ESBL-producing bacteria and MRSA isolated from poultry and turkey products imported from Italy
ESBL and MRSA-producing bacteria in food-producing animals may contribute to increased incidences of infection in humans. This study was carried out on 38 samples obtained from 32 chickens and 6 turkey products purchased at retail outlets of Hannover ...
Chiara BENINATI +6 more
doaj +1 more source
cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression
cGAS is a cytosolic DNA sensor known for innate immune defense. cGAS binds and suppresses ALDH2 are showed, limiting acetyl‐CoA production. cGAS loss activates ALDH2, promoting histone acetylation, lipogenesis, and lipid droplets accumulation. cGas‐/‐ mice on a high‐fat diet show signs of worsened MASLD.
Ying Wang +14 more
wiley +1 more source
Laboratory data as a quality indicator of health-care-associated infections in England. [PDF]
Routine diagnostic laboratory results, e.g. numbers of meticillin-resistant Staphylococcus aureus (MRSA) bacteraemias, have been used as health-care-associated infection quality indicators for decades. The English health-care-associated infection quality
Jeyaratnam, D, Planche, T
core +1 more source
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan +6 more
wiley +1 more source
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen +22 more
wiley +1 more source
Incorporation of Homologous and Heterologous Proteins in the Saccharomyces cerevisiae Cell Wall
The yeast cell wall is a structure of pronounced complexity and principally consists of two structurally and functionally different moieties. The inner layer is predominantly built of glucan and it provides mechanical stability to the cell.
Renata Teparić +2 more
doaj
Ceftaroline fosamil – fifth-generation cephalosporin with anti-MRSA activity in the treatment of severe infections in pediatric practice [PDF]
Сeftaroline fosamil is a fifth-generation cephalosporin and a unique β-lactam and the only currently registered in the Russian Federation cephalosporin with activity against MRSA. Сeftaroline is approved for use in pediatric practice for the treatment of
Andreeva I.V. +2 more
doaj +1 more source
Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin +3 more
wiley +1 more source
Detection of clfA, clfB and coa genes in Methicillin-Resistant Staphylococcus aureus (MRSA) isolated from Nasal Cavity of Cows, Buffalo and their Breeders in Nineveh Governorate, Iaq [PDF]
The present study aimed to isolate and identify Methicillin-Resistant Staphylococcus aureus MRSA from the nasal cavity of healthy cows and buffaloes and their breeders in Nineveh Governorate and detect some virulence factors by using molecular methods. A
H. Rahma, Dh. Jwher
doaj +1 more source
Survey of policy for MRSA screening in English cataract surgical units and changes to practice after updated National guidelines [PDF]
National guidelines on MRSA (methicillin-resistant Staphylococcus aureus) screening policy in England have changed on a number of occasions, but there is limited data on its influence at a local level. The aim of this study was to determine if changes in
Herbert, L, Joshi, L, West, SK
core

