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MSOT-Guided Nanotheranostics for Synergistic Mild Photothermal Therapy and Chemotherapy to Boost Necroptosis/Apoptosis

ACS Applied Materials & Interfaces, 2022
The development of nanotheranostics for precision imaging-guided regulated cell death-mediated synergistic tumor therapy is still challenging. Herein, a novel multifunctional nanotheranostic agent, iRGD-coated maleimide-poly(ethylene glycol)-poly(lactic acid/glycolic acid)-encapsulated hydrophobic gold nanocages (AuNCs) and hydrophilic epigallocatechin
Shiying Li, Wai-Sum Lo, Yan-Juan Gu
exaly   +4 more sources

Sensitivity of molecular target detection by multispectral optoacoustic tomography (MSOT)

Medical Physics, 2009
Optoacoustic imaging is emerging as a noninvasive imaging modality that can resolve optical contrast through several millimeters to centimeters of tissue with the resolution achieved by ultrasound imaging. More recently, applied at multiple illumination wavelengths, multispectral optoacoustic tomography (MSOT) offered the ability to effectively ...
Daniel, Razansky   +2 more
openaire   +2 more sources

Brittle Fracture Assessments on Piping Systems: MSOT Curves

Volume 3: Design and Analysis, 2019
Abstract Brittle fracture assessments (BFAs) of pressure vessels based on API 579-1/ASME FFS-1, Section 3 procedures are frequently easier and more straightforward to implement in comparison to the BFAs on piping systems. Specifically, the development of the MSOT curves.
Ishita Chakraborty   +2 more
openaire   +1 more source

Mesoscopic Imaging using Multi Spectral Optoacoustic Tomography (MSOT)

Conference on Lasers and Electro-Optics/International Quantum Electronics Conference, 2009
The talk describes next generation high-resolution photonic tissue imaging that goes beyond the penetration limit of optical ...
Vasilis Ntziachristos, Daniel Razansky
openaire   +1 more source

Multispectral Optoacoustic Tomography (MSOT) Characterization in Resolving Molecular Biomarkers

2009
Fluorochromes are essential biological reporters in many areas of biomedical research and, in particular, molecular imaging applications. We demonstrate the basic performance characteristics of multispectral optoacoustic tomography in resolving fluorochromes in tissue-mimicking phantoms.
Taruttis, A.   +4 more
openaire   +2 more sources

Quantitative imaging of tumor vasculature using multispectral optoacoustic tomography (MSOT)

SPIE Proceedings, 2017
The ability to evaluate tumor oxygenation in the clinic could indicate prognosis and enable treatment monitoring, since oxygen deficient cancer cells are often more resistant to chemotherapy and radiotherapy. MultiSpectral Optoacoustic Tomography (MSOT) is a hybrid technique combining the high contrast of optical imaging with spatial resolution and ...
Tomaszewski, Michal R.   +3 more
openaire   +2 more sources

Advancing biological imaging with multi-spectral optoacoustic tomography (MSOT)

2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2009
Multi-spectral optoacoustic tomography (MSOT) is an imaging method that can resolve fluorochromes and other reporter molecules with high sensitivity and specificity deep inside live animals and tissues. The method can penetrate for several millimeters to centimeters in tissues and offers resolutions in the 30 – 100 micron range.
openaire   +1 more source

Abstract 4269: Dynamic contrast-enhanced MSOT imaging to intratumoral pharmacokinetic modeling

Cancer Research, 2018
Abstract Introduction: Interactions between biological features and nanoparticles could affect tracer biodistribution, kinetics, clearance, and translocation. Because these effects cannot be simply extrapolated from in vitro studies, in vivo quantitative data are needed to determine the pharmacokinetic properties of tracers.
Ted G. Xiao   +7 more
openaire   +1 more source

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