Results 11 to 20 of about 2,206,670 (309)

Hypoxic regulation of mRNA expression [PDF]

open access: yesCell Cycle, 2008
Many tumors are hypoxic, and cells that are experimentally rendered hypoxic display a variety of phenotypes which allow them to adapt to the micro-environment. These phenotypes include a shift from aerobic to anaerobic metabolism, a diminution of reactive oxygen species, an arrest of proliferation, apoptosis, and a secretion of pro-angiogenic growth ...
Lawrence B, Gardner, Paul G, Corn
openaire   +2 more sources

HuR mRNA Ligands Expressed After Seizure [PDF]

open access: yesJournal of Neuropathology and Experimental Neurology, 2005
HuR is a ubiquitously expressed AU-rich element (ARE)-binding protein that interacts with and stabilizes selective early response gene (ERG) mRNAs after cell activation or stress. To date, approximately 20 mRNAs have been unambiguously defined as HuR ligands.
Cara J, Westmark   +6 more
openaire   +2 more sources

Reference genes for measuring mRNA expression [PDF]

open access: yesTheory in Biosciences, 2012
The aim of this review is to find answers to some of the questions surrounding reference genes and their reliability for quantitative experiments. Reference genes are assumed to be at a constant expression level, over a range of conditions such as temperature.
Dundas, J, Ling, M
openaire   +3 more sources

Diurnal difference in CAR mRNA expression [PDF]

open access: yesNuclear Receptor, 2004
Abstract Background The constitutive androstane receptor (CAR, NR1I3) plays a key role in the transcriptional activation of genes that encode xenobiotic/steroid and drug metabolizing enzymes. Results The expression of CAR mRNA ...
Kanno, Yuichiro   +4 more
openaire   +2 more sources

Cytokine mRNA Expression in Painful Radiculopathy [PDF]

open access: yesThe Journal of Pain, 2009
Inflammatory cytokines contribute to lumbar radiculopathy. Regulation of cytokines for transient cervical injuries, with or without longer-lasting inflammation, remains to be defined. The C7 root in the rat underwent compression (10gf), chromic gut suture exposure (chr), or their combination (10gf+chr).
Sarah M, Rothman   +4 more
openaire   +2 more sources

Down-regulation of zinc levels in children patients with pityriasis simplex: association with the oxidative stress pathway?

open access: yesPifu-xingbing zhenliaoxue zazhi, 2022
Objective To assess serum levels of zinc in children patients with pityriasis alba (PA) and study mRNA expression profile of oxidative stress pathway by bioinformatics technology to investigate the relationship between oxidative stress and PA.
Xianhua TANG   +5 more
doaj   +1 more source

Split-BioID a conditional proteomics approach to monitor the composition of spatiotemporally defined protein complexes

open access: yesNature Communications, 2017
The BioID approaches takes advantage of the promiscuous biotinylation enzyme (BirA*) to identify proteins that closely interact. Here the authors improve the resolution of BioID using a protein fragment complementation approach that allows the assignment
Isabel Myriam Schopp   +6 more
doaj   +1 more source

Ciprofloxacin enhances the stimulation of matrix metalloproteinase 3 expression by interleukin-1beta in human tendon-derived cells [PDF]

open access: yes, 2002
To determine whether the fluoroquinolone antibiotic ciprofloxacin, which can cause tendon pain and rupture in a proportion of treated patients, affects the expression of matrix metalloproteinases (MMPs) in human tendon-derived cells in culture.
Astrom   +16 more
core   +1 more source

Chinese herbal Jin-Ying-Tang attenuates the inflammatory response by inhibiting the activation of TLR4/MyD88/TRAF-6/NIK pathway at the mRNA level in LPS-stimulated mouse mammary epithelial cells

open access: yesJournal of Veterinary Research, 2016
Introduction: The effects of Jin-Ying-Tang (JYT) on Toll-like Receptor 4 (TLR4) signalling transduction of lipopolysaccharide (LPS)-stimulated mouse mammary epithelial cells (MECs) in vitro were examined.
Yi Qiong   +6 more
doaj   +1 more source

cDNA Cloning and mRNA Expression of Androgen Receptor in Male Japanese Quail (Coturnix coturnix japonica)

open access: yesThe Journal of Poultry Science, 2006
The biological activities of androgen are largely mediated via androgen receptor (AR). Although a partial sequence AR cDNA was revealed in canaries and zebra finch, AR cDNA has not been cloned in quail and chickens.
Shusei Mizushima   +2 more
doaj   +1 more source

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