The Journal of Poultry Science, 2009 Glutathione peroxidase 1 (cellular glutathione peroxidase, EC 1.11.1.9 (GPX1)) is an antioxidant enzyme that plays an important role in scavenging reactive oxygen species to protect cells from oxidative damage.
Sopon Wilaison, Makoto Mori
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Biomolecular Concepts, 2020 The single nucleotide polymorphism (SNP) of the promoter region of MMP-1 (at 1607 bp) and MMP-3 (at 1171 bp) create Ets binding sites. Correlations between these SNPs and sensitivity to several biological processes such as metastasis and recurrence of ...
Prosper Bado +14 more
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Endocrine Regulations, 2019 Objective. The development of obesity and its metabolic complications is associated with dysregulation of various intrinsic mechanisms, which control basic metabolic processes through changes in the expression of numerous regulatory genes.
Minchenko Dmytro O.
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THE IMPACT OF GRAPHENE OXIDE NANOPARTICLES ON THE EXPRESSION OF ENDOPLASMIC RETICULUM STRESS-DEPENDENT GENES IS MORE PRONOUNCED IN NORMAL HUMAN ASTROCYTES THAN GLIOBLASTOMA CELLS [PDF]
Biotechnologia ActaAim. The purpose of the study was to investigate the impact of graphene oxide nanoparticles on the expression of a subset of ER stress-dependent genes in normal human astrocytes in comparison with glioblastoma cells depending on the knockdown of ERN1.
O.V. RUDNYTSKA +3 more
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EARLY CARDIAC DAMAGE FOLLOWING SINGLE AND COMBINED EXPOSURE TO LITHIUM CARBONATE AND LEAD ACETATE IN RATS: A TOXICOLOGICAL PERSPECTIVE [PDF]
Exploratory Animal and Medical ResearchEnvironmental contamination by heavy metals, especially lithium (Li) and lead (Pb), is of growing concern due to their increasing industrial applications and accumulation in ecosystems.
Harsh R. Patel
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Endocrine Regulations, 2020 Objective. The aim of the present study was to investigate the effect of adipokine NAMPT (nicotinamide phosphoribosyltransferase) silencing on the expression of genes encoding IRS1 (insulin receptor substrate 1) and some other proliferation related ...
Tsymbal Daria O. +5 more
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O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation [PDF]
, 2011 Background: We analyzed prospectively whether MGMT (O(6)-methylguanine-DNA methyltransferase) mRNA expression gains prognostic/predictive impact independent of MGMT promoter methylation in malignant glioma patients undergoing radiotherapy with ...
Kreth Simone +35 more
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Trichostatin A induces 5-lipoxygenase promoter activity and mRNA expression via inhibition of histone deacetylase 2 and 3 [PDF]
, 2012 The 5-lipoxygenase (5-LO) is the key enzyme in the formation of leukotrienes. We have previously shown that the histone deacetylase (HDAC) inhibitor trichostatin A (TSA) activates 5-LO transcription via recruitment of Sp1, Sp3 and RNA polymerase II to ...
Julia Metzner +13 more
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Quantification of pre-mRNA escape rate and synergy in splicing [PDF]
, 2014 Splicing reactions generally combine high speed with accuracy. However, some of the pre-mRNAs escape the nucleus with a retained intron. Intron retention can control gene expression and increase proteome diversity.
Becskei, Attila +13 more
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Kaposin-B enhances the PROX1 mRNA stability during lymphatic reprogramming of vascular endothelial cells by Kaposi's sarcoma herpes virus. [PDF]
, 2010 Kaposi's sarcoma (KS) is the most common cancer among HIV-positive patients. Histogenetic origin of KS has long been elusive due to a mixed expression of both blood and lymphatic endothelial markers in KS tumor cells.
Kafka, Darren +37 more
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