Results 41 to 50 of about 2,221,278 (207)

Peroxisome Proliferator-Activated Receptor alpha (PPAR alpha) down-regulation in cystic fibrosis lymphocytes [PDF]

, 2006
Background: PPARs exhibit anti-inflammatory capacities and are potential modulators of the inflammatory response. We hypothesized that their expression and/or function may be altered in cystic fibrosis (CF), a disorder characterized by an excessive host ...
A Augarten, A Linden, A Madej, A Trifilieff, AA Ionescu, AE Lovett-Racke, AP Sampson, B Staels, BM Forman, C Andersson, C Hubeau, C Hubeau, DC Jones, E Dagli, F Akbiyik, F McAllister, G Chinetti, H Pall, I Inoue, J Carlstedt-Duke, JD Dignam, JD Tugwood, JH Parmentier, JL Su, JM Shipley, JP Despres, JT Zakrzewski, K Balough, K Beier, KA Kreuzer, LS Nixon, M Ollero, M Roulet, MA Birrell, ME Poynter, N Marx, N Marx, P Delerive, P Greally, P Reineck, PM Farrell, PR Devchand, RB Moss, RB Moss, RB Moss, RU Sorensen, SD Freedman, SM Loitsch, SW Chung, TA Waldmann, TP Dean, TZ Khan, W Wahli, Z Israelian-Konaraki   +53 more
core   +4 more sources

Peptide-enhanced mRNA transfection in cultured mouse cardiac fibroblasts and direct reprogramming towards cardiomyocyte-like cells. [PDF]

, 2015
The treatment of myocardial infarction is a major challenge in medicine due to the inability of heart tissue to regenerate. Direct reprogramming of endogenous cardiac fibroblasts into functional cardiomyocytes via the delivery of transcription factor ...
Kim, Hyun Jin, Lee, Kunwoo, Lingampalli, Nithya, Murthy, Niren, Tang, Richard, Yu, Pengzhi   +5 more
core   +3 more sources

Effect of hypoxia, glutamine and glucose deprivation on the expression of mRNA of the retinoblastoma binding proteins in glioma cells

Біологічні студії, 2011
Hypoxia and ischemia, as well as endoplasmic reticulum stress, are principal factors which are necessary for tumor neovascularization and growth. We have studied the effect of blocking the endoplasmic reticulum – nuclei-1, the main signaling enzyme of ...
D. O. Minchenko, L. L. Karbovskyi, S. V. Danylovsky, M. Moenner, O. H. Minchenko   +4 more
doaj   +1 more source

DNA polymerase B deficiency is linked to aggressive breast cancer: a comprehensive analysis of gene copy number, mRNA and protein expression in multiple cohorts [PDF]

, 2014
Short arm of chromosome 8 is a hot spot for chromosomal breaks, losses and amplifications in breast cancer. Although such genetic changes may have phenotypic consequences, the identity of candidate gene(s) remains to be clearly defined.
Abayomi, M, Abdel-Fatah, TMA, Agarwal, D, Albarakati, N, Ball, G, Caldas, C, Chan, S, Ellis, IO, Madhusudan, S, Moseley, P, Perry, C, Russell, R   +11 more
core   +1 more source

Expression of ARHGEF11 mRNA in Schizophrenic Thalamus [PDF]

Annals of the New York Academy of Sciences, 2003
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/74092/1/annals.1300.030 ...
Davidkova, Genoveva, McCullumsmith, Robert E., Meador-Woodruff, James H.   +2 more
openaire   +3 more sources

The prognostic value of whole blood SOX2, NANOG and OCT4 mRNA expression in advanced small-cell lung cancer

Radiology and Oncology, 2016
The data on expression and clinical impact of cancer stem cell markers SOX2, NANOG and OCT4 in lung cancer is still lacking. The aim of our study was to compare SOX2, NANOG and OCT4 mRNA expression levels in whole blood between advanced small-cell lung ...
Sodja Eva, Rijavec Matija, Koren Ana, Sadikov Aleksander, Korošec Peter, Cufer Tanja   +5 more
doaj   +1 more source

Dietary chitosan affects metabolism of arachidonic acid in weaned piglets

Czech Journal of Animal Science, 2017
The effects of chitosan on immune function via arachidonic acid (AA) pathway in weaned piglets were investigated. A total of 180 piglets (Duroc × Yorkshire × Landrace) were randomly assigned to 5 dietary treatments and fed a basal diet supplemented with ...
Jun-Liang Li, Yuan-Qing Xu, Bin-Lin Shi, Deng-Sheng Sun, Su-Mei Yan, Xiao-Yu Guo   +5 more
doaj   +1 more source

Quantitative Expression of C-Type Lectin Receptors in Humans and Mice [PDF]

, 2012
C-type lectin receptors, their adaptor molecules and S-type lectins (galectins) are involved in the recognition of glycosylated self-antigens and pathogens.
Akira, Anders, Bjorge, Camby, Caminschi, Christoph Römmele, Elola, Ferwerda, Geijtenbeek, Gingras, Gringhuis, Gross, Hans-Joachim Anders, Heil, Heni Eka Susanti, Hornung, Kimbrell, Kock, Kono, Kronin, Kulkarni, Lassen, Lech, Lech, Lech, Lopez-Guisa, Maciej Lech, Medzhitov, Mocsai, Osorio, Patole, Rakoff-Nahoum, Regina Gröbmayr, Roman Günthner, Schreibelt, Skuginna, Van Vliet, Wagner, Zarember, Zhang   +39 more
core   +5 more sources

Antibiotics Feeding Accelerate Functional Maturation of Intestinal Immune-Related Cells of Male Broiler Chicks after Hatch

The Journal of Poultry Science, 2011
Developmental changes in immune-related cells of the upper and lower gut during the first 2 weeks post-hatch were determined in broiler chickens fed a corn-soybean meal based diet with or without antibiotics (salinomycin and enramycin). In the upper gut,
Kazuaki Takahashi, Yoshiko Miura, Takanori Mizuno   +2 more
doaj   +1 more source

Optimization of mRNA untranslated regions for improved expression of therapeutic mRNA [PDF]

RNA Biology, 2018
mRNA based therapies hold great promise for the treatment of genetic diseases. However, this therapeutic approach suffers from multiple challenges including the short half-life of exogenously administered mRNA and subsequent protein production.
Kirtika H. Asrani, Jeremiah D. Farelli, Mary R. Stahley, Rebecca L. Miller, Christopher J. Cheng, Romesh R. Subramanian, Jeffrey M. Brown   +6 more
openaire   +2 more sources