Results 11 to 20 of about 4,884,325 (258)

MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction [PDF]

open access: yes, 2012
Background: MicroRNA (miRNA) directed gene repression is an important mechanism of posttranscriptional regulation. Comprehensive analyses of how microRNA influence biological processes requires paired miRNA-mRNA expression datasets.
Wilson, Paul   +5 more
core   +8 more sources

The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression [PDF]

open access: yes, 2004
Background Telomerase is a ribonucleoprotein enzyme that synthesises telomeres after cell division and maintains chromosomal stability leading to cellular immortalisation.
Newbold, RF, Kirkpatrick, KL, Mokbel, K
core   +1 more source

Post-transcriptional regulation of 5-lipoxygenase mRNA expression via alternative splicing and nonsense-mediated mRNA decay [PDF]

open access: yes, 2012
5-Lipoxygenase (5-LO) catalyzes the two initial steps in the biosynthesis of leukotrienes (LT), a group of inflammatory lipid mediators derived from arachidonic acid.
Laura Pufahl (182448)   +26 more
core   +2 more sources

Relationship between differentially expressed mRNA and mRNA-protein correlations in a xenograft model system [PDF]

open access: yes, 2015
This work was supported by Medical Research Scotland (FRG353 to VAS), the FP7- Directorate-General for Research and Innovation of the European Commission (EU HEALTHF4-2012-305033 to Coordinating Action Systems Medicine to DJH); the Chief Scientist Office
Smith, V. Anne   +7 more
core   +1 more source

Tetracycline aptamer-controlled regulation of pre-mRNA splicing in yeast [PDF]

open access: yes, 2007
Splicing of pre-mRNA is a critical step in mRNA maturation and disturbances cause several genetic disorders. We apply the synthetic tetracycline (tc)-binding riboswitch to establish a gene expression system for conditional tc-dependent control of pre ...
Weigand, Julia E.   +3 more
core   +1 more source

The Role of Regulated mRNA Stability in Establishing Bicoid Morphogen Gradient in Drosophila Embryonic Development [PDF]

open access: yes, 2011
The Bicoid morphogen is amongst the earliest triggers of differential spatial pattern of gene expression and subsequent cell fate determination in the embryonic development of Drosophila.
Niranjan Mahesan   +5 more
core   +3 more sources

Inhibition of IRE1 signaling affects the expression of genes encoded glucocorticoid receptor and some related factors and their hypoxic regulation in U87 glioma cells

open access: yesEndocrine Regulations, 2016
Objective. The aim of the present investigation was to examine the effect of inhibition of endoplasmic reticulum stress signaling, mediated by IRE1 (inositol requiring enzyme 1), which is a central mediator of the unfolded protein response on the ...
Minchenko D.O.   +4 more
doaj   +1 more source

Effect of Dietary Betaine Supplementation on mRNA Expression and Promoter CpG Methylation of Lipoprotein Lipase Gene in Laying Hens

open access: yesThe Journal of Poultry Science, 2009
In laying hens, dietary betaine supplementation is reported to reduce abdominal fat, however, the mechanism of which remains largely unknown. The present study investigated the effect of dietary betaine supplementation on mRNA expression and the ...
Jinyi Xing   +5 more
doaj   +1 more source

Transcription Profiles of Age-at-Maturity-Associated Genes Suggest Cell Fate Commitment Regulation as a Key Factor in the Atlantic Salmon Maturation Process

open access: yesG3: Genes, Genomes, Genetics, 2020
Despite recent taxonomic diversification in studies linking genotype with phenotype, follow-up studies aimed at understanding the molecular processes of such genotype-phenotype associations remain rare.
Johanna Kurko   +5 more
doaj   +1 more source

Hypoxic regulation of the expression of genes encoded estrogen related proteins in U87 glioma cells: eff ect of IRE1 inhibition

open access: yesEndocrine Regulations, 2017
Objective. The aim of the present study was to examine the effect of inhibition of endoplasmic reticulum stress signaling, mediated by IRE1 (inositol requiring enzyme 1), which is a central mediator of the unfolded protein response on the expression of ...
Do Minchenko   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy