Results 11 to 20 of about 4,884,325 (258)
MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction [PDF]
Background: MicroRNA (miRNA) directed gene repression is an important mechanism of posttranscriptional regulation. Comprehensive analyses of how microRNA influence biological processes requires paired miRNA-mRNA expression datasets.
Wilson, Paul +5 more
core +8 more sources
The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression [PDF]
Background Telomerase is a ribonucleoprotein enzyme that synthesises telomeres after cell division and maintains chromosomal stability leading to cellular immortalisation.
Newbold, RF, Kirkpatrick, KL, Mokbel, K
core +1 more source
Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay [PDF]
5-Lipoxygenase (5-LO) catalyzes the two initial steps in the biosynthesis of leukotrienes (LT), a group of inflammatory lipid mediators derived from arachidonic acid.
Laura Pufahl (182448) +26 more
core +2 more sources
Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system [PDF]
This work was supported by Medical Research Scotland (FRG353 to VAS), the FP7- Directorate-General for Research and Innovation of the European Commission (EU HEALTHF4-2012-305033 to Coordinating Action Systems Medicine to DJH); the Chief Scientist Office
Smith, V. Anne +7 more
core +1 more source
Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast [PDF]
Splicing of pre-mRNA is a critical step in mRNA maturation and disturbances cause several genetic disorders. We apply the synthetic tetracycline (tc)-binding riboswitch to establish a gene expression system for conditional tc-dependent control of pre ...
Weigand, Julia E. +3 more
core +1 more source
The Role of Regulated mRNA Stability in Establishing Bicoid Morphogen Gradient in Drosophila Embryonic Development [PDF]
The Bicoid morphogen is amongst the earliest triggers of differential spatial pattern of gene expression and subsequent cell fate determination in the embryonic development of Drosophila.
Niranjan Mahesan +5 more
core +3 more sources
Objective. The aim of the present investigation was to examine the effect of inhibition of endoplasmic reticulum stress signaling, mediated by IRE1 (inositol requiring enzyme 1), which is a central mediator of the unfolded protein response on the ...
Minchenko D.O. +4 more
doaj +1 more source
In laying hens, dietary betaine supplementation is reported to reduce abdominal fat, however, the mechanism of which remains largely unknown. The present study investigated the effect of dietary betaine supplementation on mRNA expression and the ...
Jinyi Xing +5 more
doaj +1 more source
Despite recent taxonomic diversification in studies linking genotype with phenotype, follow-up studies aimed at understanding the molecular processes of such genotype-phenotype associations remain rare.
Johanna Kurko +5 more
doaj +1 more source
Objective. The aim of the present study was to examine the effect of inhibition of endoplasmic reticulum stress signaling, mediated by IRE1 (inositol requiring enzyme 1), which is a central mediator of the unfolded protein response on the expression of ...
Do Minchenko +3 more
doaj +1 more source

