Results 251 to 260 of about 3,391,200 (390)
Correlation between Protein and mRNA Abundance in Yeast
S. Gygi+3 more
semanticscholar +1 more source
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda+9 more
wiley +1 more source
Immunogenicity and safety of mRNA-based seasonal influenza vaccines encoding hemagglutinin and neuraminidase. [PDF]
Rudman Spergel AK+14 more
europepmc +1 more source
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra+17 more
wiley +1 more source
On the Dependency of Cellular Protein Levels on mRNA Abundance
Yansheng Liu, A. Beyer, R. Aebersold
semanticscholar +1 more source
Poly(4‐thiouridylic Acid) as Messenger RNA and Its Application for Photoaffinity Labelling of the Ribosomal mRNA Binding Site [PDF]
I. Fiser, K.H. Scheit, Ernst Kuechler
openalex +1 more source
Compound Heterozygous MRPS14 Variants Associated With Leigh Syndrome
ABSTRACT MRPS14 (uS14m) is a nuclear‐encoded ribosomal protein important for mitochondria‐specific translation. To date, only a single individual with a recessive MRPS14‐related disorder (also known as COXPD38) has been reported. We report an additional subject possessing novel compound heterozygous MRPS14 variants (p.Asp37Asn, p.Asn60Asp). The subject
Maria Gabriela Otero+15 more
wiley +1 more source
p62 mRNA suppresses NLRP1 expression in cutaneous SCC cells through miR-34a-5p. [PDF]
Hennig P+5 more
europepmc +1 more source