Results 231 to 240 of about 42,200 (256)

Invasive Acantholytic Extramammary Paget's Disease of the Vulva With Mammary Carcinoma-Like Differentiation and MMR Loss: Report of an Unusual Case and Its Clinical Mimics. [PDF]

Gynecol Oncol Rep
Claus J, Pearce J, Bojko A, Manrai P, Quddus MR, Marketkar S.   +5 more
europepmc   +1 more source

Lynch syndrome caused by SINE-VNTR-Alu-F retrotransposon insert in MSH6 confirmed after 20 years of testing: a case report and literature review. [PDF]

Hered Cancer Clin Pract
Sjursen W, Svaasand EK, Gilde B, Ravi A, Korseth KM, Singh AK, Johansen J, Rødningen OK, Sevatdal SG, Hegre SA, Olsen MF, Misund K.   +11 more
europepmc   +1 more source

Population frequency of Predicted pathogenic MisMatch Repair (MMR) gene variants in Lynch syndrome from bioinformatic analyses of the general population. [PDF]

Sci Rep
Guan Y, Huang M, Macrae F, Yin X, Plazzer JP, Savige J.   +5 more
europepmc   +1 more source

Impact of Arsenite on Transient and Persistent Histone H3 Modifications and Transcriptional Response. [PDF]

Chem Res Toxicol
Lumpp T, Hijazi H, Stößer S, Tekin E, Brunner L, Fischer F, Brugière S, Pflieger D, Hartwig A.   +8 more
europepmc   +1 more source

Occurrence of dMMR/MSI-H tumor during follow-up in Lynch syndrome patients treated with immune checkpoint inhibitors for metastatic digestive cancer between 2015 and 2024: a retrospective analysis of a monocentric prospective cohort study. [PDF]

ESMO Open
Pellat A, Loisel C, Metras J, Lefevre JH, Parc Y, Cohen R, Samaille T, Perrier A, Dardenne A, André T.   +9 more
europepmc   +1 more source

Microsatellite Instability and Myometrial Infiltration in Low-Grade Endometrial Cancer: A Focus on MMR Heterodimer Dysfunction by a Retrospective Multicentric Italian Study. [PDF]

J Pers Med
Ronsini C, Restaino S, Di Donna MC, Cucinella G, Solazzo MC, De Franciscis P, Vizzielli G, Ludovisi M, Chiantera V.   +8 more
europepmc   +1 more source

MSH2, apoptosis, and carcinogenesis

, 1998
openaire   +1 more source

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Msh2 Deficiency Attenuates But Does Not Abolish Thiopurine Hematopoietic Toxicity in Msh2-- Mice

Molecular Pharmacology, 2003
The amount of MSH2 protein, a major component of the mismatch repair system, was found to differ >10-fold in leukemia cells from children with newly diagnosed acute lymphoblastic leukemia, with a subgroup of patients (17%) having undetectable MSH2 protein.
Natalia F, Krynetskaia, Timothy L, Brenner, Eugene Y, Krynetski, Weinan, Du, John C, Panetta, Pui, Ching-Hon, William E, Evans   +6 more
openaire   +5 more sources

MLH1 and MSH2 Expression in Pterygia

Cornea, 2007
Pterygia have been reported to share some of the genetic defects seen in cancers, including microsatellite instability (MSI). We examined pterygia for the presence of proteins typically missing or defective in adenocarcinomas with MSI. We also performed microsatellite analysis on DNA from pterygia to test for instability in the size of the ...
Barbara G, Schneider, Deshdeepak, Sahni, Juan C, Torres, Nicholas, Dushku, Ted W, Reid   +4 more
openaire   +2 more sources