner, Heinz‐Georg Jahnke, Jörg Piontek, Winfried Neuhaus, Andreas Brachner, Marco Metzger, Antje Appelt‐Menzel   +10 more
wiley   +1 more source

A novel in-vitro expression assay by LC/MS/MS enables multi-antigen mRNA vaccine characterization. [PDF]

Sci Rep
Wang HL, Kajbaf K, Gau BC, Dawdy AW, Edwards R, Bare B, Raymundo G, Iturrizaga J, Ernsky C, Walker M, Byrne EB, Boslett J, Campbell A, Matthessen R, Goffin B, Cirelli D, Rouse JC, Van Pottelberge R, Friese OV.   +18 more
europepmc   +1 more source

Interaction of a limited set of proteins with different mRNAs and protection of 5′-caps against pyrophosphatase digestion in initiation complexes [PDF]

, 1979
Nahum Sonenberg, Maureen A. Morgan, Douglas Testa, Richard J. Colonno, Aaron J. Shatkin   +4 more
openalex   +1 more source

Depletion of TP53 in Human Pluripotent Stem Cells Triggers Malignant‐Like Behavior

Advanced Biology, EarlyView.
Human pluripotent stem cells (hPSCs) with TP53‐depleting mutations are generated, mimicking commonly occurring events in vitro. Loss of TP53 does not alter pluripotency status or in vitro differentiation potential but causes genetic instability and transcriptome changes and confers superior clonal and anchorage‐free growth and higher chemotherapeutic ...
Joaquin Montilla‐Rojo, Thomas F. Eleveld, Marnix van Soest, Sanne Hillenius, Dennis M. Timmerman, Ad J. M. Gillis, Bernard A. J. Roelen, Christine L. Mummery, Leendert H. J. Looijenga, Daniela C. F. Salvatori   +9 more
wiley   +1 more source

Applications of mRNA Delivery in Cancer Immunotherapy. [PDF]

Int J Nanomedicine
Pan X, Zhang YW, Dai C, Zhang J, Zhang M, Chen X.   +5 more
europepmc   +1 more source

Light regulation of specific mRNA species in Lemna gibba L. G-3

, 1978
Elaine M. Tobin
openalex   +1 more source

Transcription of the genome of adenovirus type 12. I. Viral mRNA in abortively infected and transformed cells [PDF]

, 1975
Juan Ortı́n, Walter Doerfler
openalex   +1 more source